Otherwise, our shuffled genes would not show the highly significant statistical association in amino-acid divergence K a we observe between sequence domain pairs (Figure 5 ; Pearson's r 0.47, Spearman's s 0.45, P < 0.0001 for both).
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Western blotting further revealed decreased ARR3 immunoreactivity in the MUT group (Figure 3 F), with highly significant differences between groups ( p < 0.0001).
We also found highly significant differences in CD8, CD4 and CD3 staining in tumors between TIL growers and non-growers (p<0.0001).
The effect of FD on the frequency of novel phenotypes remained highly significant ( P < 0.0001) even when fitted after the presence/absence of each single genotype, indicating that the observed patterns were not due to a sampling effect (that is, the inclusion of a particular genotype in the community) ( 15 ).
Biochemical analysis has showed that ALB was highly significant in HCC than control group (P =0.0001).
Nevertheless, the density of Matrin3 tags around repressed compared to control exons was highly significant ( P < 0.0001, χ 2 test).
The mixed-effects model analysis indicates highly significant effects of time, treatment groups, and their interaction on hepatocyte viability ( p < 0.0001 for all).
The three way interaction of task performance, BrainAGE, and APOE variant proved highly significant as already derived from the analysis with the IFX toolbox ( b = 0.70, SE = 0.11, t = 6.19, p < 0.0001).
As expected, the correlation between SNPP value of hybrid F 1 and the total GCA effect of parents was highly significant ( r = 0.82; P < 0.0001).
The resulting variance model performed was highly significant: F(15,318) = 14.8742, p < 0.0001, both for the individual explanatory variables and their respective crosses.
Significant increment was shown at 8.5 minutes of exercise in volunteers and patients in group A, but not in group C. Change-in-angle scores There was a highly significant effect of exercise stage on the change-in-angle scores (p-value < 0.0001) adjusting for groups; mean change in angle scores at 2.5 min, 5.5 min and 8.5 min were 44.9, 63.8 and 79.0, respectively.
When serum retinol δ 13 C was analyzed with 3-factor ANOVA, all main effects, the VA × carrot interaction, and the maize × carrot interaction were highly significant (all P ≤ 0.0001).
As shown in Figure 4 , the diagnostic power of C6Ma1 and C6Ma3 was highly significant with an AUROC of 0.90 ( P < .0001) and of 0.87 ( P < .0001), respectively when comparing healthy control to patients with cancer.
Regional comparison (Paired t-test) In contrast, a highly significant difference was observed between the maxillary and mandibular vertical components within the same specimens ( p < 0.0001).
The one-way ANOVA results confirmed highly significant differences ( p < 0.0001) across the median normalized log2 signal intensities in all five examined subcellular fractions, with the strongest effects observed in the endoplasmic reticulum ( p = 5.6 × 10−14, F = 1134) and mitochondria ( p = 1.8 × 10−12, F = 599), where the addition of DDM substantially increased signal intensity.
AUC analysis revealed a highly significant difference ( p < 0.0001) between untreated infected animals and all treatment groups.
When treated with EAE-AS, the comparison of Caspase 3 expression between neurospheres and N2a is highly significant ( p < 0.0001).
When asked about their education level, summarised in Figure 4 , data showed a highly significant difference between the countries ( p < 0.0001). 3.2.
The log-rank (Mantel-Cox) test revealed highly significant differences between survival curves (χ2 = 86.49, df = 4, p < 0.0001), indicating that survival probability strongly depended on age at the time of infection.
Splenocytes from mice vaccinated intravenously with RALA/ mGPC2 produced highly significant levels of antigen-specific IFN-γ (107.1 SFU/250,000 cells ±18.65; p < 0.0001) and IL-2 (100.6 SFU/250,000 cells ±22.61; p < 0.001).
In the first group, there were highly significant differences in the pre and post intervention measures of WOMAC of pain, stiffness, physical function, and total score: p=0.0001 for pain, p=0.0001 for stiffness, p=0.0001 for physical function, and p=0.0001 for the total score.
Barlett’s Test of Sphericity was highly significant ( c 2 = 1,106, df = 190; P < 0.0001) suggesting sufficient correlation between variables.
A highly significant and sustained 3–fold increase in p-AVP was measured during treatment with tolvaptan compared to placebo (Placebo: 0.20 ± 0.15 vs. 0.70 ± 0.45 pg/ml, p <0.0001).
There was highly significant difference (p <0.0001) in body mass index between controls (21.61±3.52 Kg/m2) and PTB patients (17.47±1.56 Kg/m2) [ Table 2 ].
The multiple regression model was highly significant [ F ( F (2, 114) = 117.9, p < 0.0001] and the R squared was equal to 0.67.