“highly significant”

Results A highly significant difference ( p < 0.0001) was observed, indicating that miR-21 expression was higher in CML patients compared to the controls. miR-302 levels were lower in CML patients.

The M group demonstrated the smallest reduction (p< 0.05), whereas differences in the other groups were highly significant (p< 0.0001) ( Figure 8B ).

These differences were highly significant ( P < 0.0001, Figure 2C ).

Employment status was also highly significant ( p < 0.0001), with employed respondents reporting more dissatisfaction, while students tended to be more satisfied.

The results indicated that there was a highly significant association between PD-L2 and PD-L1 in these tumors ( p < 0.0001) [ 107 ].

The increase in December peak counts between 1989 and 2019 was highly significant (b = 0.129 ± 0.019; R 2 = 0.620, F 1,29 = 47.323, p < 0.0001).

Notably, there was a highly significant reduction ( p < 0.0001) at concentrations of 400 μg/ml and above, reaching maximum viability reduction after 5 min of laser irradiation (Fig. 7 A–D).

The coefficients for the two main explanatory variables (GDP per capita and occupancy rate) are highly significant (p < 0.0001), as well as most of the control dummies, e.g., hospital level.

Notably, larvae treated with 2.4 mg/mL VitB3 exhibited the most pronounced reduction in fluorescence intensity, with statistical analysis confirming a highly significant difference compared to the untreated control group (P<0.0001; Figure 1B ).

Analysis of variance revealed highly significant main effects of the modulation index levels on perceived flicker intensity [ F (3,39) = 74.13, p < 0.0001] as well as on stimulation comfort [ F (3,39) = 22.46, p < 0.0001].

The likelihood ratio test confirmed that this threshold effect was highly significant ( p < 0.0001), supporting its reliability.

Difference in scored mean marks was highly significant in term-ending-examination ( P < 0.0001, t = 5.754, df = 121.9).

In most cases, the differences were highly significant ( p < 0.0001).

As presented in Table 7 , the ANOVA results indicate that the factors of models A, B, C, D, AC, BC, BD, CD, A 2 , B 2 , and C 2 are D 2 < 0.05 (at the 95% confidence level, p < 0.05 was considered statistically significant and p < 0.0001 was considered statistically highly significant) [ 14 , 20 , 21 ], indicating that the effects of the nitric acid concentration, leaching temperature, liquid–solid ratio, total pressure, as well as the interactions between these factors and their squared effects on the vanadium leaching efficiency were significant.

However, there was a significant difference between the caudal and pectoral fins (p = 0.005), and all other pairwise comparisons were highly significant (p<0.0001).

Honey Effect The Kruskal–Wallis test revealed a highly significant effect of honey concentration on bacterial growth inhibition (χ 2 = 189.79, df = 9, p < 0.0001).

Each species also showed a highly significant ( p < 0.0001) preference for nestmate recruitment pheromone at 0.1 bee equivalents (Fig. 3 ; T. hyalinata , 80% choosing the feeder with pheromone; T. spinipes , 65%).

Correlation of ELISpot Responses to Various BK Virus and JC Virus Peptide Pools Spearman analysis indicated that, in 17 HSCT recipients with BKV-related cystitis and in 50 healthy controls, responses to the BKV LT and VP1 peptide pools showed a highly significant correlation ( r > 0.7, p < 0.0001) ( Appendix B , Table A2 ).

Multiple linear regression analysis showed, in both genders, a highly significant relationship between z-scores differences (ECSC vs GLI-2017) and age (as in the “control” group) (p < 0.0001, in both genders), the decrease in D LCO severity (p < 0.0001, in both genders) and the interaction between age and severity (p < 0.0001 in both genders).

Attending to their age we can consider two groups, one comprised by those with ages under 40 ky (R0, R5, R7 and R8) and the other with ages above 40 ky (R6, R30, R31, U, JT) with highly significant differences ( p < 0.0001) between the mean age of each group, 36.8 ± 1.59 and 53.4 ± 2.69 ky respectively.

This doubling of prevalence was highly significant with a difference of 3.7% ( z = 4.10, p < 0.0001).

This difference was highly significant ( p < 0.0001), indicating a significant enhancement in urinary function and overall quality of life in patients in the treatment group.

The random effects model indicated a significant mean difference (MD) of -1.66 (95% CI: -2.39 to -0.93), with a highly significant p-value of <0.0001, suggesting a substantial reduction in abdominal pain due to probiotic treatment.

We have also investigated the correlation between AD and early signs of age-related macular degeneration in a subset of participants of the AIBL cohort, and found a highly significant association with AD diagnosis ( p < 0.0001); the reason for this association is unclear [ 151 ] and warrants further investigation.

Consistent with this, there was a highly significant correlation between the levels of anti-Sm near the time of biopsy and at the time of patient enrollment ( p < 0.0001) (Fig. 3 D).