“highly significant”

We observed a highly significant positive correlation between MSI/hypermutation frequency and the total number of somatic mutations per cancer after integration by OncoMerge (R = 0.68 and p value = 2.0 × 10 −5 ).

Indeed, used alone, CD9 based sorting yielded a highly significant, 14-fold enrichment in CD140a + /PDGFRα + cells relative to their unsorted dissociates (t-test, p=0.00002).

The observed difference in the monthly prevalence of the DEC was highly significant in the month of March (P = 0.00002) ( Table 3 ).

The difference between the cumulative growth in the number of PVCs in the control and riluzole groups was highly significant, at p<0.00002.

For the lodging-resistance trait, eight true SNP markers were detected in the five loci located in chromosomes 1В, 2А, 3А, 3D and 6А as per the physical mapping of reference bread wheat variety sequence IWGSC RefSeq v1.0. Highly significant ( p < 0.00002) associations were observed for loci QLdg.icg-1B and QLdg.icg-2A in chromosomes 1B and 2А, respectively (see Table 2).

ID 653 was therefore experimentally regrouped into the viral group, which resulted in a highly significant p-value ( p = 2e -5 ; Fig 7B and 7D ). 3.2.2 Bacterial No statistically significant group differences could be detected for bacterial presence in this investigation.

However, the overall difference for these three genes is highly significant (Chi-squared test, P = 2e-5).

For the U-87 MG glioblastoma cell line, on which the present study was focused and for which correspondingly more experiments were performed, the enhancement was statistically highly significant ( p = 2 × 10 −5 ).

There was a highly significant effect of temperature on population size ( F 2,9 = 43.6, p = 0.00002), with the 30°C treatments having the highest numbers of adult moths and the two 33°C populations which persisted having the lowest.

As expected, we see highly significant enrichment of terms related to influenza (Fig. 7 a) including Transport of Virus ( p = 2.0 × 10 −5 ), Influenza Life Cycle ( p = 5.8 × 10 −4 ), and Influenza Infection ( p = 7.7 × 10 −4 ).

The log-rank test for a difference in the CIF for GFNA between recipient age <50 and ≥50 years was highly significant, yielding p = 0.00002.

In marked contrast, in the three other quartiles there were highly significant correlations between ALK7 and INHBB expression ( p < 2 × 10 −5 for each of the three quartiles after adjusting for sex and age).

We also observed a highly significant difference in allele frequency between the Benin and Yoruba samples (HapMap Project) for the SNP rs3130315 (p = 2 × 10 -5 ) and between the Mongolian and Han Chinese samples (HapMap project) for two SNPs: rs9562080 (p = 0.047) and rs4116821 (7.36 × 10 -11 ).

Negr1 -WT mice demonstrated improvement in the time required to find the hidden platform (escape latency) over the first three training days and there was a highly significant improvement from day 1 to day 3 ( p = 0.00002).

Interestingly, the rs3813065 SNP was associated with a highly significant difference in the expression of endoplasmic reticulum aminopeptidase 2 ( ERAP2 ) in the HapMap cell lines derived from the African Yoruba population ( P = 2 × 10 −5 ).

The difference in FITC MFI after stimulation was statistically highly significant ( P = .00002) ( Figure 4 ).

All model terms were highly significant ( p < 2e − 5), with acidic group count (nAcid) displaying the most significant effect ( p = 3.2e − 7) (Fig. 2 e), consistent with the group-wise investigation of LMs (Fig. 2 a).

Effect of seed treatments with bacterial endophytes on OSR yield, growth and disease incidence under commercial field conditions (Poříčí, Czech Republic) Except for a highly significant (P = 0.00002 and P = 0.00033, respectively) reduction of stress symptoms (red discolouration of leaf margins) by both IP and IG inocula in early spring (March 2017; Table 2 ) none of the seed treatments with bacterial endophytes affected growth, yield and diseases of OSR significantly under commercial field conditions.

Importantly, we also observed a highly significant inverse correlation with the expression of AR (P = 0.00002) (Figure 1 A).

Strikingly, ontological analysis established that six of the 17 CIS genes have transcription factor activity ( Nfia , Tead1 , Tgif2 , Nfib , Myt1l and L3mbtl4 ), a highly significant excess relative to expectation (FDR corrected p-value = 2×10 -5 ).

This analysis indicates that the 33 genes identified in our study represent a highly significant level of overlap ( p < 0.00002).

The bin spanning R 2 = 0.98–1.00 — centered on Rc—exhibits a highly significant dip test (p = 2.1 × 10 −5 ; GMM-BIC: two components), directly capturing the symmetry-breaking transition at the bifurcation point.

The difference between stimuli remained highly significant ( F (1,43) = 23.69, p = 2·10 −5 , η 2 = 0.137, η p 2 = 0.355), in accordance with vestibular enhancement.

One SNP (GGaluGA348872), located at 1.87 Mb on GGZ, had highly significant association with IMF Br (p = 2.14 × 10 -5 ) and is located 122.3 Kb upstream of the kinesin heavy chain member 2A ( KIF2A ) gene.

A highly significant ( p = 2.2 × 10 −5 ) OPLS model could be built for the classification of samples by production year (model 8).