“likely to be significant”

Given that women suffered worse economic and occupational losses during COVID-19, in combination with coming from a lower material baseline compared to men, there are likely to be significant effects in the medium and long term for women who remain under and unemployed.

Even with grasping suture techniques there is likely to be significant suture sliding along longitudinal fascicles.

Nevertheless, it is widely believed that programmed changes in promoter utilization, exon inclusion/exclusion, and 3′ end formation are likely to be significant driver processes in transformation.

We expect that the costs of caring for people at the end of life are likely to be significant in all countries, yet differences in the structure of health and social care systems require analysis to be conducted on a country by country basis.

While this is likely to be a significant financial undertaking, the direct and indirect cost savings are likely to be significant [ 39 ].

Gratitude has been found to have a strong positive influence on prosocial behavior among individuals with low socioeconomic status, suggesting that both gratitude and general life satisfaction are likely to be significant factors affecting patriotism ( Yost-Dubrow and Dunham, 2018 ).

The latter constraint may be relatively unimportant for mosquitoes and other flying arthropods but is likely to be significant for less mobile taxa such as ticks.

Although norovirus GI/GII was sixth as the most frequently detected enteropathogen in our study, its contribution to diarrhea etiology is likely to be significant given the suspected carriage of some of the top detected enteropathogens.

Gambling is likely to be significant contributing factor for some people, and should be considered when assessing the treatment and support needs of the homeless.

When we compared average read count to fold change in poly(A) tail lengths between 4SA and 4SD cells, the number of genes with significantly longer tails increased with read count ( Supplementary Figure S6C ), highlighting the possibility that the observed difference in poly(A) tail length is indeed transcriptome-wide, but highly expressed genes are more likely to be significant in our sequencing-based method.

While this effect may not be clinically significant for fluoxetine because of its long half-life, it is likely to be significant for paroxetine [ 28 ].

13 , 14 Because screening is an emotional experience for parents and potentially stressful for children, it is important to avoid an approach that will result in many false positives and negatives, as the consequences and emotional impact of being told a child has autism are likely to be significant. 15 , 16 It is also possible that children with slow development as toddlers may improve to similar levels as their peers when older, and some evidence suggests that even children who meet ASD criteria at very young ages may improve to sub-clinical levels later on. 17 , 18 Thus, screening might be inappropriate if carried out too early as it might result in false positive results due to an overtly unstable diagnosis.

This is particularly important as the burden of dual sensory impairment (hearing and sight loss) in symptomatic cCMV is unclear but likely to be significant.

However, given that 5–15% of the adult population is affected, the direct and indirect economic consequences of the disease are likely to be significant.

In the present study, because USDs were located at city centers and the surrounding traffic was considerable, the effects of exhaust fumes were likely to be significant.

This logistical strategy allows targeted questioning about late effects that are most likely to be significant to a given patient.

331 Although few studies have looked specifically at family carer burden or intervention in HCC, it is recognised that needs of family members are likely to be significant.

The values were then hierarchically tested from most to least likely to be significant, with the paired, non-parametric Wilcoxon signed-rank test (JMP software, Version 5, SAS Institute, Cary, NC, USA) until the P -value was >0.05.

Firstly, there is likely to be significant under‐reporting of risk factors for arrhythmia such as family history of ventricular arrhythmia in the CPRD.

Transfer of genetic testing to diagnostic laboratories may make genetic testing more widely available but the costs of analysis are likely to be significant and may prevent accessibility to confirmatory genetic testing in many situations.

This is likely to be significant for the activation of the lipase as mutations in SLP-76 which block its ability to bind PLCγ1 lead to reduced TCR-induced PLCγ1 phosphorylation ( 42 ).

Furthermore, if a target is identified, there is likely to be significant variation in PK in patients infected with COVID-19 that is not properly accounted for in the simulation studies published.

Significance is first considered, in a high-level manner, at the screening stage, e.g., the decision to state that further EIA work is needed requires a judgement that there are likely to be significant effects.

In CoBRA patients, complete reconstructive surgery of the urinary tract may be necessary since there are likely to be significant defects in the urinary tract.

Thus, does TXA 2 signaling condition the metastatic niche to create a more nurturing environment? The effects of TP on cancer-associated fibroblasts have not been investigated; however, they are likely to be significant given the emerging role of these cells and TXA 2 signaling in tumor progression.