The overall prevalence of hypovitaminosis D was 61% [95% CI: 46% to 71%] with highly significant heterogeneity ( I 2 = 99.72%; p < 0.0001).
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The highly significant levels of the models ( P < 0.0001), not significant “lack of fit” ( P > 0.05) and desirable determination coefficients ( R 2 ≥ 0.9754) suggested that both the built mathematical models were precise and applicable.
All correlations were highly significant (P<0.0001).
A reduced cubic model resulted in the best fit of the data which was highly significant (p < 0.0001) with a non-significant lack of fit (0.0688).
A highly significant positive correlation was evident between TSH and creatinine (r=0.72, p <0.0001).
We assessed the extent of increased gene expression from invasive, metastatic, or EMT signatures but failed to see any highly significant correlation (p < 0.0001).
Statistical analysis confirmed the highly significant superiority of CINPs (∗∗∗∗ p < 0.0001).
ANOVA results indicated highly significant differences (P < 0.0001) among mapping individuals (RILs) for all three traits despite significant environmental (years) effects on these traits in both seasons ( Supplementary Table S3 ).
A highly significant positive correlation of first two principal axes ( f1 and f2 ) with U% ( f1 = 0.411, f2 = 0.187; p < 0.0001), and negative correlation with A%( f1 = -0.149, f2 = -0.168; p < 0.0001) and C% ( f1 = -0.379, f2 = -0.111; p < 0.0001), indicates that compositional constraints (especially U and C nucleotides) affected the codon usage bias of the SARS-CoV-2 genome (Table S3).
This difference is highly significant in 4-week-old pups ( p < 0.0001) and still maintained when pups are 10 weeks of age ( p = 0.0014).
The combination of PZQ and ARA resulted in a highly significant ( P < 0.0001) increase in cure rates (78%) compared with 20% for PZQ alone but not egg reduction rates ( Table 1 ).
The established quadratic model was highly significant, as indicated by ANOVA ( Table 4 ) with a p-value < 0.0001 and an F-value of 52.17.
PERMANOVA confirmed that the difference in microbial community composition was highly significant ( P = .0001) between samples from intestine and culture water, based on both Bray–Curtis and Dice-Sørensen similarities.
The univariate analysis of factors associated with SFV infection showed a highly significant association with male sex (p<10 −4 , χ 2 = 24.6), with the Pygmies (p<10 −4 , χ 2 = 20.85), hunting (p<10 −4 , χ 2 = 233.5), apes (p<10 −4 , χ 2 = 446.2), bites (p<10 −4 , χ 2 = 267.1) and wounds to the upper part of the body.
( 47 ) revealed that associations between age and comorbidity were highly significant (p < 0.0001), as the age-adjusted risk of comorbid death was 5.7 times greater in men with severe compared to those without comorbidities.
The differences in UMH between GMA and controls were highly significant when comparing both groups under unrestricted diet or hypoallergenic diet (each p < 0.0001).
General impairment in episodic memory in post-traumatic stress disorder The overall analysis, including all memory tests and control groups from all 47 studies, shows a highly significant lower episodic memory performance in the PTSD group compared to controls ( d * = −0.50, p < 0.0001), which confirms our first hypothesis.
The model was highly significant ( F = 153.81, p < 0.0001) with a non-significant lack-of-fit ( p = 0.7526), indicating adequate fit.
The results showed that there was a statistically highly significant difference among isolates in the percentage of mean germination (F=54.6; DF=14; P<0.0001).
Again, these large differences among periods were highly significant (Kruskal-Wallis P <0.0001).
Additionally, the relation between serum IgG SRID and serum TP Refractometry was highly significant ( p < 0.0001, R 2 = 0.82).
More importantly, one-way ANOVA testing revealed a highly significant effect of flow rate on steady-state current ( F = 412.6, p < 0.0001), indicating that the current amplification observed between 0.1 and 10 μL min −1 is statistically robust.
In the subgroup, we still observed a highly significant ( P < 10 −4 ) increase in lactate of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{upgreek} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} }{}$0.0108\ \frac{\mathrm{mmol}/\mathrm{L}}{\Delta{\mathrm{S}}_{\mathrm{a}}{\mathrm{O}}_2}$\end{document} and a significant difference compared with exposure to CO ( P = 0.010).
At the end of IFN-α therapy, 36 patients (47.4%) in 3-MU group and 103 (83.1%) had ETVR, the difference being highly significant (P < 0.0001).
Meanwhile, statistical analyses revealed a nonsignificant value of the lack of fit ( p > 0.05), and a highly significant level of the model ( p < 0.0001), implying that the mode could be accurately predicted by variation [ 61 ].