“highly significant”

The primary endpoint was highly significant with an absolute EF improvement of 18.3% in the catheter ablation arm compared to 4.4% in the medical rate control arm ( P < 0.0001).

When modeling NT-proBNP−SDS dependent on height-SDS, the univariate analysis showed a highly significant negative association between NT-proBNP−SDS and height-SDS ( β = −0.08, P < 0.0001).

The interaction between ROI and model type was highly significant ( F (5,45) = 49.364, p < 0.0001).

An analysis of the z -transform of these correlations coefficients revealed that the difference was highly significant, t (75) = 8.41, p < 0.0001 (GF items with each other: z = 0.709; GF items with other items: z = 0.237).

IG# showed a highly significant difference between non-infected and infected patients early in period 1 and period 5, ( P < 0.0001).

Survival analysis revealed highly significant differences between high-risk and low-risk groups (p < 0.0001) (Fig. 5 A), with ROC curve values at multiple time points exceeding 0.7 (Fig. 5 D).

All the main and interaction effects were observed to be highly significant ( p < 0.0001).

Indeed, the genetic differentiation between the American and European continents that was detected by cpSSRs was high ( F ST = 0.369), and highly significant (P <0.0001).

While the reduced number of genes often leads to a loss of significance within each sex, the general results hold whether or not we consider the ancestral level of expression: (i) a highly significant (***P-value < 0.0001) male-biased expression of the Z, with (F:M)Z/(F:M)A ratio from 0.52 to 0.77, is always observed.

The Likelihood Ratio test was highly significant, indicating significant effect of the covariates on response (p < 0.0001).

For BPA doses, however, one-way analysis of variance (ANOVA) indicated highly significant among-group differences ( F = 7.87 ; p < 0.0001 ), and subsequent Bonferroni post hoc comparisons indicated significant differences between placebo and each exposure ( t = 3.2 , p < 0.01 for 2 ng / g ; t = 2.8 , p < 0.01 for 20 ng / g ; t = 4.0 , p < 0.0001 for 100 ng / g ; and t = 5.4 , p < 0.0001 for 500 ng / g ).

The difference between the groups was highly significant ( P < 0.0001), reinforcing LDAR as a robust prognostic biomarker for ICU mortality in septic patients with malignancies.

Here the application of CRMP-5 led to a highly significant increase in the amount of RGCs (p<0.0001).

Hence, a highly significant difference was detected between the algometric measurement before and after treatment was detected ( p <0.0001, Fig. 3 B).

The urban-rural distribution of overweight children was 189 (4.4%) in rural areas and 310 (7.6%) in urban areas and the difference was highly significant ( P <0.0001).

The cut-off value was 3.8 ng/ml, and the difference between the groups was highly significant (p< 0.0001).

Compared with the groups of healthy people, the abundance of Firmicutes showed a highly significant upward trend in the groups of UF patients ( p < 0.0001) ( Figure 2B ).

The main effects of VRN - D4 , VRN1 three homologs ( VRN - A1 , VRN - B1 and VRND1 ), and VRN - B3 were highly significant ( P < 0.0001) in all four populations.

The statistical difference between the NaCl and NaOH groups was highly significant ( p < 0.0001), confirming the non-irritating nature of NaCl.

In fact, cladistic analyses, indicating that the appendix has evolved independently at least twice (once in diprotodont marsupials and once in Euarchontoglires), show a highly significant ( P < 0.0001) phylogenetic signal in its distribution, and has been maintained in mammalian evolution for 80 millions years or longer [ 15 ].

In all cases, there were highly significant correlations (Linear regressions; whole period: r 2 = 0.292, F 1,453 = 188.1, P < 0.0001; 2015: r 2 = 0.252, F 1,157 = 54.3, P < 0.0001; 2016: r 2 = 0.377, F 1,134 = 82.6, P < 0.0001; 2017: r 2 = 0.343, F 1,158 = 84.0, P < 0.0001; SI Appendix , Fig.

There was a highly significant association for all species ( p < 0.0001) between the evaluation by CaV and SYBR/PI used as reference dye.

This performance is further strengthened by highly significant p -values (2LOmb’s global p -value < 0.0001) and the presence of common SNPs among some or all SNP pairs that are parts of three- and four-locus interactions in the 2LOmb results.

The FT-B1 alleles showed highly significant differences in heading time ( P< 0.0001) within both alleles of FT-A1 , but the differences between the adjusted means of the FT-B1 alleles were 34% larger in the lines homozygous for the mutant ft-A1 allele (25.0 day delay in flowering) than in the lines homozygous or heterozygous for the wild type FT-A1 allele (18.6 day delay).

A significant 2.5-fold decrease in cellular ATP was observed upon AA AgNP exposure ( p = 0.0040) with a highly significant elevation in mt depolarization (3.3-fold vs. control; p < 0.0001).