“highly significant”

However, the correlation of body weights of mice at 8 wk of age fed a low-fat diet to the change in fat mass from 8–12 wk of age was highly significant ( R = 0.364; P = 7.99 × 10 −05 ).

The difference between the green control sample and the green experimental sample is highly significant using a two‐tailed t test ( p = .00008).

The differences between the repair techniques were highly significant for both parameters: force at failure ( p = 0.00008) and stiffness ( p = 0.002) (Fig. 3 ).

The difference was highly significant (P = 0.00008, unpaired t test).

In the control group there was a highly significant difference between the Same-Function and Cross-Function relationships [ t (15) = 5.4, P = 0.00008] whereas this comparison did not approach significance in the ASD group [ t (15) = 0.9, P = 0.4].

These differences in CD4 and CD8 compartments were significant by ANOVA (Table 2 ), with the most highly significant differences being in the CD8+ IFNγ+ subset ( p ≤ 0.00008).

The area under these facilitation curves was 57.4 ± 2.8 in WT slices and 33.3 ± 3.3 in Tg2576 mice, a highly significant difference (P < 0.00008, unpaired t-test).

Only one of the 1089 ligand/receptor screens for these dRy variants was positive, in contrast to 102 of 8815 screens for sequences having this Arginine, which is a greater than 12-fold enrichment and highly significant (hypergeometric p-value = 8 × 10 −5 ; Table S4 ).

When we divided the entire population into three groups—normal body mass index (BMI; <25 kg/m 2 ), overweight (25≤ BMI <30 kg/m 2 ), and obese (BMI ≥30 kg/m 2 ) individuals—the predictive performance of the 7 loci was greatest in the group of obese individuals, where the net reclassification improvement was highly significant (0.51; P =8.00×10 −5 ).

However, we found a highly significant positive relationship between persistent learning on day 1 and 24-h retention (slope = 0.80, r = +0.71, F(23,1) = 22.9, p = 0.00008).

SOX4 , the most proximal gene showed a highly significant association between gene copy numbers and gene expression (ρ = 0.59, p<8×10 −5 ), as did CDKAL1 (ρ = 0.78, p<3×10 −16 ).

Following a 10-fold cross-validation Lasso regularization and step-wise refinement of parameters in the regression model, the overall explanatory power of the resulting model, as shown in Figure 1 : PRS ∼ 1 + QTcB + TPEcR + TWAcR * TWDcR, was modest with R 2 = 0.09, and model fit was highly significant (F-stat = 5.5, p = 0.00008).

The Student's t-test of the differences in 13 C enrichment at 20–60 min after the pulse and in the initial 13 C accumulation rate at 0.5–10.0 min showed that these differences were highly significant in both cases, p = 0.00008 and p = 0.050, respectively.

The difference between the changes in gamma energy was highly significant [t(886) = 3.96, p = 8.06e-5].

The highly significant association ( P ≤ 8.17 × 10 −5 ) between seed length to width ratio and TcSNP 733 on chromosome 5 was verified with FarmCPU ( P ≤ 1.12 × 10 −8 ).

Furthermore, AGPAT1 was still highly significant ( P = 8.2e-05) in a meta-analysis of variables adjusted for age and the use of thiopurines.

On chromosome ten, we identified a highly significant SNP at 9.55 Mb (ud10000588, P value = 8.27E-05) across all accessions and another significant SNP (id10002607, P value = 1.63E-04) 170 kb farther away (Fig. 2a ).

The reduction of intervertebral disc height was highly significant ( p = 0.000083), undoubtedly due to body weight and muscle activation [ 11 , 14 , 17 ].

As indicated by the values: combined gene signature increased the statistical power of this signature with a highly significant p-value=8.3e-05 and HR=1.84 (1.35-2.51) ( Figure 2A ) to predict disease RFS or recurrence.

For the sleep duration, the overall model was highly significant ( R 2 = 0.30, F (5, 71) = 6.17, p = 8.39 × 10 −5 ).

Combined across all replication groups, the gene-based test for SPATA13-AS1 was highly significant (p=8.40 × 10 −5 ), and the statistical association was even stronger when the discovery set was included in the combined analysis (p=7.38 × 10 −7 ).

The correlation analysis revealed a highly significant positive correlation between RT-qPCR and RNA-seq data at R-6 h ( r = 0.95 and P = 8.5 × 10 –5 ) and S-6 h ( r = 0.96 and P = 9.8 × 10 –5 ), indicating methodological reliability and supports the consistency of the RNA-sequencing data (Fig. 8 A-H).

Remarkably, PRRT2 displays a highly significant excess of nonsynonymous (pN) vs synonymous (pS) mutations in Asia (pN/pS = 4.85) and Europe (pN/pS = 1.62) compared with Africa (pN/pS = 0.26; Asia vs Africa: P = 0.000087; Europe vs Africa P = 0.00035; Europe vs Asia P = P = 0.084).

We observed a highly significant increase in adjusted R 2 with the addition of ICA2 to the model ( F (1,507)=15.6, P =8.8 × 10 −5 ).

A paired Wilcoxon signed-rank test confirms that the difference is highly significant, with p = 8.86 × 10 − 5 and a rank-biserial effect size of r rb = − 1.00 .