“highly significant”

Increasing UF volume or dialysate flow led to a highly significant increase in IL-1 receptor antagonist and IL-6 clearance rates ( P < 0.00001).

1 , Supplementary Figure S1 ).The modules were numbered in increasing order from 1 to 30 according to scores of the clustering algorithm 15 (Supplementary Table S1 ); 1 is assigned to the module with the highest score (most densely connected to each other).Next, we assessed whether genes of the clustered terms are significantly interconnected in physical interactions by comparing each of 30 modules with randomly generated networks having the same gene number of the corresponding module and confirmed the highly significant inter-connectivity of them 12 (Supplementary Figure S2 , S3 , p < 0.00001), meaning that their components are not randomly distributed in the interactome.

The overall Pearson correlation between the Caprini and Padua scores was only moderate, albeit highly significant (r = 0.619, p < 0.00001).

Hence, we detected a highly significant ( P < 0.00001, Fisher's exact test) correlation between trees homozygous for the acro ‐SNP and the early cone‐setting phenotype.

The unpaired Student’s t-test revealed a highly significant difference in PNP biodegradation between the compared conditions, with a p-value < 0.00001, indicating statistical significance well below the 0.01 threshold.

The positive relationship between φ and geographical distance was statistically highly significant (Mantel test, 100000 randomisations, r = 0.375, P = 0.00001), also when corrected for beetle phenotype (Partial Mantel test, 100000 randomisations, r = 0.379, P = 0.00001; see Materials and Methods for comments regarding the value of r of the Mantel test).

DAVID 6.7 ( 17 ) and Enricher ( 18 ) were utilized to annotate the highly significant remarkable ( p < 1 × 10 −05 ) genes for functional implications. 3.

The P value for preoperative and postoperative difference in Munk score and FDDT score was highly significant ( P = 0.00001).

We found 449 genes common to both DEG sets of mouse Lhx2 cko and PRDM16 mutant organoids, which is highly significant based on hypergeometric statistics showing a representation factor 55.3 with a P -value < 0.00001 (see Methods) ( Supplementary Fig. 4D ).

Large and highly significant pairwise matrilineal differentiation was found among adult sharks from the GAL, SEY, and FLA ( F ST = 0.529–0.738, Φ ST = 0.781–0.953, p < .00001; Table 2 ), along with strong phylogeographic structure and no haplotype sharing among sampling sites (Figure 4a ).

The outcomes of the study outlined a statistically highly significant negative correlation between the level of education and drug use (Pearson test, R (38) = −0.9282; p < 0.00001).

The changes in the right prefrontal Oxy‐Hb had a highly significant positive correlation with the changes in the left prefrontal Oxy‐Hb ( γ = 0.995, P < 0.00001).

graminis cultures were positively correlated with one another and very highly significant ( P = 0.00001) ( Table 2 ).

Prep1 DR induced a 2-fold increase of highly significant DNA-binding sites (p < 10 −5 ) in P versus C cells before differentiation at day −2, and a further 2-fold increase 4 hours after induction of differentiation (Fig. 4B and Supplementary Fig.

Interestingly, investigation of intragenic relationships between VastDB AS events reveals that pairs of cassette exons (especially in the case of neighboring exons) and pairs of retained introns within the same gene show highly significant correlation of inclusion or retention levels across samples from each species ( P < 10 −5 , Wilcoxon rank-sum test) ( Supplemental Fig.

Prevalence of SNOCIs who presented with solitary positive anti-HCV IgG antibody in non-viremia patients (34.82%) was highly significant (higher) compared to prevalence of COCIs (3.125%) in negative controls for both IgG antibodies and viremia ( p < 0.00001).

This difference, favoring the untreated patients, is highly significant ( P < 0.00001). 19 Hematomas are not inconsequential. 11 Blood transfusions should rarely be needed for cosmetic surgery patients.

Though the differences were small, particularly on the original task, they were highly significant (P < 10 −5 ).

As was the case with secretion, the differences in cell retention for wild-type and mutant versions of Wnt1 are highly significant (p<1×10 −5 ).

The deviation from Hardy-Weinberg equilibrium is highly significant ( P < 10 −5 , Fisher’s Exact Test 40 ) with a complete absence of heterozygotes.

A total of 90 highly significant QTL (245 SNPs; p < 10 −5 ) were identified for salinity-related traits with the strongest associations detected for root Na + content followed by root Na + :K + ( Fig 2A and 2B , respectively).

Scores from PCA were normally distributed ( p > 0.2), and the DFA among the 19 locations was highly significant (Wilks’ Lambda: 0.44442, F (33,922) = 8.8617, p < 0.00001, n = 533).

The log 10 Bayes factors recovered under each substitution model exhibit very highly significant linear relationships ( r 2 > 0.99, p < 0.00001 in all cases) and are hence independent of the amino acid substitution model employed (electronic supplementary material, S7).

Hardy–Weinberg equilibrium analysis for rs2904880 revealed highly significant deviation from expected genotype counts ( χ 2 = 161.4, df = 1, p < 0.00001), characterized by a marked heterozygote deficit (observed 271 [22.66%] vs. expected 428.36 [35.82%]) and a reciprocal homozygote excess.

Subgroup differences were highly significant (Chi 2 = 754.79, df = 5, p < 0.00001; I 2 = 99.3%) ( Figure 5 ). 3.6.