“highly significant”

1 ). Impact of PSE and PJ administration on the striatal DA and DOPAC levels in PQ-treated mice PQ treatment led to a highly significant reduction in the striatal DA and DOPAC levels when compared with the control mice ( P < 0.0001).

The difference between the ER values, when related to the site of metastasis, was statistically highly significant (P<0.0001) (Table III), whereas the differences between the PR values did not reach this level of statistical significance.

When the combined group of 8 patients with hypercalcaemia is compared with the control group the difference is statistically highly significant (Mann Whitney, U Test P=0.0001).

Performing a densitometry analysis of each lane using ImageJ [ 30 ], a Student’s t -test revealed a highly significant signal intensity reduction ( p ≤ 0.0001) in knockout cells (see Figure 2 D).

Quantification of the vascular density is presented ( Fig 2B ), where analysis (ANOVA) indicated a highly significant difference between the groups ( p < .0001).

Highly significant mitonuclear interaction terms were observed in each condition (ANOVA on the random effect model y ij = μ ~ mt i + n j + (mt × n) ij + ε ij , P < 0.0001, Table S 4 ) and could explain 10.8 to 31.5% of the total phenotypic variances (Fig. 1 c, Table S 5 ).

There was a highly significant difference between LAP level in compliant and non-compliant patients (1.045 ± 1.270 vs. 0.0785 ± 0.1057 ng/ml, respectively, p value < 0.0001).

There was a highly significant trend in comparing the cases with controls, such that the more risk factors that were present, the more likely was the child to develop cancer (P<0.0001).

Despite there being no significant correlation between PANSS-FSNS and SQLS-R4 baseline scores in any group, there was a highly significant correlation between the changes of these scores from baseline to week 6 that was specific to the cariprazine group in both ITT and PNS populations ( P ≤ 0.0001). 4.

There was no significant effect of bird weight (LR = 0.01, df = 1, p = 0.97) or being equipped with a GPS logger (LR = 0.13, df = 1, p = 0.67) on the proportion of time at sea, but stage of the breeding season had a highly significant effect (LR = 35.97, df = 1, p < 0.0001).

This difference was highly significant for the screen detected cancers (P <0.0001).

We found a highly significant overlap between genes that were positively correlated with USO1 across the B-ALL samples and downregulated in USO1-depleted cells (Hypergeometric test; p < 0.0001), but not in genes that were upregulated in USO1-depleted cells (non-significant p value) (Fig. 4 F, Supplementary 5C & 5D).

This difference was highly significant ( p < 0.0001) while no significant differences in sRAGE levels were found between primary and secondary APS ( Figure 4B ).

Over the full kinetic curves these differences are maintained, with differences in the P3CSK-stimulated neutrophils between low MOI Spn compared to high MOI Spn remaining highly significant ( p ≤ 0.0001; Figure 6 D).

VE/VO 2 showed a highly significant difference during the first 20 s of recovery ( p = 0.0001, r = 0.834, 95% CI: −5.05 to −3.06), whereas no significant differences were observed during the subsequent 20–40 s and 40–60 s intervals ( p > 0.05).

The correlation is highly significant with a correlation coefficient of 0.87 ( P < 0.0001, Pearson product moment correlation test).

At test re-test, Cronbach’s alpha was 0.914, while the intra class correlation was 0.9160 (95% confidence interval 0.941–0.975), which is a highly significant correlation ( p < 0.0001).

The between-subjects effect of treatment group was highly significant ( p < 0.0001 at all time points), reflecting the consistently higher amylase levels in the NNRTI/PI group compared to the INSTI group throughout the entire observation period.

The ANOVA analysis showed highly significant differences ( p < 0.0001) in the antioxidant activity between H and ZnO NP-loaded formulations, except between HZ 5 and HZ 7.5, where no significant differences were observed.

Muscle colonies formed from Bcl-2 (−/−) cells contained an average ± SE of 112.6 ± 9.7 nuclei ( n = 178), whereas muscle colonies formed from wild-type cells contained an average ± SE of 202.8 ± 11.8 nuclei ( n = 274), a highly significant ( P < 0.0001) difference.

The results showed highly significant main effects (all p < 0.0001, Supplementary Material Table S4 ) regarding nebulizer type, placement position, and artificial airway type.

This model was highly significant (F = 10.29, p < 0.0001) and BMI category ( p < 0.05) was found to be an independent predictor of SIgA concentration.

This was confirmed by a hierarchic (nested) analysis of variance (ANOVA), which showed highly significant among-cell (subgroup) variability regardless of the parameter tested (P < 0.0001, peak amplitude, risetime, halfwidth, and foot duration were tested after logarithmic transformation, cubic-root of the charge was tested without transformation).

Kaplan–Meier analysis of independent testing on two data sets ( Figure 7 ) shows a highly significant difference ( P -value of <0.0001) in terms of overall survival between the ‘early recurrence’ and ‘late recurrence’ groups.

The global correlation across all time points remained highly significant (ρ = 0.65, p < 10 −4 ).