The statistical analysis revealed highly significant differences between the tested enterotoxin genes and virulence genes with p=0.00001.
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All included factors exhibited highly significant P -values ( P < 0.00001), indicating strong statistical validity ( Figure 10 ).
In both cases, the calibration curves showed a highly significant linear response over a concentration range spanning two orders of magnitude ( R 2 > 0.99; p value < 10 −5 ; Fig. 3b, c ).
Heterogeneity analysis revealed highly significant heterogeneity (I 2 = 93%, p < 0.00001), thus a random-effect model was used for statistical analysis.
The linear-regression analysis between the number of CAG repeats in the expanded allele and age at onset was highly significant ( p < 0.00001).
The differences were highly significant in the Z-test ( p < 0.00001) for African American and Latino populations.
We observed a strong and highly significant overlap of 516 genes (Monte-Carlo empirical P < 10 −5 , normal approximation P < 10 −300 , Additional file 1 : SI Fig.
There was a statistically highly significant ( P < .00001) association between low serum zinc levels and WHC grades of HE.
Overdose showed significant reductions from pre-operative to post-operative measurements, and the Nemo prognostic model was close to the final post-operative condition as reflected in the highly significant ANOVA (F = 13.66, p < 0.00001).
With the exception of “CSF-Aβ38” and “CSF-Aβ40” all showed strong and highly significant association with markers in the APOE region but no better than suggestive ( P < 1E-05) signals in the remaining genome (see Supplementary Figs. 3 – 7 and Supplementary Tables 7 – 11 ).
This trend is highly significant ( p < 1 × 10 −5 ; two-sided permutation test).
This was also highly significant ( p <0.00001).
The results indicate a nonsignificant trend toward left-sided tinnitus ( P = .07) and a highly significant association between ear-piece location and tinnitus location ( P < .00001).
Table 2 shows the intergroup and intragroup comparisons between Group A and Group D using one-way analysis of variance wherein a significant difference was observed between all four groups when intergroup and intragroup comparisons were made, while the results were found to be statistically highly significant ( P < .00001).
A posterior-dominant pattern of ‘neural slowing’ was observed, with increased theta band power in PD that was highly significant ( p < 0.00001), as well as a spatially similar concomitant decrease in gamma-band activity ( p < 0.00001)—in other words, an increase in low frequency activity and a decrease in high frequency activity.
In fact, both correlations are highly significant (p < 0.00001 for each in Fig 2B ).
The overall effect of surgery compared to sham surgery was highly significant (SMD 0.34, 95% CI 0.20 to 0.49; p<0.00001), while heterogeneity was large (I 2 =67%, p<0.00001).
This difference is highly significant (two-proportion z -test, p < 10 −5 ), and it yields a ratio for the fixation rate of IS-related mutations per generation in mutator versus non-mutator lines of 0.46.
This difference was highly significant (χ 2 = 30.12, P < 0.00001), with a RR of 7.14 (95% CI: 3.58–14.23), suggesting that tubing obstruction may significantly contribute to urinary stasis and infection.
This difference was highly significant (OR = 50.9, [8.6, 2060.0], p value < 0.00001) (Table 2 ).
At 0% the low α-diversity of phototrophs was highly significant to diversities at 20% (June) (t = −8.85, df = 12, p < 0.00001 ) and at 45% (December) intermittence (t = −8.4, df = 21, p < 0.00001 ) ( Table S5 ).
none of the fertile controls, a highly significant difference (P<0.00001).
The unpaired Student’s t-test revealed a highly significant difference in PNP biodegradation between the compared conditions, with a p-value < 0.00001, indicating statistical significance well below the 0.01 threshold.
Our study therefore demonstrated highly significant ( p < 0.00001) recovery of a VH3-enriched set of B cells and our findings therefore confirmed the selection of SpA-binding switched post-germinal center B cells that was solely based on the VH region and was apparently not affected by light chain usage.
5 C, D indicated that the correlation between estimated and ground-truth EC was highly significant ( p < 1e-5) for low NSR (NSR < 0.3) and remained significant ( p < 0.005) even for large NSR (NSR ≥ 0.3).