First, they represent a consistent and highly significant (Wilcoxon test P < 10 −15 in all growth phases except LS) decrease in expression across hundreds of rpoS regulated genes, in all five growth phases.
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Again, we found a highly significant overlap (Fig. 2 b), with 43.1% (401/931, p < 1.0 × 10 −15 ) of the HIV-responsive proteins identified here being part of the HHPID.
1d ) fitted the standard logistic population growth model well and displayed highly significant increase in biomass ( p < 10 –15 , likelihood ratio test), which is typical for the growth of microorganisms under favorable conditions 23 .
picta as indicated by the highly significant logistic regression of male proportion against wCTUs (Z = −15.15, P < 1 × 10 −15 ) (Fig. 3c ).
The association between C/EBP δ mRNA expression and sensitivity to panobinostat is replicated in LC 2 from CTRPv2, with the pairwise relationship also being highly significant (Spearman ρ = −0.30, p < 1 × 10 −15 ).
Analyzing the AMΦ data with linear models to control for batch effects, we found a highly significant effect of CSE concentration (p < 10 −15 ) on phagocytosis.
Figure 2b shows the correlation between image memorability and IT population response magnitudes, which was strong and highly significant (Pearson correlation: r = 0.68; p=1×10 −15 ).
We have to reject the null hypothesis and this result is highly significant ( p < 10 −15 ).
The differences in median PEN MICs were highly significant ( P < 1 × 10 −15 for all pair-wise comparisons by Mann-Whitney U test).
Stepwise analysis of the multivariate model resulted in a highly significant ( F 11,1571 = 16.86, P < 10 −15 ) equation with eight additive directional terms (LINE, R.CALL, R.VOL, R.CHIRP, R.V.PULSE/CHIRP, R.V.CHIRP.W, R.IPULSE.W), one stabilizing term (PULSE, labeled as S.PULSE in the equation) and three interactions (LINExR.VOL, LINExR.CHIRP, LINExR.IPULSE.W).
4 ), and this difference is highly significant (Wilcoxon rank-sum test, P < 10 − 15 ).
We also plotted the USP51 protein score versus the DGCR8 protein score for individual patients, which revealed a highly significant correlation (Pearson R 2 = 0.52, P < 1 × 10 −15 ; Supplementary Fig. 7c ), indicating the relevance of the identified regulatory mechanism in human cancer.
The resulting clusters were a highly significant predictor of MIC ( p < 10 −15 ; Table 1 (A)) showing that genomically similar isolates tend to have similar MIC values.
Kruskal–Wallis H tests on statistical differences in the distributions between the baseline model and the full model are highly significant ( P < 1 e −15 ).
Comparing between a paper’s date of publication and its citation count reveals there is a low anti-correlation (−0.2) but highly significant between the two (Pearson product-moment correlation test P -value < 10 −15 , Supplementary Fig.
Highly significant linkage disequilibrium was found between the cream locus and SNP8 (LRT = 88.5, P < 10-15 ), SNP1 (LRT = 41.6, P < 10-10 ) and Del (LRT = 32.5, P < 10-8 ).
We observe a 8% depletion of fragile codons in single-exon genes that is highly significant ( p <10 −15 , Wilcoxon rank sum test; Table 1 ).
This test was highly significant for all four types (charge, volume, polarity and Grantham distance) of coevolving groups ( p -values < 10 -15 ).
Analysing the combined amino acid composition of the complete proteomes, we indeed find a small but statistically highly significant shift in ERK of endothermic compared to ectothermic vertebrates (Figure 3 ; Wilcoxon rank sum test: p < 10 -15 ).
This enrichment of accelerated blocks near duplicated genes is highly significant (FET: P < 1 × 10 −15 , OR = 8.41 [95% CI, 7.18–9.82]; see row one in table 3 ).
Application to the present data indicated that TT has a very highly significant effect on hit rate (p < 10 -15 ), as shown in Table 1 .
Quantification of glial nuclear basket ::GFP levels normalized to the oil vehicle control (1.0 ± 0.029, n = 13; 10 nuclei averaged per data point) shows a highly significant ~ 200% mean nuclear elevation following critical period EB experience (1.904 ± 0.030, n = 17; t (28) = 21.24, p < 1.0 × 10 −15 , two-tailed unpaired t- test; Fig. 5 B).
Likewise, it is intriguing that there is a highly significant overlap (p < 10E −16 , Fisher’s exact test) between the transcripts identified as PTZ stimulated, particularly those that are downregulated, and those described previously as bound to astrocyte ribosomes in perisynaptic fractions ( Sakers et al., 2017 ).
Our analysis of first round data indicates that while there was considerable diversity in the raw scores provided by individual participants, the inter-rater concordance was substantial and statistically highly significant (Kendall’s W=0.150, p-value < 10 −15 ).
We find a highly significant negative correlation between the two measures (linear regression: R 2 =0.34, P <10 –15 ), which is illustrated in Fig. 4 .