“highly significant”

Our results revealed highly significant synergistic genetic interactions between neb and polo for both symmetric cell divisions and earlier cell divisions ( P = 3.89 × 10 −4 and P = 1.00 × 10 −6 , respectively), but no significant interactions in the case of asymmetric cardiac progenitor cell divisions ( P = 0.117) (Figs. 5 a,d,e, 6 b, Supplementary Table S1 ).

The DRD2 (Dopamine receptor D2)-variant (rs6277) was highly significant where the C-allele displayed a protective effect towards overweight development (OR: 0.79, 95% CI: 0.69–0.90, P = 3.9x10 -4 , adj.

In addition, similar and all highly significant ( p ≤ 3.9 × 10 −4 ) Pearson correlations were found between all three housekeeping genes; GAPDH, HBB, and ACTB, for all collection volumes ( Figure A3 ).

Dogs receiving polytherapy have a highly significant increase in shaking, shivering, or trembling when left or are about to be left on their own when compared to dogs on monotherapy (question 22, P = 0.0004).

The difference between the groups at T12, as well as the difference between the relative changes in skin hydration of both groups proves to be highly significant ( p < 0.0004) in favor of the test product.

AA) further supported this finding, showing a highly significant risk elevation (OR = 2.85, P = 0.0004), and the MTHFR C allele itself exhibited the strongest allelic association observed (OR = 2.17, P = 0.0004).

The PCC for H10 results was 0.52, but also highly significant ( P <0.0004).

For the primary motor outcome, the MDS-UPDRS Part III, the LMM revealed a highly significant main effect of Time (F(2,36) = 9.54, p = 0.0004), indicating overall motor improvement in both treatment groups.

Highly significant ( p ≤ 0.0004) quantitative differences in mean DN/P SI ratio were noted for all groups in which visible T1-hyperintensity was noted.

While men with elevated T had higher HDL ( P = 0.0003), the findings for partnered RC again remained highly significant ( P = 0.0004) but with a decrease in effect size (model not shown).

This difference was highly significant ( P = 0.0004); the average distributions were 64% ±17 gametocytes in the BM and 8% ±9 gametocytes in the PB (Fig. 3b ).

Self-reported engagement in muscle-strengthening exercise showed a similar pattern, with highly significant differences at all three follow-up times (p=0·0004, p=0·0004, and p=0·0006).

A meta-analysis in 2002, which used data from 18 trials and 2074 patients, indicated a highly significant reduction in the risk of death with NACT (HR 0.65, 95% CI 0.53–0.80, P = 0.0004) [ 14 ].

In our comprehensive analyses of 1422 TCS with state-of-the-art audiologic testing, cisplatin showed a highly significant dose-response relationship with hearing loss (p = 0.0004).

The ER expression of adenomyotic foci in relation to functional and nonfunctional ovarian cysts was statistically highly significant ( p =0.0004).

Despite the small sample size included in the database for this tissue ( n = 72), also in this case, the analysis highlighted a highly significant association ( P = 4 × 10 –4 ) between rs7164338 and CIB2 expression levels.

2c–e ) and found that female mice showed a highly significant decrease in SI3 (Fig. 2e : t = −3.8, p = 0.0004 for females, compared to t = −1.2, p = 0.23 for males).

Bonferroni-corrected post hoc paired T -tests revealed a highly significant difference between fluent and nonfluent ABM sequences for body stimuli ( t (23) = 6.3, P < 0.0004), but the corresponding difference for nonbody stimuli just failed to achieve significance ( t (23) = 2.7, P = 0.052).

Age had a highly significant association with reported keloid cases per million VMMCs performed, at p = 0.0004, with 1.09 vs 0.05 keloids reported for every million VMMCs performed among clients aged < 15 years and ≥ 15 years respectively.

The levels of VLDLR-AS1 were lower in the rmTBI samples compared to the no lifetime TBI samples, and this difference was highly significant ( p = 0.0004), indicating that VLDLR-AS1 is a strong, viable indicator of rmTBI.

The model to optimize the AzA-TEs was highly significant ( p -value = 0.0004) ( Figure 1 E,F).

Results: The results of this screening study showed that ADHD is highly significant associated with gender (p = 0.0004).

Mirtazapine was also a highly significant suppressor of the histamine response when evaluating median wheal size for monotherapy compared to controls ( p = 0.0004) (Table 3 ).

Conversely, the use of CL4-PNPs as a delivery vehicle for Cis-Pt, resulted in a highly significant inhibitory performance on tumor growth compared to free Cis-Pt ( P = 0.0004) and Cis-Pt@PNPs-SCR (P = 0.0009) (Fig. 6 a).

The interaction effect between diabetes and FBG was highly significant (p = 0.0004), and we therefore performed separate analyses for patients with a diagnosis of diabetes and for those without.