“highly significant”

The second strongest signal identified in the GWAS, observed at rs12506228, showed two independent replications and the meta-analysis for replication studies was highly significant ( p = 2.0 × 10E-4).

Homogeneity of variance (or dispersion) was tested using PERMDISP and was highly significant from homogeneity of variance ( P = 0.0002).

Results All studies showed a positive correlation between carotenoids and retinol, which was overall highly significant ( r = 0.50, P = 0.0002; Fig. 2 ; without apparent publication bias: rank test, P = 0.36 and funnel plot inspection).

Furthermore, the interaction between baseline FS and treatment arm is highly significant ( P =0.0002; Table 2 ).

The differences between the populations are highly significant for both Cmax values, as determined by 3-group permutation ANOVA (p < 0.0002 for both) and pairwise Wilcoxon test for sparse vs dense (p = 2e-18 and p = 9e-14 for Cmax = 90 nM and 900 nM, respectively).

One is that advanced stages (RAEB and RAEB-t) had a highly significant association with the frequency of abnormal karyotypes ( P < 0,0002), evolution of disease ( P < 0,0001), and mortality ( P < 0,0005).

For instance, the genus Clostridium exhibited the highest mean relative abundance in the high Ca treatment (V), with highly significant differences ( p = 0.0002) compared to the control (K) and most other treatments.

The PRC diagram (highly significant, pseudoF = 52.3, p = 0.0002, Fig. 5 ) clearly demonstrated the responses to experimental manipulations.

In general, the difference in CYP2W1 expression between normal tissue and primary tumours was highly significant (P ≤ 0.0002).

Given the fraction of total axis length that was asynapsed in these syp-1 RNAi mnT12 nuclei, the observed restriction of GFP::COSA-1 foci to synapsed segments (where homologs are closely juxtaposed) represents a highly significant (χ 2 test; p = 0.0002) departure from the distribution expected if GFP::COSA-1 foci were equally likely to occur on synapsed segments and asynapsed segments (where homologs are separated), consistent with the interpretation that these GFP::COSA-1 foci correspond to interhomolog recombination events. 6 Extended Data Figure 4.

These results were corroborated by PERMANOVA, which confirmed no significant difference between the two rhizosheath communities (Permutation tests, R = 0.256, p = 0.089) but a highly significant difference between the rhizosheath and bulk soil communities (Permutation tests, R = 0.9, p = 0.0002) ( Figure 4 a,b). 2.3.2.

For the Ncl window (240–285 ms), a highly significant main effect was found for condition ( p = 0.0002) and group ( p = 0.039) with higher GFP for the IC condition and in the group with 22q11.2DS.

With the exception of the consumer price index, all the nominally significant variables displayed in Text S1 (Table A) remained highly significant (P<0.0002 or lower) after Bonferroni correction for multiple testing.

Indeed there is a highly significant correlation between urinary glucose and the glucose tolerance test area under the curve (r=0.623, p=0.0002), a measure of insulin resistance not directly influenced by food intake.

Results and Discussion Metabolites and isotopic signatures With increasing CH 3 F concentration, acetate accumulated while methane accumulation was reduced accordingly ( Figure 2A ) resulting in a highly significant negative correlation (r = 0.7, P = 0.0002).

This is also confirmed by the results of the ANOSIM test, wherein there was a strong and highly significant difference in assemblage composition among habitat alteration types (ANOSIM R = 0.759, P = 0.0002).

After correcting for multiple statistical tests on the same data, the difference between 0 and 24 hp irradiation in the signal intensity within the host DNA was not significant (F = 3.1; df = 1, 123; p-value>0.16), whereas the difference between 0 and 24 hp irradiation in the signal intensity in the virus DNA was highly significant (F = 64.5; df = 1, 109; p-value<0.0002).

A highly significant (P = 0.0002) increase in the rate of malsegregation affecting structurally normal chromosomes was observed in association with Robertsonian translocations.

1b ) revealed highly significant correlations of PC1 and PC2 with hepatic zones (PC1: r = 0.47, p = 2.0 × 10 −4 ; PC2: r = 0.86, p < 2.2 × 10 −16 , Supplementary Figure 3) indicating zonation as a major driver of variation between samples.

The interaction between intruder x resident genotype was also highly significant (F 2,40 = 10.71, p = 0.0002).

In contrast, hypertensive patients exhibited markedly higher concentrations, averaging 3.0 ± 0.7 ng/mL, and this difference was highly significant ( p = 0.0002).

When the tumour volumes at day 4 post-treatment were compared to untreated tumour volumes at day 4, there were highly significant differences (p < 0.0002) at all doses (Table 1 ).

The LMM over HbO revealed both a highly significant main effect of Condition ( F (2, 437) = 8.59, η p 2 = 0.04, p = 0.0002), indicating that overall activations differed across Speech, Song and Hummed melody, as well as a significant Condition × Trial interaction ( F (2, 438) = 4.61, η p 2 = 0.02, p = 0.0104) (Fig. 4 ), indicating different trends between conditions across the time course of the experiment.

Using these 18 donors, the difference between 80% neutralization titers obtained for USHIV+ using bulk versus NK-depleted PBMC was highly significant (Wilcoxon rank, p=0.0002), demonstrating a substantial impact of NK cells on PBMC neutralization titers.

8 ), and this difference was highly significant ( N =16; t=4.87; P =0.0002).