“highly significant”

In all three studies, the primary endpoint was achieved, with a highly significant reduction in PANSS total score from baseline to endpoint (p < 0.0001).

ANOVA RM showed there was no effect of Day ( F (4, 20) = 0.248, p = 0.908) or Day*Trial interaction ( F (12, 60) = 0.788, p = 0.661), but a highly significant main effect of Trial ( F (3, 15) = 17.73, p < 0.0001), upon the slope.

The mixed effects model confirmed that location was a highly significant predictor of nesting (z = -7.942, P < 0.0001), whereas probe type was not (z = 1.205, P > 0.05) for the three probe types deployed at all locations (A330, 737–800, 747–400): however, when all probes are considered across all locations, 86% of blockages occurred in probes with a diameter range of 5–8 mm.

Adhesion Protocol Comparisons In comparisons of different adhesion protocol groups for each RBC, there were highly significant differences between and among groups for all RBCs: FOBF ( F =266.87, P <0.0001), TNCBF ( F =173.16, P <0.0001), and Z350XT ( F =103.64, P <0.0001).

However, hypomimia and speech impairment from V0 to V24M in males but not in females was highly significant ( p < 0.0001) ( Table 4 ).

Firstly, using geographic origin as a trait, a highly significant association was found ( AI = 8.8954, P < 0.0001; PS = 69.3392, P < 0.0001) ( Table 2 ).

In the Scottish population, we demonstrate a highly significant association in IBD ( p < 0.0001) and UC ( p < 0.0001), and an association with CD of borderline significance ( p = 0.03).

These effects were highly significant when compiled across multiple experiments ( Fig. 3 C ) ( P < 0.0001).

Marker-trait associations of early vigor in wheat landraces For the water deficit condition, 54 highly significant marker-trait associations (MTAs) were identified across all chromosomes with the FarmCPU method at a significance level of –log 10 P- value >4 ( Table 2 ).

According to Mann-Whitney-U-test this difference is highly significant with p < 0.0001.

However, a highly significant and strong correlation ( p < 0.0001) was found between the number of nuclei per OC and the percent eroded surface per bone surface in vitro ( Figure 4 b).

R6/2-PBS mice was highly significant ( p < 0.0001) ( Figure 4 A,B).

Analyses of tumour characteristics by year of diagnosis showed a significant trend towards lower risk tumours in more recent years, driven by a highly significant trend towards lower nodal status (p<0·0001 for both oestrogen receptor-positive and oestrogen receptor-negative groups; table 1 ; appendix p 35 ).

These analyses collectively illustrate a clear separation between the two intensity conditions, despite considerable distributional overlap, highlighting the robust influence of stimulus intensity on the ratings. Turning to the stimulus duration factor, it had a highly significant main effect on duration ratings, F (1, 728) = 199.45, p <.0001, η p 2 = 0.17 (Table 4 ), also confirming the hypothesis.

The high chi-square value indicating a highly significant association (p < 0.0001) between the two variables.

The model was found to be highly significant ( p -value < 0.0001).

In the HKT group, the following improvements were observed: PH domain: p = 0.0006 (highly significant, Figure 10 ); Pain domain: p < 0.0001 (extremely significant, Figure 11 ); FA domain: p = 0.0428 ( Figure 12 ).

A main effect of Emotional Expression was highly significant ( F (5,245) = 78.15, p < 0.0001; effect size, η 2 = 0.615).

The model F-value of 178.56 indicated that the model was highly significant at p < 0.0001.

The degree of shift to higher persistence of the multistate clusters compared to single-state appears roughly similar for all four pathogens and is highly significant (all P -values < 10 −4 , Mann–Whitney U test).

Highly significant decrease in the VAS score and mean lesion size score was noted over the periods of follow up at 1, 2, 4 weeks and 2 months (p = 0.0001) when compared to topical corticosteroids.

In the seated position, a moderately strong positive correlation was observed (r 2 = 0.34), which was highly significant ( p < 0.0001) ( Figure 3 ).

Allelic association tests yielded 93 highly significant SNPs (p < 10 -4 , corrected for permutation tests).

The statistical analysis using ANOVA test with equal sample size across groups ( n = 10) revealed a highly significant difference among the different current levels ( p < 0.0001), indicating that the response was strongly dependent on the magnitude of the applied current.

No significant difference existed between the caecal loads of the Δ pegA :: cat and Δ pegA mutants ( P values 0.27 and 0.64 at 1 and 3 days post-inoculation, respectively); however in both cases a highly significant reduction in caecal load was detected for each mutant relative to the parent strain ( P values < 0.0001 at 1 day post-infection), consistent with previous findings.