“highly significant”

The results of this comparison, shown in Figure 3 , indicate a highly significant correlation (lesions per base: model = 0.9006 × [ΔΔ C t ] + 0.73; r = 0.89, P < 0.0005).

A highly significant negative correlation between changes in mydriasis and pupil size at rest could be observed both on the hypertonic (r = − 0.921, p < 0.0005, Y = − 1.269X − 0.010) and on the hypotonic side (r = − 0.800, p < 0.0005, Y = − 1.399X + 0.09).

The most striking impact of dialysis modality was on change in albumin, which was highly significant for PD patients ( p = 0.0005), but not HD patients ( p = 0.34).

A one-way ANOVA showed a highly significant cohort effect ( F = 14.20, p = .0005, η 2 = 0.69), and a pairwise post-hoc Tukey-HSD test computed with the onset indices for the ND-CI and AD-CI cohorts were not significantly different ( p = .98), but did reveal a significant difference between ND-CI and NH-acoustic ( p = .0007) and AD-CI and NH-acoustic ( p = .0018).

Risk of LE rose across the cardiovascular disease risk scores in a highly significant trend ( p = 0.0005) (see Fig. 1 ).

Results showed that there was a strong positive correlation between growth rate and pathogen virulence (as evaluated by relative lesion height), which was very highly significant ( r = 0.817, n = 10, p < 0.0005).

Results Multiple comparisons using one-way analysis of variance (ANOVA) between the materials on day zero, 45 th and 90 th day was highly significant with p=0.0005.

3C , and revealed highly significant changes as a function of gestational age (p < 0.0005) and mouse model (p < 0.0005).

In an analysis of variance (ANOVA) of absolute abundance of Faecalibacterium quantified by qPCR, with factors subject, presence/absence of tannins, allele at MEL6A, and all interactions between them, all factors were highly significant ( P -value <0.0005) except the interaction term for tannin and MEL6A allele ( Supplementary Table 8 ).

The cortex comprised of 19 brain areas all showed a decrease in brain volume that was highly significant ( p = 0.0005) with a mean difference of −3.195.

The distribution of the prevalence of these strata against age in years is highly significant (χ 2 (20) 106, p<0.0005, Figure 2 ).

A very strong and highly significant association of the biomarkers with the Average Change of the PGI-R was found (adjusted R2 = 0.61, p < 0.0005), with the most significant biomarkers being vitamin K (p = 0.03) and Biotin (p = 0.04).

This effect was highly significant with 95% confidence ( P < 0.0005).

The results of two non-RCTs were additionally combined in an individual patient data meta-analysis, and showed highly significant results (HR: 0.43, 95% CI: 0.34–0.56, p < 0.0005) [ 135 ].

This huge change is both practically important and highly significant statistically ( p < 0.0005 and Cohen's d for the change is 1.07, a large effect size).

This corresponds to a highly significant increase (p = 0.0005).

All radiographic angles showed highly significant statistical difference: HVA decrease from 37.5±8.5° to 21.0± 9.7° ( p =0.0005), IMA decrease from 15.4± 3.85° to 9.4±4.7° ( p <0.0001) and DMAA change from −0.6±7.82° to −3.1±8.45° ( p <0.0001).

1b ) with a 2 × 2 ANOVA showing highly significant effect of LB ( F [1,63] = 14.9, p < 0.0005), with no effect of sex ( F [1,63] = 0.18, p = 0.67), or interaction ( F [1,63] = 0.43, p = 0.52).

In contrast, selection for the BCDO2 locus became highly significant ( s = 0.0060, P = 0.0005) in models without migration, confirming that unaccounted gene flow can cause spurious effects in selection analyses.

Interestingly, there is a marked discrepancy between groups, with points around 200 Hz displaying a highly significant difference ( p < 0.0005; Bonferroni corrected significance is p < 0.0025).

In contrast, the correlation between genetic and geographic distances remained highly significant after controlling for temporal variation (r=0.55, Zr=0.55, p<0.0005).

The difference in apparent body weight gain between the two groups of pups was highly significant (p < 0.0005; n = 18; Figure 1c2 ; Table S4 ).

The fitted model was highly significant ( p = 0.0005 and F = 6.77).

The AEC 220/μL cutoff classified the patients into two populations with highly significant different distributions ( p = 0.0005, Figure 1E ).

GAG from OA had a highly significant ( P = 0.0005) decrease in S% (1.79% ± 0.25%), as compared to fracture samples (2.3% ± 0.19%), with an associated and significant ( P = 0.0001) reduction of the zeta potential in the OA group.