“highly significant”

The analysis across all 673 loci yielded highly significant differentiation ( p << 10 −4 ) between pairs of superpopulations.

We found not only a highly significant difference between the two groups (p ****<0.0001; Fig. 2 I) but also an excellent receiver operating characteristic (AUROC 0.9955; 95% CI [0.9854–1.000]; ****p < 0.0001; Fig. 2 J). 3.2.

In Group I, glycerophospholipid metabolism exhibited highly significant differences ( p < 0.0001), and significant differences in ether lipid metabolism, vitamin digestion and absorption, and fat digestion and absorption ( p < 0.05, Figure 2 g).

Fisher's Exact Test indicated a highly significant association between screening modalities and biopsy findings ( p < 0.0001).

It was 0.991 (187.545, p < 0.0001) for a* , with a highly significant effect of broccoli (246.62, p < 0.0001), IF (134.344, p < 0.0001) and BSG*IF (25.77, p = 0.004).

The relative risk of each stage by sex (women/men) was: Stage 1 , 0.72 (more in men); Stage 2 , 1.11; Stage 3 , 1.68; and Stage 4 , 9.29 (all three more in women); these sex-differences were highly significant (overall χ 2 [d f = 3] = 51.3, p < 0.0001).

According to Table 3 , the model was highly significant ( P < 0.0001), and the lack of fit was not significant ( P > 0.05), which indicated that the regression equation was a good fit and the selected model was appropriate.

A highly significant treatment effect was detected for the discrimination index (F(2, 21) = 157.2, p < 0.0001, R 2 = 0.9374).

A strong and highly significant knock-down of expression ( P < 0.0001, n = 12) was detected 3 days post-agroinfiltration ( Figure 5 ).

Utilizing a custom microarray the correlation ( r = 0.87) between DIM and E 2 in modulation of hepatic gene expression in trout was highly significant ( p < 0.0001) ( 83 ).

On the treated, right (ipsi-lateral) hind paw, the CFA-treatment induced a highly significant increase in pain sensitivity on the first experimental day, MWT dropped to 2.96 ± 0.052 g ( p = 0.000101).

Expression of the NT5C2 allele in phase with the ch10_104957618_I risk allele was also reduced in all assayed adult brain regions (mean DLPFC: 15%, hippocampus: 12%, caudate: 13%), with highly significant differences in allele ratios observed between cDNA and genomic DNA that survived Bonferroni correction in all areas (DLPFC: P = 1.03 × 10 −4 , corrected P = 0.003; hippocampus: P = 2.64 × 10 −6 , corrected P = 8.46 × 10 −5 ; caudate P = 8.11 × 10 −5 , corrected P = 0.0025).

The corresponding F is highly significant (F= 7.34, df= 208, 211, p= 0.0001059), showing that the patient group differs considerably from the healthy volunteer group.

These differences were highly significant when considering qPCR results of PMA vs. non-PMA samples in a paired t test ( p = 0.000106).

Conversely, motif analysis of the repressive H3K27me3 peaks exhibited a strikingly uniform and highly significant (Adjusted p = 0.000106) enrichment of the Helicase-like transcription factor (HLTF) motif, which was present in over 85% of the target sequences ( Supplementary Figure 3B ).

The association analysis of ARDS and COVID-19 fatality rates showed a highly significant value ( p value = 0.000106022666010979).

Upon exploring protein-protein interactions between the 92 DE ExclusiveMS genes using STRING, a highly significant enrichment for PPI was identified ( P = 1.07 × 10 −4 ; Figure S2 ), indicating that these genes act together or respond in concert to detrimental mechanical stress.

0 controls), but the association signal remained highly significant, with a much higher odds ratio (OR = 27.68 [95% CI 1.5–528.7], P = 1.08 × 10 −4 ) (Table 3 ).

Thus, the hot-spot mutations in SARS-CoV-2 were enriched within IRs loci and this association was highly significant statistically ( P -value = 0.0001085; t = −5.94, df = 9, one-sample t -test) ( Figure 1 ).

Regression analysis for the observable t h and independent variable t policy1 yields a highly significant linear correlation (p-value = 1.09 ⋅ 10 −4 ).

For both orientation and numerosity sensitivity, the correlation with mathematics scores was highly significant in the adult group ( R = −0.26, P = 1.1 × 10 −4 ; R = −0.26, P = 1.2 × 10 −4 ; N = 216), confirming that the relationship between numerosity sensitivity and mathematics is not restricted to childhood ( Halberda et al., 2012 ).

Of the 22 genes in the immediate neighborhood of ApoE , including ApoE itself, 4 (18.2%) were inferred as differentially connected between the wild type and ApoE −/− crosses, and this proportion was highly significant (∼8.1 fold enrichment, FET p -value<1.1×10 −4 , permutation adjusted p -value<0.001) ( Figure 5 and Figure S5C ).

The model of the second multiple logistic regression had a highly significant ( p = .00011) moderate capacity (Nagelkerke R 2 = .412) to predict the program outcome (favorable outcome: 86% correct; unfavorable outcome: 70% correct; global: 78% correct).

TG to HDL cholesterol ratio was also a strong and highly significant predictor (β = –9.9, P = 1.1 × 10 –4 ) (model 2), although this relation was attenuated with inclusion of current BMI (model 3).

Only the Rh5 SNPs 439 and 442 were highly significant, p = 0.00011 (see Additional file 5 ) and remained significant after a Bonferroni correction.