“highly significant”

Addition of 5 g ml-1 of anti-ICAM antibody at the 40:1 ratio (Figure 6A) caused a highly significant 1.5-fold decrease in lysis of control C8161 cells (from 16.2% to 10.7%, P < 0.0005).

Upregulated genes grouped into 75 highly significant categories (selected according to p <0.0005 and at least 10 genes per category, S2 Table ), of which 22 (29%) were involved in the development, growth or death of brain cells, functions of the nervous system (e.g., behavior, cognition, or mood disorders) and/or the amount of neurotransmitters ( Table 1A ).

The ANOVA of the data obtained revealed that “age”, “type of emotion”, “stimuli duration” and “gender” factors were highly significant ( p < 0.0005) in the process of speech emotions recognition in the adult sample and the “emotion valence”-within each age group.

Furthermore, changes in responses on the Diabetes Self-Efficacy Scale, the Diabetes Attitude Scale, and the Diabetes Empowerment Scale were highly significant at the 2-month, 4-month, and 6-month posttests at the p < 0.0005 level [ 46 ].

However, a statistically significant difference was observed between the two groups after 30 days (p = 0.0391), with a highly significant difference detected after 60 days (p = 0.0005) ( Table 2 ).

Comparing the categorical variables before and after ablation in AVNRT patients, applying the McNemar-Test we found a highly significant improvement with respect to state of health (p<0.0005) in this large patient group (Figure 3 , Panel A).

The distribution of the prevalence of these strata against age in years is highly significant (χ 2 (20) 106, p<0.0005, Figure 2 ).

The generated explanatory model showed that across all four responses, the highly significant ( P < 5 × 10 –4 ) factors and interactions were the ON/OFF stability (ΔΔ G ) of the anti-RBS-RBS hairpin, the interaction between TIR and hairpin ΔΔ G , TIR, and IPTG concentration ( Supplementary Table 6 ).

While for CD4+ cells the difference was statistically significant only on day 15 ( P <0.005) and 20 ( P <0.05), the difference was consistently observed for CD5 and CD8 positive cells and was highly significant for CD8 + cells ( P <0.0005).

These correlations, although weak (r– 0.17, r– 0.14 and r– 0.24, respectively), were highly significant (p = 0.0005, p = 0.005 and p<0.0001, respectively), ( Table 3 ).

The age adjustment was highly significant (p<0.0005), with an estimated mortality increase of 13.7% (95% CI 7.4% to 20.3%) for each 1% increase in %≥65.

Results showed that there was a strong positive correlation between growth rate and pathogen virulence (as evaluated by relative lesion height), which was very highly significant ( r = 0.817, n = 10, p < 0.0005).

WDSCC showed greater expression of E-Cadherin than MDSCC while PDSCC showed the least expression and the difference was highly significant ( P = 0.0005).

A large prospective study found there was a highly significant relationship between pain and sleep (P < 0.0005), with a 55% increase in the proportion of participants reporting restless/light sleep after chronic low back pain onset [ 2 ].

At the group level, the first of these differences is highly significant by a (classical) matched-pairs t -test, D = 16 ms, t (19) = 4.33, p < .0005, whereas the second of them is not, D = − 3 ms, t (19) = − 1.73, p > 0.05.

However, creatine kinase continued to exhibit a highly significant increase in group [D] vs. group [C] (*** p = 0.0005) (Fig. 5 C-b).

Similarly, highly significant correlations were observed for CD3+ T cells ( p = 0.0005), CD4+ T cells ( p = 0.0012) and CD68+ macrophages ( p = 0.0026) between the infiltration densities in the two different regions.

The results showed highly significant ( p < 0.0005) measures of absolute agreement for all test comparisons [ 9 ].

A highly significant relationship was found between Prm 2 promoter divergence and relative testes size ( r 2 =0.7065, p =0.0005)—independently or normalized in relation to Prm 1 promoter and to the neutral divergence assumed for INT ( figure 3 ; table 2 ).

We identified several highly significant ( P < 5 × 10 −4 ) maternal QTL influencing total body weight, organ weight, and fat pad weights in both sets of subcongenics.

The culprit plaque was acute thrombus, either rupture or erosion, in 45% of patients >40 years versus 68% of ≤40 years; the difference in the rate of erosions (14 versus 36%, respectively) was highly significant ( P = .0005).

Both the test for a general birth weight-effect of any kind, and the test for a non-linear effect were highly significant after adjustment for BMI at age seven years (p<0.0005 and p = 0.009, respectively).

In addition, highly significant loci were detected on chromosome 8 of 320-02 at marker P14M37-134 ( P < 0.0005) and on chromosome 9 of 10618-01 at marker E32M48-233 ( P < 0.0001) (Table 2 ).

Tests of bivariate associations (Spearman's rho) revealed no association between costs to diagnosis and age ( p = 0.623), but as expected, there was a highly significant positive association between costs and number of days to diagnosis ( p < 0.0005).

The Wilcoxon signed ranks test value was negative and highly significant (z = -3.49, p < 0.0005.) Thus, HSAs with pediatric beds tend to have poorer Medicare-pediatric agreement than HSAs without pediatric beds.