“highly significant”

However, since significant terms were highly significant ( p <0.0004 in all cases) and non-significant terms were highly non-significant ( p >0.1259 in all cases), there is no ambiguity in the results.

MMSE found a highly significant improvement in Delayed Verbal Recall (p=0.0004).

We point out that the MCD index for the LC → Fz is generally lower overall that the other pathways ( Table 4 ), though still highly significant ( p = 0.0004) at the group level.

A highly significant difference was found in mean Vitamin D levels between cases and controls ( P = 0.0004).

The levels of VLDLR-AS1 were lower in the rmTBI samples compared to the no lifetime TBI samples, and this difference was highly significant ( p = 0.0004), indicating that VLDLR-AS1 is a strong, viable indicator of rmTBI.

At the end of 12 weeks, there was a highly significant ( P = 0.0004) 20 m placebo-corrected median improvement in 6MWD.

Differences in patient satisfaction between women having answered this question with “yes” or with “no” are highly significant ( P < .0004).

The difference in the two distributions is highly significant (Fisher's exact test, P = 4×10 −4 ), suggesting that ethnic differences contribute to the bimodal distribution of imputation quality seen in Figure S12 .

Imaging findings There was a highly significant difference between both groups in the context of lung congestion in X-ray with more congestion profile in COVID-19 patients ( p = 0.0004).

This difference in uptake between [ 18 F]-FACBC and [ 18 F]-FET was highly significant for the MM.1S ev/ev xenograft tumors ( p = 0.0004).

The PCC for H10 results was 0.52, but also highly significant ( P <0.0004).

Peptide:MHC (pMHC) tetramer staining revealed a significant expansion of T cells specific for the acute, non-inflationary immunodominant epitope M45 (p = 0.0004), with smaller, but also highly significant expansion of CD8 T cells specific for inflationary epitopes m38 (p = 0.0004) and m139 (p = 0.0004) ( Fig 2E ).

While the deletion of Grk1 slowed the recovery of responses driven by both pigments, the effect on the M-pigment response was much larger; thus, in the absence of Grk1, the average Δ T 50 of the response to the M-pigment increased 7.5-fold (from 0.33 to 2.44 s), while the Δ T 50 of the UV-pigment response increased 2.8-fold (from 0.25 to 0.69 s); both these differences in Δ T 50 are highly significant (P < 0.0004), arguing strongly that Grk1 is necessary for normal inactivation of both pigments.

Responses to the QuickDASH instrument in each study group expressed highly significant values ( p < 0.0004 and p < 0.0001) in each of the QuickDASH assessment sessions.

Furthermore, if one defines any performance either above or below two standard deviations of the control mean as unusual for each measure, the difference between the number of “unusual observations” for the ASD group and controls was highly significant (median ASD = 8.0; median controls = 3.0; U = 83.5, p = 0.0004).

As shown in Figure 1a , the difference in overall distribution of tetramer positivity was highly significant between groups ( P <0.0004) and, with two exceptions, all the VNTR III/x subjects were at or near background levels of tetramer detection.

We found within each section highly significant volume reductions in depressed compared to controls (Input p = 0.0004 (eta 2 = 0.07), Middle p = 0.0002 (eta 2 = 0.09) and Output p = 0.0004 (eta 2 = 0.06)) suggesting that MDD impacts each part of the central circuit pathways across the hippocampus.

CfMYB2 (Figure 4E ): A significant main effect of both cultivar ( F = 10.04, p = 0.0012) and stage ( F = 5.21, p = 0.0164), as well as a highly significant cultivar × stage interaction ( F = 8.79, p = 0.0004), was observed for CfMYB2 expression.

There was a highly significant improvement in symptoms: the validated Pregnancy-Unique Quantification of Emesis (PUQE) 13 score improved from 14.5±1 to 7.5±0.58 ( P =0.0004).

A meta-analysis in 2002, which used data from 18 trials and 2074 patients, indicated a highly significant reduction in the risk of death with NACT (HR 0.65, 95% CI 0.53–0.80, P = 0.0004) [ 14 ].

Specifically, the partitioning around medoids (pam) clustering algorithm [ 29 ] with two centers predicted one cluster with 52 good outcome and 56 poor outcome patients, and another cluster with 56 good outcome and only 19 poor outcome events, which was highly significant under Fisher's exact test ( P = 0.0004; Figure 3c ).

Dogs receiving polytherapy have a highly significant increase in shaking, shivering, or trembling when left or are about to be left on their own when compared to dogs on monotherapy (question 22, P = 0.0004).

Comparison of incidence rates for grouped skin types (group 1 = skin types 1 + 2, group 2 = skin types 3–6) showed a highly significant difference ( p = 0.0004, incidence rate difference − 1:7) with an incidence rate of 1:53 (95 % CI 1:438–1:15) for group 1 and 1:6 (95 % CI 1:10–1:4) for group 2.

In contrast, when we analyzed the striatum and the ventral forebrain of intraparenchymally grafted animals versus vehicle-injected controls, we observed highly significant 7-fold (p = 0.0004 ) and 35-fold (p = 0.0001 ) reductions in CD68 immunoreactivity, respectively.

First, the total relationship between Personal Distress and conformity was highly significant (the coefficient for path c = 0.0259, z = 0.00761, P = 0.0004), indicating that increased conformity is associated with more anxiety.