Barely Significant
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“extremely significant”

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extremely significantp < 0.010.2× alphaqualified
A Duncan’s multiple-range test was employed to compare the control and other treatment groups; a significant difference was observed when p < 0.05 and present with *, and an extremely significant difference was observed when p < 0.01 present with **.
extremely significantP < 0.010.2× alphaqualified
Two benzothiophene and L-(+)-valine, ethyl mercury ions were extremely significant positive correlation ( P < 0.01), aminomethyl phosphonic acid and ethyl mercury ions were significantly negative correlation ( P < 0.05), sucrose and 6-hydroxy-1,2-adipic acid dioctyl ester, misha ossification alcohol, 2-ammonia-4-oxygen generation butyrate were extremely significant positive correlation ( P < 0.01), and (3R, 4S, 9R, 11R)-27-(4-hydroxy phenyl)-4-methyl-3,9,11-seven alkoxy three alcohol has significant negative correlation ( P < 0.05; Tables 2 – 4 ).
extremely significantP < 0.010.2× alphaqualified
We examined a total of 60 cows, including subclinical laminitis, chronic laminitis and healthy without any symptoms with 20 animals in each group. Inflammatory mediators Compared with healthy cows, HIS, IL-6, LPS, and TNF-α in subclinical laminitis group significantly increased ( P < 0.05), extremely significant increased HIS, LPS, TNF-α ( P < 0.01) as shown in (Figs. 1 , 2 , 3 , 4 , 5 ); compared with healthy cows, COX-2, HIS, IL-6, LPS, and TNF-α in chronic laminitis cows were significantly increased ( P < 0.05), extremely significant increased COX-2, HIS, TNF-α ( P < 0.01) as shown in (Figs. 1 , 2 , 3 , 4 , 5 ).