“highly significant”

In pairwise comparison, no difference in VAS between Pfizer and Moderna was found ( p = 0.49), whereas the difference in VAS between both the Pfizer and AstraZeneca vaccine and the Moderna and AstraZeneca vaccine were highly significant (for both pairwise comparisons p < 0.000001).

Upon initial analysis, the storage process demonstrated a highly significant effect (Hotelling multivariate p-value = 1 × 10 −6 ).

Although this pattern is consistent with the expectation that more functionally important genes (i.e., those that are more highly expressed) will exhibit reduced rates of introgression, these effects explained a negligible proportion of the variance (R 2 < 0.01 for both Asian and European data sets), and the relationship between mitochondrial targeting and introgression remained highly significant after controlling for this measure of transcript abundance ( P < 1 × 10 −6 in both Asian and European data sets).

The three analyses along the diagonal of the graphic are all highly significant ( p < 1 × 10 −6 ), indicating that the CP-LRT found an effect in each disease against disease-causing RV + status in the respective gene.

As expected, highly significant enrichment was observed in the mutant cells for ‘Wnt Receptor Signaling’ (p < 1e-6).

Separation among individual genomes into FREE and PATH distributions along the LDA axis was highly significant (p<10 –6 indicated by the gray box).

A total of 151 genes were regulated by hypoxia in both datasets (Figure 1D ), and a permutation test revealed such an overlap between the two datasets was highly significant ( P < 1 × 10 −6 ; Supplementary Figure S1B ).

Specifically, the evidence grading criteria were as follows: If the association was supported by a highly significant random-effects ( P < 10−6, a threshold considered to substantially reduce false positive findings) 10 – 13 , a sample size of more than 1000 cases, P < 0.05 in the largest study, I2 < 50%, absence of small study effects, a PI excluding the null, no evidence of excess significance bias, and P < 0.05

Similarly, ‘IBD Region’ (left colon, right colon, rectum, sigmoid, transverse, ileum) showed highly significant associations in UC and CD ( p < 0.000001), indicating that anatomical location of involvement may be another important component of the molecular heterogeneity underlying IBD.

We find subtle, but highly significant (p < 10 −6 ) differences in relative height and relative radius between the two populations ( Fig. 2e, g ).

In confirmation of our hypothesis, there was a highly significant, 9.4-fold, increase in the maximal tetanic force (7.5±0.94 g versus 0.8±0.2 g; p=≤0.000001) elicited by ONS in the engrafted OST group of SOD1 G93A mice at late-stage disease, compared to age-matched untrained SOD1 G93A mice (132.4±6.8 days versus 133±6.9 days; n=7 and 11, respectively; Figure 5C–G and Appendix 1—table 3 ), although OST did not alter contractile rate characteristics ( Figure 5—figure supplement 5A–C ).

In such a comparison (Figure 1) it will be observed that the distributions appear quite different; the mean AFTPs have a highly significant difference (t = 10.6, P< 10-6, d.f. = 1.721).

A very highly significant increase of Ang‐2 concentration ( p < 0.000001) was observed in CSF of MA patient in comparison with CTRL subjects (Fig. 1A ).

However, substantial between-country variability was observed, with highly significant differences in seroprevalence rates among country–decade combinations (χ2 ≈ 58,742, df = 23, p < 0.000001).

Notably, the TCT:M2TAM ratio was highly significant ( p ≤ 0.000001) in two HGSOC cohorts.

For each breed, SNPs with a minor allele frequency (MAF) lower than 1% or with a highly significant deviation from Hardy–Weinberg proportions (p < 1.0 −6 ) were excluded.

SNP with call rates < 0.98, minor allele frequencies (MAF) < 0.03 and highly significant deviations ( P < 10 -6 ) from Hardy-Weinberg Equilibrium (HWE) were also excluded.

These studies reported robust sample sizes, highly significant p -values ( p < 10−6), and statistically significant results in the largest included studies.

A highly significant difference in conversion rates was observed between the two groups (log‐rank p < 10 −6 ).

Among these, nfa23460 , nfa38830 , nfa43970 , and nfa9390 exhibited highly significant differences (P < 0.000001).

In contrast, highly significant differences were observed among the crop species (F 2,18 = 615.70, p < 0.000001; Table 1 ).

the nascent bond show that all of these active site dynamics are highly significant with p < 10 −6 ( Fig.

The difference between CD24+/CD44- and CD24-/CD44+ cells with respect to their position in the E-M state space was highly significant (p<10 –6 ).

Note that the difference in PS rates is highly significant ( P < 10 −6 ). 10 μg of protein isolated at 1 h was processed by 8%PAGE/SDS for fluorographic auradiography with PPO.

The differences among the three classes were highly significant (overall differences tested by ANOVA: F 2,141 = 19.5, P<10 −6 ; pairwise t tests: least significant p value <10 −3 ).