“highly significant”

Applying the aforementioned post hoc ANCOVA sensitivity analysis, the treatment effect defined by the primary outcome measure remained highly significant ( p < 0.0001).

Control and riboflavin-supplemented samples showed a highly significant positive correlation (r 2 = 0.99; p < 0.0001) according to the global expression correlation analysis ( Figure 5a ).

At both time points, highly significant increases in STAT6 phosphorylation (pSTAT6) (Fig. 3 b,c), as well as pSTAT3, was detected in both T cell subsets (p < 0.0001 for all) (Fig. 3 d–f).

Finally, Spearman correlation tests between the 25(OH)D concentration values and the absolute and percentage root mean square precision errors (RMSCV and RMSCV%) were performed, showing the highly significant correlation, with r = 0.44 for the absolute root mean square precision error (RMSCV; p < 0.0001) but not for the root mean square precision error expressed in percentages (RMSCV%; r = −0.14; p = 0.08). 4.

Permutational multivariate analysis of variance confirmed that compositional differences among the three associations were highly significant (F = 7.658, p = 0.0001, 9 999 permutations), a result corroborated by the rank-based test of similarity ( R = 0.6135, p = 0.0001).

Sample positivity increased with neighborhood deprivation, and this trend was highly significant across all periods considered ( p < 0.0001 across all years and for each two-year interval except for 2021–2022, which had p = 0.024; Fig. 3 ).

The differences between time points were highly significant (**** p < 0.0001), reflecting structural maturation of the biofilm ( Figure 6 ).

Across all genomes, ERs were markedly closer in GC content to their host chromosomes than to unrelated chromosomes (median matched GC difference was 3.0%, compared to 10.9% for unmatched pairs), a difference that was highly significant ( p < 1 × 10−4) and associated with a large effect size (Cliff’s δ = −0.63).

Highly significant difference were also found between the scores of four education groups (p = 0.0001).

As demonstrated in Figure 3 A and 3 B , there was a highly significant correlation between CD4 + T-cell expansion and both the maximum ( r = 0.53, P < .0001) and fold-increase in ( r = 0.46, P = .0004) microneutralization titer.

Figure 2B illustrates the comparison of true versus predicted ages, yielding a Pearson correlation coefficient r of 0.56 and a highly significant p -value ( p < 0.0001).

The interactions of Wolbachia and elevated CO 2 concentration on total protein, amino acid content, peroxidase activity, and amylase activity were highly significant (two‐way ANOVA, F = 43.979, p < 0.0001; F = 34.696, p < 0.0001; F = 22.865, p < 0.0001; and F = 22.873, p < 0.0001), resulting in increased nutrient content and enzyme activity, which may be beneficial for H. graminicola in future. 4 DISCUSSION Wolbachia , an endosymbiotic bacterium, widespread in insects and Arachnida, have important effects on growth, development, and reproduction.

The results of the present study reiterated the fact with similar findings of highly significant correlation between the BMI and NC ( r = 0.459, P < 0.0001).

However, the same 19% survival advantage observed between Stage IIIA cases and Stage IIIC cases treated at SEER institutions was highly significant ( P < 0.0001) when a greater number of patients were included in both Stage III subgroups.

Regarding in vitro drug release, the model was highly significant ( p < 0.0001), with both Factor 1 (A: Ca3(PO4)) and Factor 2 (B: Trehalose) significantly influencing the response.

2 ) shows a very good fit to the data and all models were highly significant (p<0.0001, Table 3 ).

Substance P cells showed a higher frequency of both sEPSCs and mEPSCs (6.04 ± 0.96 Hz sEPSCs, 3.24 ± 0.67 Hz mEPSCs, n = 27 and 11, respectively) than GRP cells (0.2 ± 0.05 Hz sEPSCs, 0.02 ± 0.01 Hz mEPSCs, n = 120 and 32, respectively), and these differences were both highly significant (sEPSC, Mann–Whitney, U = 68, P < 0.0001; mEPSC, Mann–Whitney, U = 0, P < 0.0001; Fig. 6 ).

The correlation of inter-electrode distance with inter-electrode PLI was very weak in all subjects at all frequency bands (median rho over frequency bands: −0.06<rho<0) with no clear direction, albeit highly significant in single subjects (maximal positive correlation: rho = 0.15, maximal negative correlation: rho = −0.19; p<0.0001) due to the high number of values (214*213/2 data points per subject).

The difference between total mortality of treated and control groups was highly significant (P= 0.0001) ( Jalilnavaz et al. 2016 ).

Total glutathione was decreased by about a factor of two in both mutants and controls exposed to galactose plus paraquat as compared with galactose alone; this difference was highly significant ( P <0.0001; Fig. 6A ).

Results (a) Comparison of the modes and magnitude of skull shape diversification in Darwin's finches and Hawaiian honeycreepers Morphometric analyses in which the more-inclusive landmark datasets were employed (using the final set of 15 landmarks which allows the extinct Hawaiian honeycreeper species to be analysed) on Darwin's finches, Hawaiian honeycreepers and their respective outgroups, reveal a highly significant degree of allometry ( p < 0.0001), which explains 12.6% of the variation in shape of the skull (electronic supplementary material, table S5).

This two- to three-fold enrichment for HGT C was highly significant (binomial GLM, estimate = 1.18, SE = 0.07, P < 0.0001; Fig. 2 ; Supplementary Table 3 ) in both species at both timepoints.

Relationship between lung neutrophil content and BUN To further examine the relationship between kidney function recovery and lung inflammation, BUN levels were correlated with lung neutrophil percentages (from all AKI experiments) and the correlation was highly significant ( P < 0.0001) with higher levels of BUN correlating with higher levels of lung neutrophils (Fig. 7 , n = 61).

sustained response types between IC ipsi and IC contra in tinnitus GPs was highly significant [χ 2 (1) = 46.42, P < 0.0001].

From this functional enrichment analysis, annotation levels 1 through 3 were derived and summarized in a specific key annotation term for 170 modules ( Table S5 ), i.e., when annotation terms were highly significant ( p < 0.0001) and show a similar theme or could be linked to the enriched TF, which was included in further analyses (see following text).