However CLIC1 −/− mice immunised with MOG 1-125 -pulsed CLIC1 −/− BMDCs compared to CLIC1 +/+ BMDCs, in the disease development phase, displayed less severe EAE disease that fell just short of statistical significance ( Fig. 8 C; n =6/group; P =0.064, two-way repeated-measures ANOVA).
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And the correlation with ESR remained significant even when a sample with uniquely high Treg numbers was excluded (r = −0.358, p = 0.008) (Additional file 1 : Figure S3A), while the correlation with DAS28 scores fell just short of statistical significance (r = −0.256, p = 0.064) (Additional file 1 : Figure S3B).
In the same study, there was a reduced rate of secondary adhesive capsulitis at 6-months in the TXA group versus placebo, although this association fell just short of statistical significance ( p = .066).
An additional network meta‐analysis, conducted to account for the repeated use of the same control group in multi‐arm studies, revealed that mixed training yielded the largest effect (MD = +1.20 kg, 95% CI: +0.67, +1.73 kg; p < 0.001, P‐score = 0.93), followed by strength training (MD = +0.83 kg, 95% CI: +0.17, +1.49; p = 0.013; P‐score = 0.66), while endurance training fell just short of statistical significance (MD = +0.51 kg, 95% CI: −0.04, +1.05; p = 0.067; P‐score = 0.41).
In fully adjusted models, the percentage of White, Black, and Hispanic residents remained positive and significant predictors of permissive surrogacy laws, while religiosity trended negative but fell just short of statistical significance (p = 0.07).
There was a trend for an increase in the number of CD4 T cells/g of tumor, but this fell just short of statistical significance ( Table 1 , p = 0.07).
a positive trendgold
On symptoms, the Phase 2 showed a positive trend: dysphagia symptom scores improved more in the 360 mg cendakimab group than placebo, but the difference fell just short of statistical significance at 16 weeks ( p = 0.073) [ 89 ].
A similar overall pattern was seen in dispersion over the 18-month extended disease progression analysis; there was numeric improvement over time that fell just short of statistical significance ( p = 0.073), but the overall rates of change across time did not differ by group ( p = 0.993).
a weak trendgold
APDQ Multiple regression analysis of overall scores showed a weak trend towards lower scores in assessment of attitudes towards patients with a previous diagnosis of BPD compared with patients with a previous diagnosis of depression (lower scores indicate more negative attitudes in the APDQ and this is consistent with findings from the Appleby measure); however, this difference fell just short of statistical significance ( z = 1.75, P = 0.08).
Although the interaction fell just short of statistical significance ( P = 0.08), the correlation between adiponectin and insulin resistance appeared to be stronger when physical activity levels were lower ( r = −0.21 physical activity < median versus r = +0.08 for physical activity > median).
In this analysis of five Asian populations, BMI fell just short of statistical significance ( P = 0.0831), which suggests that there might be a possible effect of BMI on treatment outcome (beta risk).
CMJ and peak power demonstrated moderate positive effects (estimates of 0.90 and 0.87 respectively), though these fell just short of statistical significance (p = 0.096 and p = 0.051).
The 24 IU dose of oxytocin attenuated cortisol levels relative to placebo [ F (1,16)=4.496, p =0.05, partial η 2 =0.22) and the 48 IU dose, although the latter fell just short of statistical significance [ F (1,16)=3.054, p =0.10, partial η 2 =0.16).
The cancer rate was higher in US high risk nodules (48.7 versus 29.9% in low-risk US nodules) but this difference fell just short of statistical significance ( p = 0.10), probably due to the small cohort of indeterminate thyroid nodules submitted to surgery.
Also, whereas child blood Hg levels fell just short of statistical significance (b = -0.11, p = 0.10), cord and adolescent blood Hg levels (b = -0.22, p = 0.001; b = -0.14, p = 0.04), were significantly associated with lower BSSS-4 total scores.
As shown in Figure 8A,B , even though the tumors grown in the ZOE‐treated mice after 6 weeks fell just short of statistical significance ( p = 0.114), the tumors after 4 or 5 weeks were significantly smaller than those grown in the control group ( p = 0.029).
The difference between the two groups in terms of the number of times the mice entered the open arms fell just short of statistical significance (7.000 ± 0.8498 vs . 9.800 ± 1.685, P = 0.1213).
Plasma FGF23 levels were noted to be highest in group 4 and lowest in group 1, suggesting a potential effect of PHEX genotype on XLH disease severity, but this trend fell just short of statistical significance ( P = .13).
A correlation of quality of life and sleep quality fell just short of statistical significance ( p = 0.28).
In addition, NP+ve disease was more strongly related to diabetes (OR 1.6) and work with vibratory tools (OR 1.4), although the differences fell just short of statistical significance.
Finally, appearing before the college's PCC (OR=4.21, p= 0.056) fell just short of statistical significance.
The area under the curve of the glucose tolerance test was decreased in the high fat-fed MIC-1/GDF15 transgenic mice compared to corresponding control mice, but this fell just short of statistical significance ( Fig. 4B ).
We reiterate again that the effects seen fell just short of statistical significance.
Intake of grains and calories did not increase significantly at mid-intervention in the intervention group although the snacks were all grain-based and the increased consumption in grains fell just short of statistical significance.
Comparisons between US2-Syr (which experienced the most mortality (about 35% at 60 days)) and US1-PA as well as between US1-NJ and US1-MD fell just short of statistical significance ( Table 4 ).