GRP78 attracted our attention due to its high protein amount found in sparsely growing cells, and its highly significant difference in the two growth patterns (SW480: 3.3-fold, p = 0.0005, Figure 1B a, b, c ; HCT116: 2-fold, p = 0.0005, Figure 1B d, e, f ; single analyzed 2-DE areas are shown in Figure S1B ).
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The culprit plaque was acute thrombus, either rupture or erosion, in 45% of patients >40 years versus 68% of ≤40 years; the difference in the rate of erosions (14 versus 36%, respectively) was highly significant ( P = .0005).
There was a strong, positive, and highly significant relationship between MT and RT in all three groups of cats ( p < 0.0005).
From 1990 to 2000, however, there was a highly significant ( P < 0.0005; table S2) switch to 67% of glaciers advancing (median rate, 20.0 m year −1 ).
Reward probability, reward magnitude and their interaction each had a highly significant influence on subject choices (one-sample T-test on regression coefficients, all T(17)>4.6, all p <0.0005), but importantly there was no significant difference in these influences between the two types of trial (paired T-test on regression coefficients between trial types, all |T(17)|<1.52, all p >0.14).
A highly significant binomial GLMM (χ 2 ML = 33.24, N obs = 196, P < 0.0005; Table 1 ) revealed that, while controlling for the potentially confounding effects of age, sex, group size, the number of zoos a subject had lived in, and task identity, Sumatran subjects were significantly more likely to solve a task than their Bornean congeners (B = 1.934, SE = 0.74, z = 2.63, P < 0.01, Fig. 1 , Table 1 ).
We correlated the tdTomato/YFP ratios with survival time and noticed that infected cells with a shorter survival time tended to be cells with a low ratio of tdTomato/YFP expression (Figure 6 B), and Spearman test resulted in a highly significant correlation index (r = 0.28, p = 0.0005), arguing that LSEC-uniLT that expressed relatively more YFP than tdTomato lysed earlier than cells that expressed more tdTomato.
Both the test for a general birth weight-effect of any kind, and the test for a non-linear effect were highly significant after adjustment for BMI at age seven years (p<0.0005 and p = 0.009, respectively).
PERMANOVA comparisons between each plant-based analogue subcategory and its animal-based reference counterpart revealed highly significant differences across all categories ( p ≤ 0.0005). 3.3.
The difference in TMS and TLS between two groups was also highly significant with P < 0.0005 [ Table 3 ].
Regarding stage group, our study out of 36 resected cases revealed that combined MSH6 & PMS2 loss prevalent in stage III tumors (54.5%), followed by stage II tumors (45.5%), with a highly significant correlation combined markers loss between and III/II stages (p=0.0005).
These differences across the genotypes (SI/SI and SC/SC) for number of days to germinate and percent germination were highly significant (Kruskal–Wallis, P ≤ 0.0005 for both).
A P -value < 0.05 (*) was considered statistically significant, P < 0.005 (**) was considered highly significant, and P < 0.0005 (***) was considered extremely significant.
The most striking impact of dialysis modality was on change in albumin, which was highly significant for PD patients ( p = 0.0005), but not HD patients ( p = 0.34).
In contrast, the correlation between genetic and geographic distances remained highly significant after controlling for temporal variation (r=0.55, Zr=0.55, p<0.0005).
Results showed that there was a strong positive correlation between growth rate and pathogen virulence (as evaluated by relative lesion height), which was very highly significant ( r = 0.817, n = 10, p < 0.0005).
The difference was statistically highly significant (ANOVA, p = 0.0005, F-value = 8.166), indicating a significant inverse relationship between MC count and advancing age (Table 4 ).
Faroese smokers tended to have higher T than non-smokers (p=0.7, adjusted for BMI effect), whereas the effect on the Danish men were highly significant (p<0.0005).
In all cases the change in β was highly significant (p < 0.0005).
Interestingly, there is a marked discrepancy between groups, with points around 200 Hz displaying a highly significant difference ( p < 0.0005; Bonferroni corrected significance is p < 0.0025).
The results of two non-RCTs were additionally combined in an individual patient data meta-analysis, and showed highly significant results (HR: 0.43, 95% CI: 0.34–0.56, p < 0.0005) [ 135 ].
6 ) and PLS-DA model validation by permutation tests was highly significant (p < 5e-04).
Benefit For this case, the global Pearson’s chi-squared values were highly significant ( x 2 = 23430.50, df = 16; p < 0.0005).
The analysis of variance of the mean SGN densities in deafened ears showed highly significant differences both for the total cochlear ( p = 0.0005) and for the basal region ( p < 0.0001) when compared with NH.
However, mice immunised with chromatographically deaggregated hIgG (deag.hIgG) showed a highly significant lowering of the immune response, in comparison to either ag.hIgG (P = 0.0005) or the heat-ag.hIgG (P = 0.001).