The impact of each factor on the model is considered highly significant ( p ≤ 0.0001), and according to the F-values, the order of the influence of extraction conditions on LRM-ELN yield is as follows: A (concentration of PEG6000) > B (relative centrifugal force) > C (incubation time), indicating that the concentration of PEG6000 is the key factor affecting the yield.
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A highly significant QTL (p < 0.0001) was detected on chromosome Z between microsatellite markers MCW258 and MCW241 (at 21.40 Mb and 34.26 Mb, respectively) [see Additional file 1 ].The effect of this locus was 15.28 HU.
A mixed model for repeated measures was used to determine predictors of LVMi change over time and was found to be highly significant overall in predicting LVMi change (p<0.0001).
The obtained mathematical model of TI was highly significant ( p -value < 0.0001).
A linear regression model fitted with HbA1c reduction as the outcome and baseline HbA1C as the predictor demonstrated a highly significant relationship R 2 =0.74; p<0.0001 ( figure 4 and online supplemental file 6 ).
Highly significant increases of DMG were observed upon intake of both Superba Boost TM ( p < 0.0001) and choline bitartrate ( p < 0.0001), while this was not the case for fish oil ( p = 0.1091), as shown in Figure 4 .
There was a highly significant correlation between the amount of BECN1 and PIK3C3 ( Fig. 7D , R = 0.86, p<0.0001) in agreement with their combined role in forming the autophagy inducing PI3K complex.
All three factors had highly significant effects ( p < 0.0001), and signal intensity levels were compared between the species using Student’s t -test on residuals after the effects of Dye and Subarray had been removed.
This upregulation was statistically highly significant ( p < 0.0001) ( Figure 3 ).
The increases from month 4 to month 12 were highly significant for each group (p = 0.0001).
The results demonstrated highly significant differences (p < 0.0001) in a log-rank test.
Kaplan-Meier analysis was not possible in the 74 week group since no z_Q175 homozygous animals acquired the response within the available timeframe (also note the small n in this cohort) but analysis of the 53 week animals confirmed that there were highly significant differences amongst the groups, Logrank (Mantel-Cox) χ 2( 2 ) = 32.8, p < 0.0001 .
A two-sample t test showed a highly significant difference between the 10 Little Dolphins children with CIs and the 44 children with CIs from the two previous studies ( t = 5.812, p < .0001).
Findings A highly significant correlation between Hounsfield units and trabecular bone mineral density was detected ( r = 0.93; P < 0.0001), and local bone density was significantly increased in the anterior and posterior area ( P = 0.0003).
2B ), and this difference was highly significant ( P < 0.0001; unpaired t -test).
The mean body weight of the intervention group at baseline was 55.75 ± 8.61 kg, which was reduced to 54.28 ± 8.12 kg at the end of the study; this difference is highly significant ( P = 0.0001).
Comparison of gene expression levels obtained from RNA-seq and qRT-PCR showed a highly significant Pearson correlation coefficient (r) (M1: r = 0.9509, P < 0.0001; M2: r = 0.9242, P = 0.0004; Fig. 3d ).
Results Variation in Cocoa Butter Fat Levels and FA Composition Extensive variation was found in the progeny of the MP01 population: The effect of genotype was highly significant in the MANOVA ( p < 0.0001) with Wilk’s λ = 0.01 and in the univariate case and was found to be significant in all the FAs and percentage of fat content ( Table 1 ).
At month 12, this finding was even highly significant for HLA class II ( p < 0.0001).
Results The Dutch breeding bird fauna, as well as all habitat communities underwent highly significant directional change ( p <0.0001) between 1984 and 2009 ( Figure 2 ).
Fig 2b supports this hypothesis: ANOVA tests confirm a highly significant effect for those who received help ( F = 26.89 and P <0.0001 – an increase of two times more shared onions per soup delivered) compared to those who did not receive help ( F = 0.61 and P = 0.44).
We found a highly significant relationship to IgM RF ( r = 0.45, P < 0.0001) (Figure 1 B), with a much weaker relationship to IgG ACPA ( r = 0.17, P = 0.03) (Figure 1 D).
Linear regression modeling Linear modeling confirmed the highly significant relationship between PTH and vitamin D status (according to 25(OH)D; P < 0.0001; Table 2 ).
Both fungal strains (S2 and S3) caused a highly significant mortality to the ants when applied at high doses in the challenge ( Fig. 1 and Table 1 ; C-C vs C-S2, early challenge: d.f. = 3.9, P <0.0001, late challenge: d.f. = 3.3, P <0.001; C-C vs C-S3, early challenge: d.f. = 5.1, P <0.00001, late challenge: d.f. = 4.1, P <0.0001).
We therefore performed one-way MANOVAs which showed highly significant differences among vegetation types within the tropics ( F 2,67 = 27.33, P < 0.0001) and the temperate zone ( F 2,55 = 6.54, P = 0.003), and in the combined analysis ( F 5,122 = 14.5, P < 0.0001).