“highly significant”

The Phi test for recombination was highly significant ( p =10 −6 ).

Global analyses identified a total of 2,053 sites with overlapping peaks, and statistical analyses showed that this overlap is highly significant ( Figure 2 B) (p < 10 −6 , calculated using a permutation test with 1.0 × 10 6 iterations).

All results were highly significant with p < 0.000001 for all values.

Box 1 Umbrella review evidence rating by strength of association Convincing Highly significant associations (P<10 −6 ) Cases of n >1000 I 2 <50% 95% prediction intervals excluding the null value Largest study nominally significant (P<0.05) No evidence of small study effects No evidence of excess significance bias Highly suggestive Highly significant associations (P<10 −6 ) Cases n >1000 Larg

All TLE + uMTS patients demonstrated ipsilateral hippocampal T2 more than two standard deviations greater than controls (mean: 135 ms, range: 122–160 ms); these differences were highly significant (Student's t test, p < 0.000001).

This analysis reveals a difference in the K A / K S distributions between intact copies and retropseudogenes (which may show low K A / K S ratios by chance), with a highly significant excess of intact copies for K A / K S < 0.5 ( Figure 2 ; p < 10 −6 , Fisher's exact test).

When all tumor samples were evaluated together the correlation of GZMH, ABL1, IL-7, LY9, IL-12, SCAMP3, and CD244 were highly significant ( p < 1 × 10 −6 ).

ANOVA with the main factor Age-Group (adults, children) and repeated measures factor Velocity (3 conditions) revealed a highly significant effect of Velocity on gamma power (F (2,122) = 172.8, ε = 0.87, p < 1e −6 ; η 2 = 0.74), but no effect for the Age-Group or the Age-Group*Velocity interaction (p’s > 0.6).

As shown in Figure 3 , while reduction in binding after treatment with unlabeled DARPin 9_29 was highly significant ( p < 0.000001), there was neither significant reduction in binding after receptor saturation using trastuzumab ( p > 0.05) nor any reduction in binding after treatment of SKOV-3 cells with cetuximab or bevacizumab.

The intra-correlations of IgE levels among newborn, 1.5, 3 and 6 years were highly significant correlated one another ( P <10 −6 ; Table 2 ).

In Supplementary Data 6 , the association of CHRM3 activation with “urinary contraction” (literature ID 364) contains the p value and ROC AUC for “Urinary retention” and is classified as highly significant ( p ≤ 1e-06), with distance 1 (i.e., the significant PT and starting PT are connected via 1 intermediate in the network, via the shared HT).

SwinIR and SeD fell below clinically acceptable thresholds, showing scores near 1.0 and highly significant differences across all categories ( P < .000001).

The likelihood ratio test was highly significant (χ 2 = 49.02, df = 10, p < 0.000001), as was the Wald test (χ 2 = 51.80, df = 10, p < 0.000001), indicating that the predictors collectively contributed meaningfully to HBV status classification.

A one-way repeated measures ANOVA confirms that the number of items had a highly significant effect on identification accuracy ( F (3,15) = 42.8, p <0.000001).

In all instances, the herd random effect was highly significant ( p < 10 −6 ), indicating a strong herd effect on the probability of Map shedding.

All disparities noted between the patient and control groups exhibited highly significant statistical significance for antibody titers against both antigens ( p < 10 −6 ) ( Table 5 ).

Finally, when correlation values were raised to c = -80% and c = +80% highly significant GC values were obtained (Figure 3A , c = -0.8, GC = 1.056, P < 1 × 10 -6 ; Figure 3E , c = 0.8, GC = 1.073, P < 1 × 10 -6 ).

By calculating the probability that 11 of 36 identified sites should fall in this binding region comprising 20 sites of a total 626 sites by chance ( Methods ), we found the concentration of sites identified as under positive selection in this region to be highly significant ( P < 10 −6 ).

Differences between eukaryotes and bacteria, or between eukaryotes and the combined archaeal/bacterial data set, were highly significant ( P < 10 -6 that both represent samples drawn from the same population for each pairwise test). 5.

A Kruskal-Wallis test showed a highly significant difference across groups ( H (2) = 2.9 × 10 5 , p < 10 −6 ).

The differences between MS and control findings was highly significant (p > 0.000001).

Our results show a highly significant difference in response to radiation damage between DAOY cells grown in adherent conditions and DAOY spheres (Fig. 4 ; Table 4 , p < 0.000001).

Significant differences were observed between the SIDS and non-SIDS groups: the presence of thymic petechiae in SIDS (89.5%) compared with non-SIDS (47.7%) was highly significant ( P < 0.000001; OR 9.38 (CL 4.5 to 19.9), and their absence was more frequent in non-SIDS (52.3%) compared with SIDS cases (10.4%) ( P < 0.000001).

Intrafamily K2P distances (F) were generally higher than congeneric (G) distances, which were definitely higher than intraspecific (S) distances ( Table 1 , all Mann-Whitney tests were highly significant, P value <10−6).

Compared to eleven published inactive conformation structures bound to various antagonists, the widening of the pocket by more than 2 Å caused by WAY-196619 is highly significant (Student’s t-test, p< 1×10 -6 )( Figure 4a ).