“highly significant”

A highly significant variation ( P < 0.0001) among the genotypes for both WSC accumulation and remobilization per GDD was found in all environments.

A highly significant correlation was observed between the individual T/N ratios of 11 C-4DST and 18 F-FLT ( r = 0.79, P = 0.0001).

The overall difference between the groups was highly significant (one-Way ANOVA, p <0.0001, F 2.31 = 57.70).

This doubling of prevalence was highly significant with a difference of 3.7% ( z = 4.10, p < 0.0001).

Notably, the genetic correlations between DB, EH, IS, OB, and HC with CKD were highly significant ( P < 0.0001), indicating that these diseases may have a stronger association with CKD due to a shared genetic basis.

The global effect of fixation was highly significant (likelihood‐ratio p<0.0001), underscoring fixation strategy as the principal determinant of postoperative FWB in this cohort.

1 )—the difference is highly significant using the Chi-square goodness of fit test ( p < 0.0001) for both the whole genome (Total) and when separating the genome into non-coding transposable elements (TE), non-coding non-transposable elements and (NTE) and exons (EX) ( Table 1A ).

One-way ANOVA revealed highly significant effects of surface type for all size groups ( p < 0.0001), with coefficients of determination ( R 2 ) of 0.958 for small, 0.976 for medium, and 0.921 for large crickets, indicating that surface texture accounted for most of the variance in the friction measurements.

This regression was highly significant (linear regression: R 2 = 0.56, F (2,2) = 34.99, P < 0.0001).

The NS1 antigen test results were highly significant with a p value < 0.0001 ( χ 2 = 253.4, d f = 3), Figure 4 .

Further, comparing the 100–300 and 300–500 ms time-windows directly using the pre-stimulus baseline demonstrates a highly significant C ondition × T ime-window × AP interaction [ F (1, 25) = 31.45, p < 0.0001].

One factor ANOVA indicates highly significant elevations in Al (p < 0.0001), Cd ( p = 0.0012), Ni ( p < 0.0001), Co ( p < 0.0001) and Mn ( p = 0.0003) as well as moderately higher Pb ( p = 0.046) and As ( p = 0.084) levels in the PE group on a bulk level.

AIA score, on the experiment termination day (day 21), showed highly significant improvement ( p < 0.0001) in TXR200 followed by DS ( p = 0.0006) and TXR100 and TXR50 groups (both p = 0.002). 3.2.3 Reduction in Footpad Thickness Upon TXR Treatment Significant reduction of mean footpad thickness in TXR-treated groups was observed in a dose-dependent manner ( Figure 3B ).

A Fisher's Z transformation on those coefficients, followed by an Olkin's Z statistic, for the TIR‐daily bolus association and the TIR‐daily scan association was highly significant ( p < 0.0001) and confirmed that the strength of association greatly favours the influence of isCGM daily scan rates over daily bolus frequencies.

The regression models were highly significant ( p < 0.0001) and accurate (lack-of-fit, p > 0.05) for all response variables ( Table S2 ), indicating good model adequacy.

Consistent with this, there was a highly significant correlation between the levels of anti-Sm near the time of biopsy and at the time of patient enrollment ( p < 0.0001) (Fig. 3 D).

Statistical analysis revealed that the differences in prevalence between the two time periods were highly significant for all three allergens: thiuram mix ( χ 2 = 1382.26, p < 0.0001), mercapto mix ( χ 2 = 179.58, p < 0.0001), and mercaptobenzothiazole ( χ 2 = 317.21, p < 0.0001). 3.2.4.

Besides, highly significant correlation coefficients were found (r = 0.80–0.93; p < 0.0001) when comparing RNA-seq and RT-qPCR results in each genotype, indicating a good consistency between the two analysis techniques and the two independent experiments ( Fig. 3B ).

On the single-cell secretion levels ( Figure 2A , 2 nd panel), the secretion rate distributions showed a highly significant difference for 1-, 12- and 24-hours of stimulation (p < 0.0001 for all) and resolved to a slight difference for the 36-hour stimulation (p = 0.04).

The difference is highly significant (p<0.0001) indicating that loss of chd-1 strongly enhances the centrosome amplification defect of the dpl-1 mutant.

The model was found to be highly significant ( p -value < 0.0001).

Gentamicin showed the most prominent change, with a highly significant shift in overall susceptibility distribution (χ2 = 95.27, p < 0.0001).

Statistical analysis revealed highly significant differences among the tested concentrations [F (6,14) = 9581, P < 0.0001].

Statistical analysis indicated highly significant differences ( p < 0.0001) between N3 and N3-O formulations, confirming that sonication significantly enhances the antimicrobial activity of Ni2CoS4 HSs across both Gram-positive and Gram-negative pathogens.

PERMANOVA confirmed a highly significant effect of time (weeks) on microbial community structure (F = 60.664; P = 0.0001), whereas treatment had no significant standalone effect (F = 0.8889; P = 0.4175; Fig. 6 ).