“highly significant”

Correlation analysis showed a highly significant linear positive relationship (R 2 = 0.466; p < 0.00001) of plasmatic B4GALTs with age from infancy to centenarians (Figure 1A ).

Highly significant (P < 0.00001) pairwise correlations were observed for 431 out of the 703 possible pairs for the 38 probesets examined in this study.

Regression analysis revealed a highly significant relationship between 28S and 18S copy numbers ( R 2 = 0.996; P < 0.00001; Supplementary Fig. 1 in Supplementary File 3 ), with a regression coefficient close to the expected value of 1 (1.02).

This study showed that duration of analgesia was 37% higher for Bupivacaine which lasted for up to an average period of 7.3 hrs which was highly significant (p=0.00001*).

For dentin permeability, the Nd: YAG laser group differed significantly from the EDTA gel group ( p = 0.0032), while the combined treatment group showed highly significant differences compared with both the EDTA gel group and the Nd: YAG laser group ( p < 0.00001).

In multivariate analysis, a significant correlation between CRE acquisition and weeks of hospital stay was seen ( p < 0.001), however not with healthcare cost, the latter likely due to highly significant ( p < 0.00001) co-variation between healthcare cost and weeks of hospital stay.

Results Copper levels were higher in group II showing statistically highly significant results compared with that of group I with p ≤ 0.00001.

Predictive Value of the First Injection on Long-Term Outcome There was a highly significant (r = 0.855, p < 0.00001) correlation between the outcome 30 days after the first injection and the outcome after one year of continuous 3-monthly injection therapy for the pRoMs ( Figure 3 A).

The difference in the concordance of these 2 data sets was highly significant (p<0.00001).

2b ), but, when accounting for differences in site location, there was a highly significant difference in the mean percentage of ARB for the antibiotic types (χ 2 =25.5, df=2, P =<0.00001) ( Fig. 2c ).

Here, we detected a total of six highly significant association signals ( p < 1 × 10 −5 ) for i-LT, corresponding to five unique genes, consistent with a previous report ( Supplemental Table 7 ) ( Wei et al., 2018 ) and suggesting the potential importance of these candidate genes for final PH in maize.

The combined group demonstrated a substantially larger and highly significant positive effect (SMD = 2.02, 95% CI: 1.83 to 2.21; P < 0.00001).

The increments in luciferase activity produced by the addition of increasing amounts of human rMCP-1 to antigen stimulated cells were significant for the allele 1G (ANOVA F = 10.23, p = 0.005) and highly significant for the allele 2G (ANOVA F = 172.3, p <0.00001).

Association study Supplemental Figure s1 illustrates a highly significant correlation ( P = 0.001%) between grain filling rate and heat susceptibility index with grain yield.

This represents a highly significant association between in planta induced putative effectors and H3K27me3 domains (χ 2 = 45.217, p < 0.00001, S8 Table ).

This difference was highly significant (χ 2 = 30.12, P < 0.00001), with a RR of 7.14 (95% CI: 3.58–14.23), suggesting that tubing obstruction may significantly contribute to urinary stasis and infection.

There was no significant difference in MM96L when siNF1 was compared with miR-514a, whereas in MM253, particularly at higher drug dosage (10-100nM), the differences between siNF1 and miR-514a, were highly significant ( p < 0.00001) (Figure 5a ), indicating that the mode of BRAFi resistance was different, possibly due to other targeted genes of miR-514a.

The production of potentially phased siRNAs alone is, however, not enough to class a locus as trans -acting so we concentrated on the 12 predicted highly significant loci with p values < 0.00001 and used the psRNATarget prediction tool [ 40 ] to identify potential targets for phased siRNAs (Table 2 , Additional File 6 ).

Also, the random effect of study was highly significant for the half‐life analysis ( p < 0.00001), but there was no significant random effect of study for the percent recalcitrance model ( p = 1).

In a meta‐analysis of six studies of CRT, the 95% CIs for the improvement in peak VO 2 with CRT went from 0.32 to 3.22 mL/kg/min, with borderline significance, P = 0.017, 35 compared with the narrower CI, and more highly significant effect seen here: 95% CIs for the improvement in peak VO 2 with CCM between 0.56 and 1.30 mL/kg/min, P < 0.00001, giving a considerably more precise estimate of efficacy and of increased statistical significance.

Despite the relatively low statistical power owing to the small sample number, if one assumes a normal distribution of the control values, the difference between the control and patient values is highly significant (SD >5, P =10e-6).

In exploring the subgroup for tensile strength ( Table 4 ) there was a highly significant difference ( P < 0.00001) when nano filler was added to the material, however there was no significant difference when micro fillers were added ( P = 0.74). 3.1.2.

This difference, favoring the untreated patients, is highly significant ( P < 0.00001). 19 Hematomas are not inconsequential. 11 Blood transfusions should rarely be needed for cosmetic surgery patients.

The diverging instrumental effects of DBP and SBP on migraine were also supported by restricting analysis to SNP instruments that were non-significant ( P > 0.05) for one measure but highly significant ( P < 1 × 10 −5 ) for the other (Supplementary Fig. 28 ).

A relatively small number of the correlations were strong ( R > 0.4) and highly significant ( p < 1e−5 and FDR < 0.016) (Fig. 4 a).