However, 49 cases of co-infection were observed and 10 cases of infection with only Paramarteilia , a result that is highly significant (Chi-Square; χ 2 = 39.4, df = 1 P < 0.0001) and consistent with that found in a previous survey 13 .
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The observed alterations regarding the differences in circumference were highly significant, showing an increase of 77% for actin and 75% for cofilin ( p < 0.0001).
This bias toward below-mid-parent heterosis was highly significant (binomial test P < 0.0001).
Obtaining a tumor-free surgical margin decreases the incidence of a local recurrence (LR) of the primary tumor.[ 18 ] There are various risk factors associated with a positive margin, among them are: The extent of excision, age, large tumor size, multifocality, lobular histological type, and the number of positive lymph nodes.[ 19 ] In 30 of 34 reviewed studies, persistent microscopic inadequate (R1) or macroscopic inadequate (R2) surgical margins were highly significant for LR compared to the negative margin (p = 0.0001).[ 20 ] Microscopic disease resulting from a positive margin is more problematic because theoretically, cancer in the relatively hypoxic environment of the lumpectomy scar bed will be resistant to radiation therapy.[ 21 ] Furthermore, the inability to achieve negative margins may be a marker of an excessive tumor burden in the treated breast.
By contrast, in 0.3 pmol MO zatxn7 SPL morphants, we observed a highly significant decrease in the number of Purkinje cells at 5 (90+/−18, n = 5, p <0.0001), 6 (104+/−25, n = 6, p <0.0001), and 7 dpf (143+/−23, n = 6, p <0.0001) ( Figure 6D–6F ), strongly suggesting that partial zebrafish atxn7 depletion partly compromised, but did not slow down Purkinje cell differentiation.
There was a highly significant difference between the sizes of eggs of female 1 (1.000 ± 0.083 mg) and female 3 (t = -3.84; p = 0.0001).
However, there was a highly significant ( p < 0.0001; d = 2.41) performance difference in favor of the VP group which doubled its test scores with 60.8 points (SD = 9.6) and showed a stronger effect size (d VP = 3.3 vs. d SGT = 1.42) than the SGT group which achieved 40.3 points (SD = 7.2).
Meta-analysis with a one-stage random effects Cox regression model confirmed a highly significant reduction in the risk of death for patients receiving chemotherapy and SC compared with SC alone (HR=0.63, 95% CI=0.51–0.77, P <0.0001, Figure 1 ).
The preference for reachable locations was highly significant ( χ 2 test, two nearest LEDs against the three farthest ones, P<0.0001).
However, the combination of drought and deforestation dried out almost all transplanted bromeliads (WV = 0 mL in each bromeliad, except for one plant subjected to simultaneous disturbances), so there was highly significant difference in pairwise comparisons testing combined disturbances vs control or vs drought alone in the forest ( p < 0.0001 for all).
The Bartlett's test on the control distribution showed that this variability was highly significant ( p < 0.0001, χ 2 = 409.19452).
The exponential increase in rDio3os expression between E and C groups together and separately by developmental stage is highly significant by Chi-square analysis ( p > 0.0001) although the absolute differences in mRNA expression levels between groups are not significant by two-way ANOVA.
Seventy-four samples were run in parallel using both methods, and there was a highly significant correlation between the two measurements (r = 0.97, p <0.0001).
The chi-squared test for heterogeneity of studies was highly significant ( P < 0.0001) suggesting that the reported HRs of the individual trials are substantially different.
A highly significant correlation between 24-h protein intake and 24-h urine urea excretion was found (t 50 = 15.7, p<0.0001) ( Figure S2 ).
Spearman’s rank correlation identified a highly significant (p ≤ 10 -4 ) positive correlation between methylation values determined by the Illumina Infinium platform and those defined by qMSP, for all of the 4 genes under analysis ( WNT10B , TUB , ALOX12B , SLC6A11 ; Figure 4 ).
A significant decrease was found for the 4 Gy (p<0.001) and 8 Gy (p<0.05) irradiation groups at 4 h post-irradiation ( Figure 2C ), and highly significant changes across the dose range of 2–8 Gy (p<0.0001) were found at 24 h post-irradiation ( Figure 2D ).
Regarding age groups, the prevalence of infection was highly significant (p < 0.0001).
The F -values were highly significant at p < 0.0001 for all response variables, and the p -values were a coefficient significance check, together with the operating factor's power.
This effect is highly significant ( p < 0.0001).
The difference was highly significant ( p < 0.0001).
Due to the lack of any significant effect of fructose feeding, data were pooled ( n = 10) and analysed by Spearman’s correlation analysis (data not shown), which revealed a highly significant within-subject correlation between intestinal and hepatic fractional DNL values in both the fasted (ρ = 0.939, p < 0.0001) and postprandial states (ρ = 0.818, p = 0.004), indicating a strong association between these two parameters. 3.4.
The students with JIA who were able to attend school were absent much more often than controls (63% compared to 20%), with a highly significant p value (p<0.0001).
Overlapping transcripts between MCDD mice and HCC did show a weak and highly significant agreement in direction of transcriptional change (R 2 0.085, P < 0.0001, Figure 6I ).
The difference in the surface area was highly significant ( P < 0.0001).