“highly significant”

The OR per standard deviation went from 1.75 to 1.44 as age increased from the 40s to 70s and that this trend was highly significant (p=3.44 × 10 −10 ) [ 152 ].

Linear regression analysis revealed a highly significant association between the number of siderophore loci carried by an isolate and its intracellular growth ( P = 3.51 × 10−10).

These two highly significant SNPs were rs1005277 near the ZNF25 gene (OR = 1.45, 95% CI, 1.29–1.62, p = 3.68 × 10 −10 ) and rs12417758 in a long non-coding RNA (lncRNA) gene, RP11-867G23.13 (OR = 1.22, 95% CI, 1.11–1.34, p = 3.66 × 10 −5 ).

We perform whole-exome or genome sequencing of 146 kindreds with sporadic (n = 138) or familial (n = 8) CFM, identifying a highly significant burden of loss of function variants in SF3B2 (P = 3.8 × 10 −10 ), a component of the U2 small nuclear ribonucleoprotein complex, in probands.

Furthermore, highly significant enrichments in biological functions have been observed to be related to the immune system; for example, inflammatory response ( P <3.84E10 −20 –1.53E10 −5 ), immunological disease ( P <8.93E10 −16 –1.65E10 −5 ), hematopoiesis ( P <3.09E10 −14 –4.98E10 −6 ) were frequently encountered.

However, linear regression analysis also demonstrated a highly significant overall correlation between cell loss and the vulnerability module scores (p-value = 3.89e-10), even when the input clusters were excluded from analysis ( Figure 6—figure supplement 1C ).

For the whole group of 253 students, the increase in net score means were 7.85% after SR, and 3.95% after CM; both were highly significant: P < 0.4 × 10 -9 for SR and P < 0.1 × 10 -3 for CM.

Finally, we found a highly significant overlap ( p = 4.08 e –10) of 20 DEGs between Mp spirrig and Atspirrig ( Supplementary Table S5 ).

As a result, and despite the limited number of points in the regression, we obtained a highly significant negative correlation ( P = 4.1 × 10 − 10 and R = −0.99), as in the example in Fig. 2d –f.

Yield strength represents the stress required to initiate plastic deformation and is a key indicator of a material’s load-bearing capacity. Statistical analysis ( Table S3b ) again confirmed a highly significant effect of processing method ( p = 4.10 × 10 –10 ), but no significant effect of HEC concentration ( p = 0.925).

Predictive value of the dichotomous score in risk subgroups When applying the cutoff defined in our previous study, PS29MRCdic was highly significant in the prediction of treatment failure (OR, 4.81; 95% CI, 2.95-7.93; P = 4.15 × 10 −10 ).

After this correction, residual SCC dissimilarity was still much higher for natural than for LL-synthetic stimuli and highly significant ( t test, P = 4.17e-10, t = 6.26, df = 7,468).

This enrichment was highly significant (OR, 227.55; 95% CI, 41.43–1,249.71; P = 4.23 × 10 –10 ).

We also performed a Mann–Whitney U -test between the results of the two models that were highly significant, U = 2587.5, n1 = n2 = 56, p = 4.3 × 10 −10 two-tailed, median of the sensor model = 0.77, and median of the baseline model = 0.64.

Similarly, hypomethylation in PD cases can be observed for two highly significant CpGs in immune-related genes cg04772575 in ABCB9 ( p = 4.3 × 10 –10 ) and cg11334709 in C1orf200 ( p = 7.5 × 10 –10 ).

This disproportion is highly significant statistically (χ 2 test, P = 4.4 × 10 −10 ).

6 d), with the TG association remaining highly significant even after adjustment for these metabolites (p = 4.4E−10).

This difference is highly significant ( P = 4.4 × 10 −10 in a one-tail z test).

GWAS Genome wide association analyses of IL-10 levels ( S3 Table ) resulted in one highly significant peak on chromosome 9 in the ACS patient cohort (top SNP: rs676457, P = 4.44*10 −10 ), and another borderline significant SNP on chromosome 6 in the healthy controls (rs11961593, P = 1.80 × 10 −7 ) ( Fig 1 ).

The other two highly significant markers 3173785|F|0–51:A > T-51:A > T on A09 ( -log 10(P) = 9.33) and 3105087|F|0–23:C > A-23:C > A on A09 associated with RE revealed normal monogenic segregation ratio ( χ2 : 4.08 to 4.38, P = 0.111 to 0.129) (Table S9 d).

The results suggested highly significant differences in KDM4A levels between normal mesothelial and MPM tissue specimens ( p = 4.74 × 10 –10 ).

In the families, we obtained a highly significant result for the pathway of eight genes for the quantitative trait Q1 ( p = 4.9 × 10 −10 ).

Repeated measure ANOVA demonstrated a highly significant effect of the group factor (good/bad learners: F 1;36 = 85.3, p = 4.9 × 10 −10 ) and the effect of the sex factor (male/female: F 1;36 = 64.4, p = 1.5 × 10 −9 ) on the reaction time.

Increases in the number of active licks across the test sessions was statistically highly significant [ F (1,19) = 133.5, p = 4.9 × 10 -10 ).

For peptides detected in both iTRAQ 4-plex as well as iTRAQ 8-plex labeled form, the median Mascot ions score was 53.9 for 4-plex and 45.6 for 8-plex, and a paired t test was highly significant at p < 5 × 10 −10 .