In line, the same trend was observed for IHC‐based protein expression of the seven markers in the validation cohort, although it did not quite reach statistical significance when tested as a negative survival predictor (HR (high) = 2.68 [0.88–8.14], P (HR) = 0.082) (Fig.
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Consistent with the UCSF results, when all three NFκB and AP-1 upregulated genes were combined to produce four subsets within each dataset, the resulting Kaplan-Meier curves showed a rank order correlation between increasingly worse outcome and number of high expressing genes (HHH > HHL > HLL > LLL); although these outcome differences did not quite reach statistical significance by Log Rank analysis, in each dataset those cases showing high expression of all three NFκB and AP-1 upregulated genes (HHH) exhibited median times to metastatic recurrence ≤ 5 years (data not shown).
In addition, 16‐month‐old WT mice had a tendency to have a higher SREBP1 mRNA level than younger counterparts, but this did not quite reach statistical significance.
TMR/PRP patients had an increased mean EF compared to CABG alone (57.8% vs 54.1%, p = 0.24, Figure 5 ), though this did not quite reach statistical significance.
There was a larger rate of false non‐remissions predictions in women for the FEP model, although this did not quite reach statistical significance: the differences in model performance may therefore also be due to increased response rates in women, which is consistent with current literature, 52 leading to an unexpected better outcome.
This study showed that African-American lupus patients may be less likely than their white lupus counterparts to participate in a clinical research trial, although this difference did not quite reach statistical significance.
Although these differences did not quite reach statistical significance due to the small numbers, they suggest that docetaxel resistance is twice as likely in TMPRSS2 ERG-positive CRPC than in TMPRSS2 ERG-negative prostate cancers.
However, unlike the estimates for non-SNAP users presented above, these were much attenuated effects and the differences did not quite reach statistical significance.
The pathway from member Z’s pre-collaborative preferences to member Y’s post-collaborative preferences did not quite reach statistical significance based on the bias-corrected confidence interval including zero ( B = 0.13 [− 0.015, 0.388]).
However, when the age restriction was not applied (ie, allowing persons younger than 65 years of age to be included), the analysis produced a pooled ratio of 0.86 (95% CI 0.73 to 1.01) and, thus, did not quite reach statistical significance.
Cardiac growth and gene expression The transient growth restriction was also reflected in a tendency ( P = 0.07) for the heart weights of the DEX fetuses to be lower at E14.5; this did not quite reach statistical significance probably due to the inaccuracies in weighing hearts of such small size.
20 This result did not quite reach statistical significance, probably because of a lack of study power for this outcome; however, it represents almost a 30% reduction in the expulsive phase of labor.
Although the difference did not quite reach statistical significance, this study may indicate a higher injury risk on artificial turf than on natural grass in forward position.
In the present study, women living on their own reported less loneliness than women living with someone, although the comparison did not quite reach statistical significance.
[6] , [7] , [8] Therefore, the statistical power of this analysis is small and the primary endpoint, TVR, did not quite reach statistical significance.
AKR/J mice, which showed a high increase of other disease parameters, had high strain scores, but did not quite reach statistical significance ( Fig. 1 ). 3.2 Histology Histological sections were examined and scored according to Spormann ( Fig. 2 ) [2] , [8] .
Although the primary outcome, death or major disability, did not quite reach statistical significance favoring the intensive treatment group, secondary endpoints such as functional recovery based on an ordinal analysis and quality of life did [ 18 ].
The median right ventricular pressure as a percentage of left ventricular pressure (RVP/LVP ratio) and the median PVR were distinctly lower in those with PH due to BPD compared to those with IPH, but the differences did not quite reach statistical significance.
That said, although for bands in the 32 and 68 kDa (clusters 4 and 6) a number of AEBSF-sensitive labelled bands appeared to differ between the CD and UC-derived samples, the difference in the activity index did not quite reach statistical significance (Fig. 3C ).
Whereas MNs expressing inhPSAM showed an increased burden of LC3A and misfSOD1 accumulation (although the latter did not quite reach statistical significance in the present work) compared with noninfected MNs ( Saxena et al., 2013 ), MNs expressing D(Gs) displayed a reduced load of both disease markers ( Fig. 6, D and E ).
All RUPP rats had an increase in percent reabsorptions and decrease in percent survival, despite the IL-2 dose administered ( p < 0.05) (Table 1 ), with RUPP + MD ( p = 0.43) and RUPP + HD IL-2 ( p = 0.33) increasing fetal death to a much greater degree than RUPP alone; however, this did not quite reach statistical significance.
Nevertheless, it did not quite reach statistical significance or improve the model AIC and was therefore excluded from the final model (Table 1 ).
The tumors treated with 1 μg PrAg-PCIS toxin also showed reduced staining and loss of viability, which did not quite reach statistical significance relative to the vehicle treated control group (Figures 8A, 8E ).
The risk of DVT was 4 times greater in patients treated without prophylaxis; however, this did not quite reach statistical significance in our conservative analysis ( Table 10 ).
We found that adding ascorbate (100 μmol/L) to the lower compartment further enhanced fMLP-stimulated directional motility of the cells, although this did not quite reach statistical significance ( Figure 3 ). 3.3.