All three factors: cell line, construct type and H 2 0 2 concentration, had highly significant effects (p < 0.0001) on log(RLU) after adjusting for the interactions and experiments.
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Across all 4 genes, results were highly significant ( t df = 141 = −5.72, P < 0.0001), suggesting that EGC was indeed selected against around those amino acids.
This correlation was highly significant ( p < 0.0001, χ 2 test comparing neurons with versus those without deep dendrites).
A highly significant and sustained 3–fold increase in p-AVP was measured during treatment with tolvaptan compared to placebo (Placebo: 0.20 ± 0.15 vs. 0.70 ± 0.45 pg/ml, p <0.0001).
More importantly, we found a highly significant effect of the workload manipulation on HR [ F (1, 18) = 36.1431, p < 0.0001, η 2 p = 0.667], with a higher HR for the more challenging 2-back task (mean = 80.4 ± 9.89) compared with the relatively easy 0-back task (mean = 77.27 ± 10.19).
There was a highly significant relationship between larval mortality ( p < 0.0001) and the total percentage of pupae formed ( p < 0.0001) both among concentrations and among different samples of Au-doped ZnO.
The explanatory variable “reproductive strategy” was also highly significant (PERMANOVA: p = .0001, df = 1, R 2 = .23, F = 48.37), revealing differences between pelvic and transfer brooding individuals (Figure 2 and Table S4 ).
In particular, the difference was highly significant in the case of ALS (controls: 9098.68 ± 1210.76 pg/mL; ALS: 17,235.3 ± 1033.2; p < 0.0001), and AD (18,496.00 ± 1165.27; p < 0.001) and less in the case of ID (16,180.35 ± 1323.65; p = 0.004).
As expected, highly significant differences were observed between patients and controls in global cognitive status based on the PD-CRS [t(65) = 6.5; p < 0.0001], motor symptom severity based on the UHDRS-TMS [t(65) = 10.9; p < 0.0001], functional status based on the TFC [t(65) = 7.2; p < 0.0001], as well as on NfL plasma levels [t(65) = 10.73; p < 0.0001], all with large effect sizes (d > 0.8). 3.1 Verbal episodic memory performance The three-way mixed-effects ANOVA with recall type (free vs. cued) and time (immediate vs. delayed) as within-subjects factors, and group (HD vs.
59 Bostanci et al found a significant improvement in both the psychosocial and physical measures postoperatively and highly significant effect on the overall QoL (all p<0.0001). 54 A smaller cohort study looking more specifically at body image perception found a significant improvement postoperatively. 55 Kim et al also observed a positive impact on patients’ QoL and found this to be evident early post-operatively and persistent lo
By this criterion, the fraction of cells exhibiting λ R /RAD51 colocalizations is not significantly different from background, while the fraction of cells exhibiting colocalizations of RAD51D-GFP or XRCCC2-GFP is highly significant ( P = 0.0001, χ 2 test).
As the probability (p-) column indicates, all main effects—distracter level, formant swing extent, the size of f0 separation, and assignment of the higher f0 to target or distracter—were highly significant with p = 0.0001, both within and across subjects.
(2022) found no significant differences in input resistance and spike width between Calb2 and Chrna2 cells, whereas we found highly significant differences in these parameters ( p < 0.0001 and p = 0.01, respectively, in pairwise comparisons), and also in the initial firing frequency and adaptation ratio (Extended Data Fig. 9-1 ).
SLEDAI and rSLEDAI displayed strong positive correlations, with correlation coefficients of 0.63 and 0.63, respectively, with highly significant P values ( P < 0.0001).
The likelihood of undergoing resection has been shown to decrease with increasing age, with patients of age group 65–69 years having a 71% resection rate compared with 69% for those aged 70–74 years, 62% for those aged 80–84 years, 46% for those aged 80–84 years, and 31% for those aged 85 years and older, which was highly significant ( P <0.0001) even after adjusting for confounding factors. 3 This same trend was repeated almost identically for receipt of RT within 3 months of diagnosis or receipt of chemotherapy within 3 months of diagnosis, when analyzed according to increasing age, in the same US population-based report, 3 a
There was a highly significant difference ( p < 0.0001) between the two groups: At 20 months, 65% of patients in the [ 177 Lu]Lu-DOTA-TATE group were living and free of progression, compared to only 11% in the control group [ 8 , 13 ].
This difference was highly significant using a two-tailed t-test 22 df, assuming unequal variance (P<0.0001).
The test was highly significant (QM[df = 1] = 73.32, p < 0.0001), providing strong evidence of small-study effects and/or selective reporting.
The effect of mCPP was highly significant ( F 2.24 =29.0, P = 0.0001), but there was no interaction of drug and genotype.
Insulin glargine resulted in a highly significant ( P < 0.0001) absolute reduction of mean daytime glucose level from baseline to end point: 9.9 ± 2.0 to 6.9 ± 1.5 mmol/l, which corresponds to −3.0 ± 2.1 mmol/l.
This yields a highly significant model ( p < 0.0001) and three PCs that collectively explain 94.7% of the variance (Table 2 ).
The two new functions cumulatively explained 100% of the total variance: Canonical 1 (Can1) explains 71% of the variation among the three groups with a highly significant probability ( p < 0.0001), while canonical 2 (Can2) explains the remaining 29% with a significant probability ( p < 0.005).
A highly significant ( p < 0.0001) quadratic model was developed, which exhibited an excellent fit to the experimental data ( R 2 = 0.9995).
Despite its simplicity, our model was highly significant (P<0.0001) and explained 24% of the variation in the occurrence of stop codons among introns.
The relative risk of each stage by sex (women/men) was: Stage 1 , 0.72 (more in men); Stage 2 , 1.11; Stage 3 , 1.68; and Stage 4 , 9.29 (all three more in women); these sex-differences were highly significant (overall χ 2 [d f = 3] = 51.3, p < 0.0001).