“likely to be significant”

The correlation analysis indicated a marked negative association between the expression of miR-128 and RPN2, which suggested that miR-128 was likely to be significant in the control of RPN2 regulation ( Fig. 1C ).

A challenge that, while not observed in this sample, is likely to be significant in a clinical setting.

This is highlighted by current debates surrounding the ecological footprint of cryptocurrency and large language models 36 , 37 , both of which are likely to be significant influences on information flow but depend on massive increases in energy production.

However, there is likely to be significant underreporting [ 10 , 14 ] of cases for various reasons: data on confirmed cases only included those were admitted to the Ebola management centre, but not those who could not be admitted when bed capacity was reached.

Therefore, the potential energy barrier for inducing the structural changes is likely to be significant.

According to Marks,[ 15 ] the organism is likely to be significant as an etiologic agent when isolated from the skin and subcutaneous tissue, and seldom so from other sources.

42 ) discussed the placebo effect and reported that it was less likely to be significant because the improvements were sustained throughout the study periods.

Sustained CH 4 release to the atmosphere from thawing Arctic permafrost and dissociating hydrates were suggested to be positive and likely to be significant feedbacks to climate warming [ 4 , 5 ].

The increased activity observed for all of these variants is likely to be significant as increased or decreased RAC1 activation has also been detected in neurodevelopmental disorders caused by variants in TRIO 32 and HACE1 , 33 supporting the notion that tight regulation of the level of RAC1 activity is important for proper neurodevelopment and function.

1 , 2 In addition to active cases, there are likely to be significant numbers of asymptomatic carriers. 3 The most severe form of malaria results from infection with P. falciparum .

Lack of computer literacy and online access are likely to be significant factors affecting patient engagement with ePROs in the real world, and lower education level and non-working status are also possible barriers [ 15 ].

Since they regulate the crosstalk modules across the stages of COAD, these 62 ncRNAs are likely to be significant biomarkers for diagnosis, recurrence, metastasis, and prognosis, as well as treatment response.

Our analysis examines the economically optimal investment strategy in SICP to address future major disease outbreaks and assess whether there are likely to be significant benefits to such investments in the case of Ebola-like outbreaks.

The wizard knew the research questions of the experiment, but there were no hypotheses about group comparisons that were likely to be significant.

The effect on transmission, and thus the risk of harming others, is still a subject of research in the case of COVID, but also seems likely to be significant [ 59 ].

Interactions between carriers are likely to be significant enough to affect their conduction mechanism, as evidenced by the T −1/2 dependence of the logarithm of the conductivity in the variable-range hopping regime 8 , and makes the conduccting polymers excellent candidates to be electron glasses.

Serious events were likely to be significant for the athletes and, therefore, appropriate to explore the psychological processes associated with sport injury and illness.

Limited introgressed loci associated with local adaptation in the hybrid zone When hybrid fitness involves multiple loci with different impacts, those under strong selection are likely to be significant β outliers, whereas weakly selected loci will show excess ancestry based on α outliers ( Gompert and Buerkle, 2012 ; Guo et al., 2023a ).

However, CFI and RMSEA were considered as more rigorous indicators because χ 2 is likely to be significant with large sample sizes.

In particular, histone modifications play a strong role in transcriptional regulation, and are likely to be significant contributors to determining in vivo occupancy.

Segregation effects are also likely to be significant.

Unsubstantiated concerns have also been raised regarding the fate and potential side-effects of the foreign, genetically engineered DNA and, for animals that will enter the human food chain, the costs of proving safety are likely to be significant.

~2.5-fold Figure 4 ref [ 23 ]), the effect is likely to be significant given that quiescent CD4 + T lymphocytes are difficult to transfect with siRNAs and are metabolically inactive and carry out low levels of protein synthesis.

Pre-specifying the smallest effect size of interest ( 47 ) and/or employing the use of discovery samples for model-fitting and replication or holdout samples for model testing might also be useful ( 48 ), especially because small effects are likely to be significant when sample sizes are large.

Thus, does TXA 2 signaling condition the metastatic niche to create a more nurturing environment? The effects of TP on cancer-associated fibroblasts have not been investigated; however, they are likely to be significant given the emerging role of these cells and TXA 2 signaling in tumor progression.