“highly significant”

Statistical analysis revealed highly significant differences among the tested concentrations [F (6,14) = 9581, P < 0.0001].

Statistical analysis showed a highly significant correlation between pVNT and VNT titres (Spearman’s rank correlation r = 0.86; p < 0.0001).

For these patients with detectable cell proliferation, inhibitor treatment resulted in a highly significant antiproliferative effect compared to untreated controls ( p ≤ 0.0001, Kruskal Wallis test, Dunn ́s post-hoc test), for all inhibitors except lonidamine and AZD3965.

Additionally, post hoc Tukey’s test showed a highly significant effect of all 2-DPMP concentrations in both CPu ( ++++ P < 0.0001) and NAc shell ( **** P < 0.0001) against control values where no drug was present.

By 8-week intervention end, there was a highly significant decrease in the in the emotional exhaustion ( P < .0001) and depersonalization score ( P < .0001), with highly significant increase in the personal accomplishment ( P < .0001) MBI subscales as compared to baseline.

Chi-square test for trend was highly significant ( p < 0.0001).

In the Kruskal–Wallis analysis, the Ma QTL was supported with a highly significant (P < 0.0001) value of the K statistic, 15.9 for malic acid content.

The greater genomic parallelism within than between environments is therefore highly significant ( p < 0.0001).

When such analysis was performed on the gene expression profiles indicative of multifactorial gill disease, IPA identified 15 top upstream regulators associated with 101 of the 235 submitted DEGs, all highly significant (overlap P -value < 0.0001) and activated ( z -score > 2) ( Figure 7 and Supplementary Table 9 ).

HDL-C Patients that died had a highly significant lower serum HDL-C on day 1 of ICU admission (p < 0.0001, meta-analysis t-distribution) with a pooled mean difference of −7.06 mg/dL (95% CI −9.21 to −4.91 mg/dL) across 17 studies with 1542 participants 17 , 20 , 22 , 31 , 32 , 34 , 36 , 37 , 40 , 41 , 43 , 45 , 46 , 47 , 48 , 50 , 51 ( Fig. 3 ).

Glycated hemoglobin was highly correlated with UAE ( r 2 = 0.6166, p < 0.0001; Figure 3B ), whereas the correlation was comparatively weaker for kidney/body weight ratio, though still highly significant ( r 2 = 0.4280; p < 0.0001; Figure 3C ).

Both single and average intra-class correlations of each country were highly significant ( p < 0.0001), but the averaged seasonal data demonstrated higher reliabilities than individual data, as seen from larger correlation coefficients (Table 3 ).

Pairwise F ST among the five apricot clusters were all highly significant ( P < 0.0001; Table 4 ).

Quantitation of the dispersal of the TGN in SS-RARP2 transfected cells confirmed that the TGN disruption was highly significant (p < .0001) when compared to cells transfected with Iowa-RARP2-GFP, SS-RARP2-C109A-GFP, or EGFP ( S6B Fig ).

This correlation appears modest, but it is highly significant (at p < 0.0001), especially between 1<RPKM FP <1024, indicating that RPKM FP can be a good proxy of protein-production by canonical ORF translation at moderate to high levels.

This confirms the ANOVA test, where the two interaction factors (AB) were found to be highly significant (P < 0.0001).

A highly significant reduction in the expression levels of the target genes, with a p -value of < 0.0001 compared to the control, was detected for both tested isolates C6 and C21.

Interestingly, a highly significant difference in sensitivity to microtubule destabilising agents vincristine ( P < 0.0001) and vinblastine ( P < 0.0001) was seen between pre-treatment BTOR4.1 and both post-treatment lines BTOR4.2 and UBTOR4.2.

This difference in syllable count was highly significant (paired t-test: t = 11.6, P <0.0001, df = 22).

After excluding asystole patients with presumed CO = 0 L/min, the association between PetCO 2 and CO remained highly significant ( P < 0.0001).

This reduction in restriction proved highly significant in the other two groups, were we observed a 2.24 and 2.49 fold increase in the AHI-156 and CHI group compared to CG respectively (both p < 0.0001) ( Fig. 3 C).

These reductions were highly significant (ANOVA, F = 55.9, P < 0.0001) and 90% of mosquitoes died within 20 minutes of exposure (Figure 2 ).

Depression symptoms The analysis of data using the Mann–Whitney U -test revealed that after 12 months of active treatment, the general level of depression symptoms significantly decreased from 21 to 14 ( Table 2 ) (median decrease 3, P < 0.0001) among Polish patients and showed a highly significant reduction from 22 to 12 (median decrease 7, P < 0.0001) in the Germany patients.

3E ) mean Go waveforms ranged between 0.91 and 0.99 for the displayed sites; all were highly significant ( p < 0.0001), confirming their good approximation.

Our data suggest a highly significant association of MAS with PH in IUGR neonates ( p = 0.0001 ) but BA, RDS, gender, GA (weeks) and WP as a non-significant risk of PH.