“highly significant”

In the control group, the range was 6–11 mm with a mean of 8.375 mm ( Table 1 ) and the difference between the control and the patient groups was statistically highly significant ( p < 0.0001).

These results indicate that the antibacterial effectiveness of SH and BF is preserved throughout the extraction process and their transformation into nanoparticles, with statistical analysis confirming highly significant differences in antimicrobial activity between sample types for both ( F (5,12) = 252.15, p < 0.0001) and ( F (5,12) = 108.81, p < 0.0001).

5a, b ) revealed a highly significant depletion of the presynaptic marker synaptophysin (normalised to the neuronal marker Tuj1) in TgCRND8 cultures when compared to WT ( p < 0.0001) (Fig. 5c ) that appears to worsen with the age of the slice ( p = 0.054).

The log-likelihood ratio tests indicated that both group and kin effects were highly significant (p < 0.0001).

This was highly significant but represented only 0.55% of explained variance ( χ 2 ( df = 1, n = 4723) = 25.60, p < 0.0001, φ = 0.074).

Stake size’s effect on cooperation rate in each role was highly significant in the first three roles (generalized linear mixed model analysis: simultaneous role, F (2, 1434) = 82.90, P < 0.0001; first player role, F (2, 1434) = 76.88, P < 0.0001; second player role in which the first player cooperated, F (2, 1434) = 32.04, P < 0.0001).

For instance, decreasing the incubation temperature from 37 to 30°C or room temperature, had a highly significant effect on the total aerobic count for samples collected from the low care zone ( p < 0.0001).

Interestingly, the overall number of negative predictors was lower (median 2.0, range 0–5) in individuals with SVR versus patients with virologic failure (median 3.0, range 1–5) and this was highly significant ( Fig 4A , P <0.0001).

In contrast, tg a 20 +/+;TK+ mice treated with GCV showed a median incubation time of 50 dpi, with a highly significant acceleration of progression compared with PBS-treated tg a 20 +/+;TK+ mice (7 d; P < 0.0001; Fig. 2 A ); under no other conditions were tg a 20 mice reported to develop scrapie so rapidly.

In comparison, the well-developed t-tubule network staining of ventricular myocytes occupied 6.945±0.395% of the cell cytoplasm ( Fig 4Aii ) ( n = 24) which was highly significant (P<0.0001).

Correlation of serum miR 21 to age; tumor size and biochemical and molecular investigations revealed that miR 21 was directly correlated to α-fetoprotein (P = 0.006, significant); HDL (p < 0.0001, highly significant); miR -199 was inversely correlated to α-fetoprotein (P = 0.009, significant); miRNA 155 as directly correlated to α-fetoprotein (p = 0.001, significant) and serum total bilirubin (p = 0.037, significant).

The administration of metformin, acarbose, and a combination of the two drugs for 6 weeks revealed a highly significant decrease in the FBG compared to the untreated diabetic rats (P = 0.0001).

There was a highly significant decrease in subcutaneous abdominal adipocyte size with four to five weeks of 60 % CER of 4066 μm 2 to 3593 μm 2 (–11 %; p < 0.0001), which occurred in association with an 11 % reduction in total body fat.

We used the adonis2 function in the qiime2 plugin (q2-diversity) to perform permutational multivariate analysis of variance (PERMANOVA) with 999 permutations, and the included interaction terms (see Table S3 in the supplemental material) and separation of the groups were highly significant ( P = 0.0001).

Using model estimation of the change in diversity indices associated with 3 months of age we found that the increase in diversity was highly significant for all children as well as those in the case and control groups separately for all diversity indices examined (P <0.0001).

We found highly significant evidence that polytrauma patients have more than twice as many days off work (representing an increase of 120 % of the average days of work absence; p < 0.0001) compared with non-polytrauma patients.

1a , the AKI peptide marker model enabled prediction of AKI with an AUC value of 0.81 and a range within the 95 % confidence interval (CI) from 0.72 to 0.88, which is highly significant ( p < 0.0001).

The antagonistic strains had a highly significant effect on fungal growth ( F -value = 26333.5, p < 0.0001) ( Figures 2 , 3 ).

In VPAC2 wildtype (+/+) mice, PK2 mRNA demonstrated a highly significant diurnal expression with calculated peak ZT 5:10 (p-value<0.0001) ( Figure 7 ).

Analysis assessing model fit revealed a better fit for the model including CASP-12 score, depressive symptoms, age and sex (Bayes information criterion 42,354.75) compared with the same model excluding CASP-12 score (Bayes information criterion 42,402.88) (a lower Bayes information criterion score indicates a better model fit); this difference was highly significant ( p < 0.0001).

A highly significant correlation (r = 0.74, p < 0.0001) between the LAST and the short version of the Token Test indicated good external validity of the scale.

The reduction in Wexner score after 8 weeks of treatment when compared with baseline was highly significant for all NRL001 treatment arms ( p < 0.0001) as well as placebo.

The means and standard errors of RDS of Hitomebore and Kele by cut-panicle inoculation were 82.4 ± 15.4% and 30.6 ± 4.4%, respectively, and the difference was highly significant ( P < 0.0001).

Population analysis Linkage disequilibrium tests performed on the whole sample were highly significant ( I A S : 0.0703; P <10 −4 ) and the pairwise variance (V D : 4.3845) was greater than the 95% critical value ( L : 2.6948).

Table 2 shows that there was a highly significant difference in the mean of P300 latency between mild and severe ( P < 0.0001), mild and very severe ( P < 0.0003), moderate and severe ( P < 0.0001), moderate and very severe ( P < 0.001), and between severe and very severe ( P < 0.01) level of depression.