“highly significant”

There was a highly significant repeated measure effect of time bins, suggesting changes in freezing as the testing session progressed (F(5,12)=105.05, p<0.0001), but no between group difference (F(1,16=0.61, ns) nor interaction effects (F(5,12)=0.97, ns).

The Top ICH genes had highly significant and similar associations within the primary cluster that included intratumoral densities of CD45 + (r = 0.53–0.67, all p < 0.0001), CD8 + T cells (r = 0.48–0.71, all p < 0.0001, Fig. 3 B), CD20 + B cells (r = 0.47–0.56, all p < 0.0001), and CD138 + cells (0.37–0.5, all p < 0.0001, Additional file 1 : Table S1).

We found that in Group I (PV), the mean imaging time was 106.34 ± 19.08 s, the mean needling time was 412.36 ± 28.19 s, and hence the mean performance time was 8.64 ± 0.54 min, whereas in Group II (PN), it was 132.83 ± 6.17 s, 739.09 ± 11.31 s, and 14.53 ± 0.20 min, respectively, which was statistically highly significant ( P < 0.0001) [ Table 2 and Graphs 1 – 3 ].

The highest percentage of kidney pathology in PCR‐positive fish was detected in the 0+ fish age class (85%), this category shows a highly significant difference compared with age categories 1+, 2+ and 3+ ( p < 0.0001), whereas no significant differences were detected among the remaining groups (Table 1 ).

A highly significant correlation (r = 0.475, p <0.0001) was also found between the Ct values of the concordant positive saliva and NPS specimens.

As a result, the difference in mortality remained highly significant ( p < 0.0001).

Decoding of uncued orientations was highly significant on both Switch (1–1.4 s after cue onset, corrected p = 0.0001) and Repeat trials (1.05–1.4 s, p = 0.0028, Switch > Repeat 1.25–1.4 s, p = 0.0295; Fig. 5 A , left panel inset).

This difference in prevalence was highly significant ( P < .0001).

Among them, all DVH (V 5 -V 30 , MLD) and volume (ITV, PTV, TV, LPR) parameters exhibited highly significant between-group differences ( p < 0.0001) and large effect sizes (absolute Cohen’s d > 1).

The correlation between in-vitro PSA survival rates and plasmepsin 2–3 copy number was highly significant ( r =0·83 [95% CI 0·67–0·91], p<0·0001 for plasmepsin 2 copy number and r =0·85 [0·71–0·93], p<0·0001 for plasmepsin 3 copy number).

Furthermore, the clinical score differences on day four revealed highly significant intergroup variations, with P-values of <0.0001 for LPS + DH-HQ vs LPS, 0.0005 for LPS + DH-HQ vs LPS + DH, and 0.0028 for LPS + DH-HQ vs LPS + HQ (P < 0.005) ( Figure 14A ).

The t-test revealed that no significant differences in HI were observed within lines in NIL15-YXZ or NIL15-SBSM ( p > 0.05), but highly significant difference in mean HI was observed between NIL15-YXZ and NIL15-SBSM ( p < 0.0001).

Particularly when UFH was applied, the increase of the ED 50 value was highly significant (15.5 ± 3.3 Gy; p < 0.0001).

Firstly, using geographic origin as a trait, a highly significant association was found ( AI = 8.8954, P < 0.0001; PS = 69.3392, P < 0.0001) ( Table 2 ).

The ANOVA results for the Naphtha cut of heavy oil which are presented in Table 10 , indicate that the model as a whole is highly significant, with a p value of < 0.0001 and an F-value of 1518.48, suggesting that the factors included in the model explain a substantial portion of the variability in naphtha yield.

On comparison of the proportion of the patients requiring only the ST graft, the p value came out to be highly significant ( p < 0.0001), showing that the ST tendon alone is enough when using the weave technique to achieve the required graft diameter.

The results indicate that comparisons evidenced highly significant correlations between values computed by the lumped model and simulated mechanical model for both networks with p < 0.0001.

Regarding age groups, the prevalence of infection was highly significant (p < 0.0001).

Highly significant differences between adjacent and tumor tissues were found by statistical analysis using the Mann–Whitney U test ( p < 0.0001 for all comparisons; Figure 2 A–C).

Note the highly significant (−log10(p)≥4; p≤0.0001) differences for the left and right frontal pole, left and right insula, left and right isthmus cingulate cortex, left and right medial orbital frontal cortex, left and right rostral anterior cingulate cortex, left inferior temporal gyrus, left rostral middle frontal cortex, left temporal pole, right fusiform gyrus, right lateral orbital frontal cortex, and right parahippocampal gyrus.

To further characterize what the changes across time were, a linear contrast of the interaction term was determined and was found to be highly significant (p<0.0001), indicating that the groups made linear changes across time with different slopes.

This difference was highly significant with a large effect size ( t (119) = –5.6, p < 0.0001, d = 0.98).

The discrepancy in values between the two groups was highly significant ( p < 0.0001) in all observation periods (Table 2 ; Fig. 5 B).

9 Analysis of Variance (ANOVA) results for the model showed it to be highly significant overall (F = 427.62, p < 0.0001) (Table 3 ).

θ ST [ 45 ] among all populations was moderate but statistically highly significant (0.069, p < 0.0001; temporal samples from the same populations were pooled).