“failed to reach statistical significance”

5 , 17 As expected based on published literature, 18 controls had a higher number of species than cases, although saliva species failed to reach statistical significance (151 and 38 species identified in plasma, Chi square X 2 = 29.473, p = 5.671e-08; 145 and 64 species found in serum, Chi square X 2 = 15.338, p = 8.988e-05; 90 and 44 species found in saliva, Chi square X 2 = 1.6647e-27, p = 1).

For some of these cancers, increased risk was observed in our study, but failed to reach statistical significance after the Bonferroni correction for 53 tests ( p < 1E‐04), including stomach (HR = 2.10, p = 0.03), esophagus (HR = 2.07, p = 0.02), and uterine cancer (HR = 1.69, p = 0.05).

While CBL0137 and gemcitabine monotherapy had only a modest effect on PANC-1 orthotopic tumor growth, which failed to reach statistical significance (39% and 20% growth inhibition, respectively), the combination of the two agents caused a substantial decrease in PANC-1 tumor growth (78% growth inhibition, P=0.0002; Fig. 2A ).

When ANOVA of V T with group (patients with CNI therapy versus controls) and VOI as fixed factors was performed separately for HAB and MAB subjects, the group effect (lower V T in patients with CNI therapy) was highly significant in the HAB subjects ( p < 0.0005), but it failed to reach statistical significance in the MAB subjects ( p = 0.106).

Indeed, with the D 2 O method, milk production was 34% lower in LP dams, compared with control dams (P = 0.016) whereas the difference failed to reach statistical significance with the WSW method, except at PND 14 (P = 0.0008) during the peak of lactation.

Initial active hole responding was lower in mice infused with Homer2b-cDNA into the NAC shell than that typically observed under our oral MA operant-conditioning procedures ( Figure 6D ) and the Genotype X Day interaction failed to reach statistical significance [Day effect: F(4,128) = 4.79, p = 0.001; Genotype X Day, p = 0.095].

However, while the effect on pericardial adipose tissue mass after endurance training failed to reach statistical significance, resistance training significantly reduced pericardial adipose tissue mass by 31% ( p < 0.001).

Particularly, albeit the overall INTERVENTION × TIME interaction (Wilks’ λ = 0.875, F 18,583.141 = 1.572, p = 0.062) failed to reach statistical significance, an INTERVENTION × TIME interaction on IAR inter-subject difference was significant ( F 6,208 = 4.270, p < 0.001).

This moderation effect was observed in women (£52–100 k per year: β = 0.086, 95%CI [0.073 to 0.100]; <£18 k: β = 0.111, 95%CI [0.098 to 0.123], p = 0.002) and not men (β = 0.054, 95%CI [0.044 to 0.064] vs β = 0.059, 95%CI [0.047 to 0.070], p = 0.006), although the sex difference failed to reach statistical significance in a three-way interaction term corrected for multiple testing (p = 0.001).

Although differences in clinician rated clinical improvement between the groups failed to reach statistical significance, patients in the intervention group had more favourable subjective quality of life ratings (β=0.71, 95% confidence interval 0.26 to 1.15, P=0.002).

While on a per-study level, this analysis failed to reach statistical significance, but for the proportion of ATTRv patients in ATTRACT, among the three trials, a highly significant tendency towards a higher proportion of male ( p = 0.003) and ATTRv ( p = 0.016) participants and was observed.

Although the primary endpoint of 1-year OS rate failed to reach statistical significance, a post-hoc analysis revealed that the 2-year OS rate was significantly increased in the TRT group (13% vs. 3%, P = 0.004) ( 3 ).

Although a slight increase in spectral slope was observed under cathodal so-tDCS relative to sham, this change failed to reach statistical significance ( F (2, 42) = 6.121, p = 0.005, partial η 2 = 0.226; planed contrast cathodal vs. sham: p -adj = 0.073; Cohen’s d = 0.402).

Although individual differences generally failed to reach statistical significance for genes other than R10 (Table 2 ), these distributions of differences for LGR and LP (χ 2 = 8.0, P = 0.005) as well as for SD (χ 2 = 2.0, P = 0.10), are unlikely to be due to chance only.

Including patients receiving rhPTH therapy, a lower serum phosphate concentration (odds ratio 1.364 [95% confidence interval (CI) 1.049-1.776], p<0.05) and a longer disease duration of HPT (odds ratio 1.063 [95% CI 1.021-1.106], p<0.01) were significant predictors for renal calcifications, whereas 24-hour urinary calcium excretion was elevated in patients with renal calcifications but failed to reach statistical significance (odds ratio 1.137 95% CI 0.999-1.294, p=0.0053]) ( Table S3 ).

While greater restrictions generally slowed viral transmission, they failed to reach statistical significance and reduced GDP ( p = 0.006).

Sensitivity analysis revealed no differences, and only mean absolute DBP failed to reach statistical significance ( F [1,371] = 7.50, p = 0.006), unlike in the full sample.

We also observed a time x condition interaction effect on action planning, F (1,252) = 4.22, p = .041, η p 2 = 0.016; however, it failed to reach statistical significance at the p < .01 level.

Levosimendan was associated with a higher incidence of hypotension than dobutamine, although it failed to reach statistical significance (SMD: − 0.33; CI [−0.58, − 0.08]; P = 0.010) with an insignificant amount of heterogeneity (I 2 = 1%; P = 0.31) (Supplemental Digital Content Figure 18, available at: http://links.lww.com/MS9/B74 ).

In contrast, patients with ventricular arrhythmias had a higher proportion of patients with LVH and left ventricular dysfunction, but the difference failed to reach statistical significance. 16 Genovesi et al . noted that patients with AF were older (71.8 vs 64.7, p < 0.01), and its prevalence increased with age. 21 Also, AF was associated significantly with IHD, dilated cardiomyopathy, acute pulmonary edema, valvular disease, cerebrovascular accidents, and predialysis hyperkalemia. 21 Patients with AF more frequently showed left atrial dilatation, and LVEF was significantly lower.

Although results for the Teeth exam, Handling test, and Stranger test showed a similar pattern, the effect of level of behavior on length of stay failed to reach statistical significance at the p ≤ 0.01 level ( Table 4 and Table 6 ).

In addition, heavy cannabis users had higher monocyte count, yet the association failed to reach statistical significance at the adjusted p < 0.01.

Six weeks after depletion, both ILC numbers and ILC3 proliferation trended upwards, but differences failed to reach statistical significance ( Figure 6b-c ), while the percentage of ILC3 cells expressing MHCII fell by one third (P=0.014) ( Figure 6d ).

For bite force endurance, all comparisons of distributional differences failed to reach statistical significance at a level of p < 0.017 Bonferroni corrected (all z ≤ 1.899).

In the minimally adjusted model, children with high SCDC scores had higher odds of making errors in the recognition of angry faces (OR = 1.5, 95% CI = 1.1, 2.0; p = .0004); however, in the fully adjusted model, this difference failed to reach statistical significance after adjusting for multiple comparisons (OR =1.5, 95% CI = 1.1, 2.1; p = .02).