“highly significant”

Ego-Dissolution Inventory (EDI) and Mystical Experience Questionnaire (MEQ) A paired comparison using the EDI revealed highly significant larger total scores for DMT compared to placebo ( T = 6.98, df = 12, p = 1.47e -5 , Cohen’s d = 2.67).

The association of rs3815087 remained highly significant even after correcting for multiple comparisons, both at allelic (FDR corrected p = 1.48 × 10 −5 ) and genotypic levels (FDR corrected p = 2.05 × 10 −5 ) while for other SNPs, this association was lost after multiple corrections.

This hypergeometric analysis indicates that the 4.1 fold greater enrichment in the RAG/CsNp genes was highly significant (p = 0.000015) whereas there was no overall change in growth factor receptor genes (-1.1 fold, p = .42) and significantly fewer genes were found in the apoptosis gene group than expected by chance alone (-2.2 fold, p = .02).

Conversely, all individual variants identified in our analyses showed directionally consistent effects in a meta-analysis of two European-ancestry studies of extreme longevity, and a test of association of a polygenic risk score of the variants was highly significant in the longevity dataset (p < 1.5 × 10 −5 ).

Strong and extensive pairwise LD was observed among highly significant SNPs around AX-177640219 ( p -value = 0.000015) on chromosome Araip.B08 from the 12,629,161 to 13,029,161 bp region ( D’ > 0.80) in which D’ varied from 0.036 to 1 ( Figure 5 d and Supplementary Table S5 ).

Both CCL17 ( Figure 1A ) and CCL18 ( Figure 1B ) expression were highly significant when analyzed in rank order based on Ridley-Jopling classification (non-parametric trend test, P = 1.5×10 −5 and 3.0×10 −8 , respectively).

Case-control genotyping and association tests in the entire GWAS discovery cohort (n = 44) showed highly significant association of the IAR phenotype with FKBP6 SNP g.11040315G>A ( P = 1.51E-05), and significant association with SNP g.11040379C>A (p.166H>N; P = 0.004) ( Table 3 ).

The two-way ANOVA revealed a highly significant interaction between genotype and condition ( p = 1.53 × 10 −5 ), indicating substantial variability in carbon assimilation responses among genotypes.

Analysis of nucleotides coding for these 24 OB domain residues identified one non-synonymous change in 6,498 control exomes 14 compared with three in 105 melanoma families, emphasizing a highly significant enrichment of variants in the melanoma cohort ( P = 1.54×10 −5 ) ( Online Methods , Supplementary Tables 6 - 7 ).

The difference is best seen in energy of alpha frequencies in the right frontal and central region, which is highly significant ( P = 1.6 × 10 -5 , P = 2.6 × 10 -5 ).

Among upregulated biological process, proteolysis is the highly significant ( P = 1.60E-05) biological process and it was observed that, 22 genes involved in proteolysis were upregulated in crossbred testis (Fig. 2 ), which includes serine proteases, chymotrypsin like elastases and matrix metallopeptidases.

Mature B cells were not only able to distinguish between these groups in the class switched category, but also in the non-class switched category where the difference between TB and OLD was highly significant ( p = 0.000016) and between TB and the healthy control group where p = 0.025939 (not shown)).

This observation is supported by strong statistical evidence, with highly significant differences among PLGA conditions (ANOVA p = 1.61 × 10− 5 ; Kruskal–Wallis p = 7.3 × 10− 4 ).

The differences were highly significant ( p = 1.65e−05), whereby diploids possess ~6% of duplicated gonial cells, while HHL and HLL triploids had none.

Shapiro-Wilk normality test had a non-significant value ( p -value 0.1024) for the transformed data, while, it was highly significant for the original data ( p -value = 1.688e − 05 ) indicating the non-normal distribution for the original common bunt scores.

There was also highly significant difference among the three different genotype groups in terms of total morphine self-administered (p = 1.7 × 10 -5 ) and weight-adjusted morphine (p = 6.6 × 10 -5 ) (Table 1 ).

ANOVA analyses of the treated leaves demonstrated highly significant effects of both sesquiterpene ( P = 1.70e -5 ) and application method ( P = 6.31e -5 ) on blade area ( Figure 8b ).

3.2.4 Cameroon For SNPs present in three or more mosquitoes, the most highly significant SNP was in the cytochrome P450 CYP304B1 on chromosome 2 ( p = 1.7 × 10 −5 ).

Specifically, the pairwise comparisons of effect sizes across body sites revealed a moderate and highly significant correlation between saliva and plaque (Pearson r = 0.30, p = 1.7 × 10 −5 ; Spearman r = 0.28, p = 8.2 × 10 −5 ).

This analysis showed significant effects of both Instrument ( p < 8.28 × 10-5 , F = 19.68) and ROI ( p < 2.42 × 10-2 , F = 5.53), as well as a significant Instrument x ROI interaction ( p < 1.03 × 10-6 , F = 34.47) driven by a highly significant difference between cello playing and singing in hand motor regions ( p < 1.71 × 10-5 , F = 33.6).

The fact that we have 11 genes using exon2 (falls outside the chart) is highly significant statistically (p = 1.718378e-05).

A case/control series in hepatitis C related disease demonstrated highly significant detection (p<1.72*10 −5 ) of patients at high risk of developing HCC.

R s , VWC, and T s were all higher in eCO 2 than in aCO 2 ( Figure 1 ) which resulted in a highly significant interaction effect of VWC and T s ( p = 1.73 × 10 –5 ) that explained 31% of the variability in observed R s ( Table 1 ).

When Triticeae was marked as the foreground branch, the likelihood ratio test (LRT) was highly significant (P = 0.000017894).

The survey revealed that there was a highly significant difference between diameter classes of wood exploited (f = 12; df = 2; p = 0.000018) (Figure 4 ).