As this effect had only borderline statistical significance, and was not important for interpreting the results, it was collapsed and the analysis was re-run The main factor Group was highly significant, F (1,35) = 25.7, p <.0001, r 2 = .021, as well as the main factor Level, F (1,35) = 656.7, p <.0001, r 2 = .93.
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Age ranged between 2.0 and 5.2 years in the animals from the low-fluoride areas and between 1.6 and 13.3 years in those from the high-fluoride area ( Table 2 ) The difference in bone fluoride concentration between the two groups was highly significant (p < 0.0001), whereas no significant difference existed for age (p = 0.12) ( Table 2 ).
The correlation between model predicted and empirical results was highly significant (P<0.0001), with an R 2 of 0.53 ( Figure 4B ).
This trend was highly significant (P<0.0001), and also significant at each schedule point (Table 2 ).
For example, the empirical dataset had 10‐fold more loci than expected with an F ST = 1, which was highly significant compared to expectations derived from the neutral model (computed from simulated distribution in GppFst ; p < .0001).
For the remaining data, we observed a highly significant effect of interaural correlation on ITD thresholds ( F (1,19) = 30.25, P < 0.0001).
The effect of the choice of parameter set on the number of backbone hydrogen bonds, the number of native backbone hydrogen bonds, the polar and nonpolar SASA, the radius of gyration, RMSD 100 , and the proportions of α-helix and β-strand was highly significant, with p < 0.0001.
Rat control on the farm A highly significant difference (χ 2 = 33.4543 p < 0.0001) was observed in the number of T. gondii positive animals among the properties that use cats for rat control (n = 239; 20 positive animals; prevalence 1.73%) and those that do not use them (n = 885; 12 positive 1 animals; prevalence 1.03%).
However, these results demonstrated a highly significant association between cattle origin and bTB prevalence ( p < 0.0001 ), with the odds of infection being 15.0 (95% CI: 3.1–268.7) and 11.7 (95% CI: 2.4–211.9) times higher in Touboro and Mbaiboum, respectively, compared to Banyo (reference locality).
Patients in Arm A demonstrated significant improvements in clinical scores compared to baseline, with highly significant differences at 6, 12, 24, and 36 months ( P < .0001).
Around half (48%) of the cases had psychosocial stress, whereas 82.7% of controls had some form of psychosocial stress and this difference was highly significant ( p = 0.0001).
Over-representation analysis (ORA) of these lists, performed using the Web-based GEne SeT Analysis Toolkit ( http://www.webgestalt.org ) [ 33 ], demonstrated a highly significant enrichment ( P < 0.0001) of the cell component gene ontology category “mitochondrion” for let-7c-5p and miR-155-5p downregulated targets, with a cluster of 26 and 8 genes, respectively (Tables 1 and 2 ).
In this prospective cohort study of 11 G-CSF mobilized allogeneic sibling donors, there was a highly significant rise in PB [CD34 + ] and [CD34 + CD38 – ] throughout day 4 ( P <0.0001), but no reductions in the morning of day 5, as might be expected with a circadian rhythm pattern.
Results: The AD group showed a highly significant cognitive decline (MMSE: 23.2 ± 4.1 vs. 28.2 ± 1.4, p < 0.0001).
Statistical significance was defined as p < 0.05, while highly significant results were defined as p < 0.0001.
The difference is highly significant ( P < 0.0001).
In these additional analyses, the difference in GCV frequencies between WT and PARP−/− cells at the IgL locus remains highly significant ( p <.0001 and p = .0006, respectively), although the number of mutations scored at the less well defined IgH locus was not sufficient to reveal a significant difference in these more conservative analyses ( p = .1023 and p = .1280, respectively).
vexans was found (p = 0.95); however, highly significant differences were found between the mean OMS temperatures for Cx . pipiens and Cx . quinquefasciatus , and Ae . vexans and Cx . quinquefasciatus (both p<0.0001).
Pairwise F ST among the five apricot clusters were all highly significant ( P < 0.0001; Table 4 ).
A consistent decline in the number of AK lesions from day 3 to day 29 was observed for all three active treatments, and the difference between active treatments and vehicle was highly significant at day 57 ( p <0.0001) [ Table 1 ].[ 11 ] The severity of local skin reactions in the active treatment groups followed a dose-dependent pattern, peaked between days 3 and 8 then largely resolved by day 15.
There was a highly significant increase of 40% (relative risk (RR): 1.4; [1.27, 1.55]; p < 0.0001) in admission rates in the female children’s and the adolescents’ group (RR:1.32; [1.24, 1.41]; p< 0.0001) between the pre-COVID-19 and peri-COVID-19 periods in 2019 and 2021, respectively.
3 , are highly significant ( P < 0.0001 by χ 2 analysis).
The treatment effect was initially large, although after adding studies with large sample sizes, the confidence interval narrowed, and the treatment effect became smaller and stable, albeit the treatment effect was still highly significant (P<0.0001).
The results of the regression and variance analysis indicated that the regression model was highly significant ( p < 0.0001), while the lack of fit was not significant ( p > 0.05), suggesting a good model fit.
In all cases, the differences between phenotype classes were highly significant ( P < 0.0001).