“highly significant”

As shown in Figure 1 A, in recipients of HLA-matched HSCT with at least one C1 group allele (i.e., C1/1 or C1/2; n = 634), ATG was associated with a non-significant survival advantage in the unadjusted univariate analysis, but with a highly significant advantage (RR, 0.52; p = 0.0003) in multivariate analysis, adjusting for the most relevant confounding factor, unrelated donor.

, both semi-conserved and variable) was highly significant ( p < 0.0003), indicating that variable SBMCs showed a strong bias for location towards the ends of chromosomes (Fig. 5 ).

On day 7, there was a highly significant difference among instruments ( p = 0.0003), with the laser showing higher scores compared with the electrosurgical scalpel ( p = 0.0054).

Compared to controls, PD exhibited a significant decrease in neuronal estimates ( p = 0.017), a decrease in astrocyte estimates ( p = 0.01), and a highly significant decrease for endothelial cell estimates ( p = 0.0003).

The test for moderators was highly significant (Q M = 20.99, df = 4, p = 0.0003), and the model successfully explained 66.9% of the total heterogeneity.

Therefore, the number of RoH segments in the landlocked population is approximately 1.9–7.7 times higher than those of the anadromous salmon populations, and the differences between them were highly significant (at least, P = 0.0003).

Kaplan–Meier analyses demonstrated highly significant associations between high histoscores for cytoplasmic and nuclear phospho-eIF4E and reduced survival in all patients ( P =0.0003 and 0.0009, respectively).

The effect of claw on the variance of the difference between the two measures was highly significant (−2LL difference 48.2; df.18; p < 0.0003).

Statistical comparison of the neutralising immune response elicited by VXB-221 to comparator hMPV F DSCavEs2 showed a highly significant difference (Mann Whittney Test; p = 0.0003).

The increase of aversive behavior in response to the visual cue was highly significant in Mela(CTmGluR6)-treated ( p = 0.0003) and C57BL/6 mice ( p = 0.0026), but no behavioral change in response to the drifting stimulus was seen in untreated rd1 littermates ( p = 0.83, Fig. 7b ).

This represented a highly significant increase not only compared to the precursor clarified RBC hemolysate ( p = 0.0003) but also when compared to the RBC enzyme cocktail fraction ( p = 0.0067).

There was a highly significant subretinal treatment effect on ERG amplitudes collectively at 7–9 months post-injection (p = 0.0003).

The PET/CT result was a highly significant predictor of OS (Hazard Ratio [95% Confidence Interval] =4.7 [2.0-10.9] for PET positive versus PET negative for a systemic recurrence; p = 0.0003).

When the analysis was performed using only infected herds located in the high risk area (n = 60), incremental spatial correlation analysis of the log-transformed βs revealed the occurrence of highly significant positive autocorrelation (p = 0.0003–0.036) between 6 and 14 km distance with a peak at 12 km ( Fig. 2 ).

The Pearson correlation test showed a highly significant correlation (r = 0.83; P = 0.0003).

After one week of SFOH intake, a highly significant increase in Fe(2+) and Fe(3+) was observed in the patients' stool supernatant (p = 0.0003 and p = 0.0085, respectively), which then decreased by week 4 (t2, V2, endpoint of the study), but was still significantly higher (p = 0.0028 and p = 0.0424) than at baseline t0 (Fig. 6 ).

Importantly, a highly significant (p = 0.0003) reduction of CD19 + IL21R − TLR4 + B cells after food intake was observed with increasing BMI in the subjects.

Compared to homozygous common allele carriers, heterozygous for the T variant were found to be at a highly significant 5.59 -fold increased risk of developing endometrial cancer (95 % CI = 1.96–15.91; p = 0.0003).

Figure 6 illustrates significant changes obtained for a number of atlantoaxial linear parameters based on the total sample of patients, including significant changes for Chamberlain by 0.93 mm ± 2.58 mm (p = 0.0055) and highly significant changes for CVT (p = 0.0003), OPT (p < 0.0001) and Redlund-Johnell/Petersson (p < 0.0001).

Correlation of absolute against normalized hormone concentrations was highly significant for both cortisol and melatonin (cortisol: Pearson’s r = 0.8238, p = 0.0003; melatonin: Pearson’s r = 0.7564, p = 0.0001).

Regressing the ADOS severity score on the percentage of MSA in the retelling task produced a high value for the coefficient of determination ( R 2 = 0.85) and highly significant goodness of fit results ( f ‐ p value = 0.0003).

In group G4, the improvement was more pronounced and also highly significant ( p = 0.0003).

other) was highly significant [ F (1, 16) = 20.49, p = 0.0003], while the effect of experiment (1 vs. 2) was not significant [ F (1, 16) = 0.38, p = 0.55], and there was no interaction between these factors [ F (1, 16) = 0.06, p = 0.81].

In order to define an appropriate drug concentration, tetracycline response experiments were conducted, whereupon embryos infected with 1500 CFU SH1000 EryR (GMSA015) were immersed in sterile E3 medium containing a range of antibiotic doses for the duration of the experiment ( Figure S3A ).While 50 μg/ml tetracycline produced a highly significant, curative response ( p = 0.0003), 10 μg/ml tetracycline showed a trend towards curing ( p = 0.0753) and 5 μg/ml was entirely sub-curative ( p = 0.2181).

Interestingly, we found a highly significant interaction effect between Distribution Type and Standard Vowel [ F (1,18) = 20.22, p = 0.0003, η p 2 = 0.53], which shows that the attested difference between unimodally and bimodally trained Dutch 2-to-3-month olds differs depending on the standard that they hear in the oddball test (see section Exploratory Results for the Four Groups).