“highly significant”

When contrasting extreme group individuals, that is, those with 1.5–2.5 to those with 5.5–6.5 proautistic genotypes, a highly significant difference ( P = 0.0002) regarding severity of autistic features emerged (Fig 4 C).

The difference between the 2 groups was highly significant ( P < .0002).

At the lower dose of sucrose and higher dose of OLE, a highly significant decrease ( p < 0.0002) in peak glucose was observed in all individuals (Fig. 8 ).

More precisely, a clear differentiation in the overlap type groups is evident, as both F-tests and P-tests [32] are highly significant (for F -test: p<0.0002; for P-test: p<0.001) which is further supported by the high bootstrap values obtained between the clades ( Figure 2 and Figures S1 and S2 ).

3C–F ; the decrease was highly significant in the lung ( P = 0.0002) and almost achieved significance (p = 0.069) in the heart).

These curves clearly show that while thirds of IL-6 showed little discriminative ability in separating risk for nonfatal CVD in unadjusted models ( p = 0.13), associations with risk for fatal CVD events, fatal other CV events, or non-CVD mortality were all highly significant ( p ≤0.0002 for all).

For instance, the genus Clostridium exhibited the highest mean relative abundance in the high Ca treatment (V), with highly significant differences ( p = 0.0002) compared to the control (K) and most other treatments.

9 , bottom row); these differences were significant for all groups including the LVS Δ capB vector in experiment 1 (ranging between P < 0.05 to P < 0.01) and for all but the parental vector and one vaccine in experiment 2 (ranging from P < 0.05 to P < 0.0001); combining all LVS Δ capB and r LVS Δ capB /Bp vaccines, the increase in antibody to HI Bp82 was highly significant ( P = 0.0002 and P < 0.0001 by two-tailed t test in experiments 1 and 2, respectively).

Number of ChAT- and TrkA-ir Neurons in L1 Tau Mice Differ from the Wild-Type Controls For interneurons in NAc, a factorial two-way ANOVA with the genotype and treatment for the core groups confirmed the highly significant main effect of the genotype (F(1,31) = 18.2; p = 0.0002).

Two-way ANOVA revealed an extremely significant effect of OPI-T dose ( p < 0.0001), a non-significant main effect of palmitate ( p = 0.4701), and a highly significant interaction between the two factors ( p = 0.0002), indicating that the antioxidant effect of OPI-T is strongly dependent on its concentration and is particularly evident under lipotoxic conditions, showing an antagonistic interaction with palmitate.

miR-125a-5p showed a highly significant association, with a genetically predicted increase in expression associated with a 26% reduction in AD risk (OR = 0.74, 95% CI: 0.64–0.87, P=2.05e−4).

Overall, the Leu372Val substitution had a highly significant effect on surface expression (ANOVA, p = 0.00021), while there was no effect ascribable to the Thr357Ala replacement (p = 0.579).

As discussed in Results , the identification of 10 of 54 genes with a link to HIV-1 replication is a highly significant over-representation (p value<0.00021) over the expected number (2.4) in randomly generated lists of 54 genes that are expressed in both Jurkat and MM6 cells.

The findings demonstrate significant variances between stage I and II ( P = 0.027), highly significant variances between stage I and III ( P = 0.00021), and extremely significant variances between stage I and IV ( P = 0.0054).

For Model 1, the fit was highly significant (t(54) = 3.98, p = .00021), whereas the fit for Model 2 only bordered significance (t(54) = 1.88, p = .066).

We found that FoxC1-induced genes were enriched among native SGCs relative to ECs, and that this enrichment was highly significant ( P = 2.1 × 10 –4 ).

Instead, there was a highly significant relationship between serum IFN-α and LRRC20 genotype in a joint analysis of European- and Hispanic-American subjects ( P = 2.1 × 10 -4 ), in whom the serologic association with anti-La antibodies was not present (Supplemental figure S2 in Additional file 1 ).

The difference between the two groups was highly significant ( p = 0.00022), with a mean difference (−1.801 kcal/mol) substantially exceeding the inherent noise level of the scoring protocol.

Since duration apparently influenced the success of mountings, we tested for an effect of location and found a highly significant male species × female species × location interaction (χ 2 = 18.89, df = 1, P = 0.00022), driven mainly by short interspecific matings in the sympatric, but not in the allopatric combinations (Fig. 1 A).

For example, the protective effect of CCBs on dental caries risk in the FinnGen cohort remained highly significant in the MR‐PRESSO analysis (OR: 0.9709; 95% CI: 0.9503–0.9837; p = 2.23 × 10 −4 ) reinforcing the validity of our primary findings. 3.3.

Moreover, highly significant differences were identified for the eraser FTO ( P =2.257x10 -4 ), the strongest obesity candidate gene identified in genetic studies ( 19 ).

The fit of the log–logistic model ( eq 2 ) was highly significant ( p -value = 2.27 × 10 –4 ) and resulted in a EC 50 value of 3.57% sediment dw (±3.22) and an EC 10 value of 1.07% ( SI Figure S3 ).

6 expected), supported by a highly significant PPI enrichment value ( p = 0.000228).

Water regime under salt stress and QuitoMax application The differences in the water potentials of the varieties in the different treatments were highly significant [F = 108.5; p = 0.00023, F = 112.46; p = 0.000321 for Amalia and Claudia, respectively (Fig. 2 a and b)], and a similar response was found for the osmotic potential (F = 207.32; p = 0.00461, F = 201.31; p = 0.00117 for Amalia and Claudia, respectively).

The trend to increased cataract score with age was highly significant ( P = 2.3 × 10 −4 ).