“highly significant”

One-way analysis of variance confirmed a highly significant difference in spore concentrations among all strains ( p = 2.36 × 10 –10 ; Supplementary Table 2 ).

A formal test of independence performed on the multi-way contingency table was highly significant (Chisq = 40.1, df = 1, p -value = 2.374e-10), revealing very strong associations between certain variables (Phi-Coefficient = 0.811), as graphically depicted in the association plot presented in Fig 6 .

Interestingly, we found a highly significant overlap between differentially expressed and alternatively transcribed genes in LPS response (63/150, hypergeometric test p < 2.4 × 10 −10 ), but no significant overlap between differentially expressed and alternatively transcribed genes between MDMs and IPSDMs (28/140, hypergeometric test p < 0.74).

Enrichment of the both GO categories was highly significant (cell cycle: p = 2.5E-10, immune system process: p = 0.00096).

This bias towards inactivation is highly significant (p = 2.5e-10 in a chi-squared test), indicating that more promoters are inactivated by E2 than are activated, which supports the previous report about estrogen-mediated early-down regulated genes [ 43 ].

The effect of test timing was highly significant ( F [1,28] = 91.42, η 2 = 0.77, p = 2.57 × 10 –10 ), indicating that participants scored higher on immediate recall than on delayed recall.

In the corresponding 2 × 2 analysis, the association between ≥2 organ involvement and systemic disease was highly significant ( p = 2.6 × 10 −10 ), with an effect size of OR 4.72 (95% CI 3.71–5.99).

At the iPSC stage, the most highly significant differentially expressed gene (DEG) was the NLRP2 inflammasome ( P =2.66 × 10 −10 ).

A highly significant ( P <2.664e −10 , two-sample test for equality of proportions) negative correlation ( R =−0.87, Pearson's product–momentum correlation) between Esrp2 KO and overexpression results indicates that developmentally regulated splicing of a subset of pre-mRNAs is extremely sensitive to ESRP2 levels ( Fig. 6f ).

demonstrated a highly significant, low-to-moderate correlation with BMI ( r = 0.249, p = 2.7 × 10 − 10 ).

We found a highly significant correlation between the number of GT n repeats in intron 2 of the TLR2 gene and the polymorphism Arg753Gln (rs5743708) (r = 0.0099038, P = 2.76 × 10 −10 ) (see S1 Fig ).

sentence under the heading “The genetic correlation between height and IQ: Shared genes or assortative mating?” in the Results section is incorrect and should read “We estimate that the additive genetic correlation between height and IQ is .13 in males and .22 in females , and these estimates were highly significant ( χ 2 (3) = 47.4, p = 2.8e-10).”

The log-rank test comparing the overall survival of the two groups was highly significant ( P ≤2.8E-10, Figure 2A ).

The difference between genders was highly significant ( p = 2.93 –10 ) i.e., men show higher blood Pb levels than women.

The Chi-square statistic was highly significant ( p = 2.93 × 10 −10 ), see Table 3 .

The test yielded a highly significant result ( p < 0.0000000003), which strongly suggests that this anatomical region is a low-yield zone for metastatic involvement in patients with intermediate- and high-risk PCa.

Strikingly, highly-biased genes constitute less than one-quarter of the X -linked genes, and this difference from the autosomal genes is highly significant (χ 2 test, P = 3 × 10 -10 ) (Figure 3 , orange bars).

When cells at metaphase and anaphase were pooled, the difference in θ remained highly significant (p = 3.018e-10) ( Figure 2 D, E15.5).

When the endospores were pre‐treated with unconjugated WGA followed by probing them with Anti‐PpWS, there was a highly significant decrease based on CTCF values ( p = 3.09e −10 ; (Schindelin et al., 2012 ) in the recognition of the antibody (Figure 7C ).

The combined influence of tissue and cell type (ie, SI crypts, SI mucosa, and so forth) were also a highly significant predictor of DNA methylation age ( P < 3.1 × 10 -10 ).

This model was found to be highly significant (ANOVA CV p = 3.1 E -10 ) and no regional influence could be discerned.

Comparing pre- and post-treatment conditions, Student’s t -test demonstrated a highly significant difference ( p = 3.13 × 10 −10 ), strongly supporting the hypothesis of treatment-related improvement.

The CMT-GWAS (multitrait) method resulted in more highly significant peaks and a lower FDR than any of the single-trait GWAS (FDR < 0.01; P < 3.2 × 10 −10 ) (Fig. 3 ).

This enrichment is highly significant (hypergeometric test followed by Benjamini–Hochberg FDR correction 33 : expected 7.5 TK, observed 24 TK, p = 3.2 × 10 -10 , FDR-corrected q = 1.9 × 10 -9 ).

The first, on chromosome 16, had a highly significant association (log p = 9.48) and lies in an intron of a cell adhesion molecule, Lsamp (limbic system-associated membrane protein), whose deletion is known to alter behavior in the EPM. 68 , 69 We found a significant interaction ( p = 0.001; Table 1 ), indicating that the effect of the QTL is mediated by the Lsamp gene.