“highly significant”

For qPCR, the concordance correlation coefficients (CCC) for all pairs (A–B, A–C and B–C) exceeded 0.95, with highly significant Pearson correlations ( p < 0.0001), confirming strong concordance.

Statistical analysis revealed a positive and highly significant ( p < 0.0001) correlation between the measured germination and global 5mC levels (R 2 = 0.797), ( Figure 6 ), as well for all data that were pulled together ( Figure 5 a,b).

Models generated for different quality attributes of instant phirni dry mix were highly significant ( p ≤ 0.0001).

Unpaired t-tests comparing the seronegative and seropositive populations yielded highly significant p-values (p<0.0001) for both the Immunetics® C6 Lyme ELISATM ( Fig 2A ) and the MicroB-plex Anti-C6/Anti-pepC10 Immunoassay ( Fig 2B ).

3 , JO146 treatment resulted in complete or highly significant (p < 0.0001) loss (up to 10 3–4 log) of progeny (IFU) when added during the replicative phase.

A highly significant model (p < 0.0001) suggests its reliability.

The greater genomic parallelism within than between environments is therefore highly significant ( p < 0.0001).

3E ) mean Go waveforms ranged between 0.91 and 0.99 for the displayed sites; all were highly significant ( p < 0.0001), confirming their good approximation.

Response surface equations for peak sound pressure level (SPL peak) and effective sound pressure level (RMS) were constructed by a quadratic polynomial regression model with linear, interaction and quadratic terms, which was verified by analysis of variance (ANOVA) to be highly significant (p < 0.0001), as shown in equations (15) and (16) .

Other Clinical Efficacy Results The mean changes from baseline in the IKDC subjective score, which ranges from 0 (worst result) to 100 (best result), were highly significant at all time points (i.e., P < 0.0001; including Month 3) and increased in their extent through Month 24 (LS mean increase from baseline: 41.6 ± 1.9 points; 95% CI: 37.9-45.4).

This difference of 26 days between the older (less than or equal to 1986) and more recent (greater than or equal to 1987) FFD subsets is highly significant ( p < 0.0001).

The global F ST / R ST value at 0.34/0.64 was highly significant ( P < 0.0001), signaling a substantive genetic differentiation among the populations as a whole, and most of the pairwise comparisons displayed a pronounced level of genetic differences (> 0.25).

Highly significant difference (p < 0.0001****) of expression was observed in SSc with respect to all other groups.

Effects on Periodontal Clinical Parameters As seen in Table 2 and Figure 2 , oral hygiene instructions led to a highly significant decrease of PISA and mean BOP (%) values ( p < 0.0001) in former and non-smokers but in not in current smokers ( p = 0.94).

The correlations were weaker for the WV site, but still highly significant ( r = 0.39, p ≤ 0.0001).

A highly significant association was observed for rs1248923790 ( p < 0.0001, χ2 = 26.39). the TT genotype was significantly more common in disease cases (201) compared to controls (136), with an increased risk of disease (OR = 2.106, RR = 1.446, 95% CI: 1.249–1.679).

All three variations were highly significant for sheath blight resistance ( P < 0.0001).

The difference between the treatment groups was highly significant ( P < 0.0001).

Pooled left and right arm data were then compared between megachiropterans and microchiropterans and showed highly significant differences (T = - 8.77, P = 0.0001); and clear separation of measurements between the groups ( Fig 2C ).

The effect og age on mortality was highly significant, as only 10/538 deaths occurred below the age of 42, as opposed to 67/528 above the age of 42, p = 0.0001.

A paired t-test was applied and with considering a significance threshold of 0.05, the difference in forecasting accuracy between the models showed to be highly significant with p ≤ 0.0001 across subjects.

InsuTAG scores ranged from 0.55 to 132.07 across the whole participant group with a median (25 th –75 th percentile) InsuTAG score of 7.22 (4.04–11.33) There is a strong and highly significant positive correlation between InsuTAG and HOMA-IR (r = 0.86; p < 0.0001) (Fig. 1 ) when compared with the association between HOMA-IR and the other lipid indices, TyG index (triglycerides × glucose) (r = 0.43; p < 0.001) and TG/HDL-C ratio (r = 0.38; p < 0.001) (Table 2 ).

In contrast, inhibition of nitric oxide release by macrophages was highly significant ( P ≤ 0.0001) at higher 8A12 mAb concentrations (0.6, 1.25, 2.5, and 5 μg/mL) as shown in Figure 2 B.

Our findings uncovered a highly significant effect of MS ( p < 0.0001).

By contrast, for HCC44, the most imetelstat sensitive line, the difference was highly significant ( p < 0.0001).