“highly significant”

anesthesiologic ICUs there was a highly significant difference between anesthesiologic ICUs compared with other disciplines ( p < 0.0001).

Respiratory coupling above .25 Hz was highly significant ( p < .0001; Figure 3A ), whereas cardiac coupling above 1.7 Hz was modestly significant ( p < .0142; Figure 3B ). 3.1 Risk assessment model The individual seizure values underlying Figure S3 served as features for training a logistic model, producing propensity scores for each seizure, which further distinguished SUDEP from non‐SUDEP cases.

This difference was highly significant during ages 4–9 years ( p < .0001), with the largest cluster volume (664 mm 3 ) in the left parahippocampal gyrus at age 9 years.

Experiments that supplemented carotenoids rather than correlations with concentrations of carotenoids in blood resulted in significantly larger effect sizes (p = 0.006), but an analysis without the supplementation studies still yielded a highly significant overall effect size ( table 2 , p<0.0001).

The overall and highly significant (p = 0.0001) genetic differentiation index (Φ st ) was 0.212.

A highly significant difference ( p < 0.0001) was observed between the 2:1 treatment, and both 1:1 and PFOA only treatments, with respect to lethal concentration and apparent neurobehavioral effects, suggesting an effectively reduced toxicity of the fully complexed PFOA.

As shown in Table 2 , the model selected by the test was highly significant ( p < 0.0001).

A highly significant relationship between the presence of C. difficile toxins and IBD, both active ( p < 0.0001) and inactive ( p < 0.0001), was observed.

Box-Behnken design analysis yielded a highly significant quadratic model ( P < 0.0001) with a non-significant lack of fit ( P = 0.5929), indicating excellent model adequacy and reliability (R 2 = 0.9962).

A highly significant ( p < 0.0001) decrease from t0 to t1 was observed in: oxidized glutathione (−56% vs. −79%, Figure 2 A); oxidized Cys (−34% vs. −24%, Figure 2 B) and oxidized CysGly (−44% vs. −47%, Figure 2 C) for group GluReS compared to group GluS, respectively.

Again, nearly all comparisons were highly significant ( p < 0.0001) with the exception of mosquito interhost A-U mutation ( p > 0.05) and avian interhost U-A mutation ( p < 0.05), indicating that transition and transversion mutations are not uniformly distributed across the samples ( Table 2 ).

Correlations between independent measurements of Lim3A transcripts were highly significant across the 16 lines in both embryos (P<0.0001) and in heads (P = 0.0074), strengthening reliability of the results.

Accordingly, the second-order polynomial equation was established as follows: Y = − 9.16012 + 0.123691 × A + 0.143075 × B + 0.162185 × C − 0.0001375 × A × B − 7.5 × 10 − 5 × A × C + 3 × 10 − 5 × B × C − 0.0014058 × A 2 − 0.0013893 × B 2 − 0.0015433 × C 2 From Table 2 , it is evident that the model’s regression is highly significant ( p < 0.0001), with a lack of fit of 0.3369, exceeding the significance threshold of 0.05.

The difference in DOC between the vaccinated and unvaccinated groups was highly significant prior to DOC matching (Student’s t , p < 0.0001).

Though lyso-Gb1 values at enrollment were widely distributed, they displayed a moderate and statistically highly significant correlation with disease severity measured by the GD-DS3 scoring system in all GD patients (r = 0.602, p < 0.0001).

Once again, Gnetin C exhibited the most profound effects in both cell lines and highly significant inhibition of cell migration ( p < 0.0001) compared to Res and Pter ( Figure 3 C,D). 3.3.

This analysis revealed highly significant main effects of dose (F 4,160 ≈ 848.5, p < 0.0001), wavelength (F 1,160 ≈ 252.2, p < 0.0001), and cellular age-status (F 1,160 ≈ 1466.8, p < 0.0001), indicating that metabolic activity varied significantly with PBM fluence, irradiation source, and replicative aging.

Metastases were present in 16.67% of surviving patients and 54.55% of non‐survivors, with a highly significant difference noted in the statistical analysis ( p < 0.0001).

A highly significant cytotoxic effect ( p < 0.0001) was also identified in both cell lines, at 100–700 μM in MDA-MB-231 and 100–400 μM in MDA-MB-468.

Statistical analysis showed a highly significant influence of genotype on the magnitude of the heterosis effect ( F = 4.59; P < 0.0001; Fig. 2 ), validating this approach.

The Friedman test was highly significant (p < 0.0001, Friedman chi 2 = 116.97, df = 3, Kendall’s W = 0.6045).

The criterion for significance was set as p < 0.05, and highly significant differences in the statistics were accepted if p < 0.0001.

GDF-15 showed the most robust response, with highly significant main effects for both time and dose and a strong interaction ( p < 0.0001).

The test revealed a highly significant association (χ 2 (38) = 3616.46, p < 0.0001, V = .12), indicating that the SOC profile of ADRs varies substantially depending on the anti-EGFR agent.

In animals subjected to the streptozotocin protocol (STZ-DPN), there was a highly significant ( p < 0.0001) reduction (95%) in PWT (>0.12 g i.e., static mechanical allodynia) which was restored to a level that was comparable to the saline-treated group (>2.5 g) by the dose of gabapentin (75 mg/kg) as the positive control standard drug ( Figures 1A–C ).