“likely to be significant”

There is evidence that COVID19 is already impacting most of these economies either directly or indirectly, and its combined effect on the Pacific population is likely to be significant.

This means that placebo-effects, likely to be significant in an intervention like rTMS, cannot be ruled out, and are indeed a likely contributor for the observed effects.

With already falling rates of Mass attendance, the longer-term impact of COVID-19 church closures is likely to be significant in determining the future size and distribution of the Catholic Church in Australia.

This again limits the potential generalisability of study findings given such a small sub-sample responded, and that there is likely to be significant bias within this population of responders.

That is, even a change of fractions of a percent in EMR is likely to be significant and meaningful.

To compare nested models (for measurement invariance testing), we used a Satorra-Bentler corrected chi-square difference test, as well as relative differences in additional fit indices, as chi-square difference testing is known to be affected by larger sample size so that it is more likely to be significant in larger samples ( 29 ).

Overall, the current findings suggest that there is likely to be significant clinical value in using DTI to predict cognitive functioning, particularly in the medium to long term post-TBI (>4 weeks), by which time there is a consistent relationship between cognitive functioning and FA and ADC/MD values in numerous large white matter tracts, as well as the whole brain.

Disease-specific factors are likely to be significant, as individuals with MHI may have unique needs for specific job resources, which could be addressed through employee assistance programs or accommodations (Follmer and Jones 2018 ).

8 If hyperthermia is identified in a neonate, it is likely to be significant, and therefore the clinician should attempt to identify the underlying cause and provide the appropriate treatment.

These factors create a unique context where the ripple effects of technological change on younger generations are likely to be significant and warrant closer examination.

Furthermore, inter-observer differences in detection accuracy are likely to be significant ( 31 ).

Whether we start at a CD4 count of 732 or 493/μL, the patient will be on therapy for over 40 to 50 years! There does not seem to be much benefit in waiting, and there is likely to be significant long-term harm.

As there is likely to be significant variation in densities of target populations across study locations and over time due to variation in environmental factors such as rainfall as well as sampling biases imposed by collection methods [ 15 , 109 , 153 – 155 ], field implementation of a statistically powered assessment of entomological endpoints could also require considerable resources.

Thus, the broader benefits of averted school-age children illnesses due to malaria complications is likely to be significant, underscoring that savings from averted complications have the potential to increase household disposable income leading to increased consumption, with potential to enhance welfare for both school-age children and the household.

Over the lifetime of the animals, the cumulative effects of p120-associated inflammation are likely to be significant, and not unlike the tumorigenic effects of ulcerative colitis, where the risk of cancer is increased by ∼18% over 30 years [29] .

Thus, DNAm sites that were found significant at age 9 were likely to be significant at age 15.

This suggested that there were likely to be significant differences among the key genes in the glutamate and GlcNAc synthesis pathways of these C. glutamicum strains.

Most studies on stunting in Ethiopia have focused on children aged 6–59 months, suggesting that the nutritional status of new-borns has been overlooked, but the impact is likely to be significant.

Although the exact cause of AOSD is unknown, aberrant activation of innate immune cells, such as neutrophils, monocytes, and macrophages, as well as excessive cytokine production, including IL-1β, IL-6, TNF-alpha (tumor necrosis factor-alpha) and IL-18 are likely to be significant contributing factors [ 4 ].

The exact costs of treatment of these children are not known, but are also likely to be significant since treatment of adult patients with IBS costs more than $20 billion per year [ 8 , 9 ].

Finally, we recognize that we may not be capturing the full diversity of SARS-CoV-2 circulating in the community, as our sampling of hospitalised patients represents a considerable bias towards people with severe disease, and there is likely to be significant under ascertainment of cases [ 34 ].

In addition to the direct effects of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, the downstream effects on cardiac patients who avoid infection are likely to be significant but will be difficult to quantify.

Other possible contributing factors could include effects associated with non-ideal shape of crater and concentration gradients present in the coatings, but these are less likely to be significant at such length scales.

As such, surveying physical function in addition to respiratory function and comparing it between individuals with PRISm and those with normal respiratory function is likely to be significant both clinically and in terms of social welfare generally.

Thus, does TXA 2 signaling condition the metastatic niche to create a more nurturing environment? The effects of TP on cancer-associated fibroblasts have not been investigated; however, they are likely to be significant given the emerging role of these cells and TXA 2 signaling in tumor progression.