did not quite reach significancep = 0.051
When TMB score was added to the adjusted variables above, the 2tPD-L1 more accurately could predict survival; however, this, too, did not quite reach significance ( p = 0.051) ( Table 4 ). 3.6.
When TMB score was added to the adjusted variables above, the 2tPD-L1 more accurately could predict survival; however, this, too, did not quite reach significance ( p = 0.051) ( Table 4 ). 3.6.
The BCG vaccinated males also had an increase in IL-2 to CA at V2, which did not quite reach significance ( p = 0.0512), but declined significantly by V3 (V2 vs V3 p = 0.0498) (Figure 3 E).
We saw a trend for increased cytoplasmic wild-type FUS in FUSDelta14 motor neurons but this did not quite reach significance ( P = 0.0512).
Two-way ANOVA revealed a strong trend for genotype differences in Wake that did not quite reach significance ( p = 0.0512) and significant genotype (F (1, 18) = 7.719, p = 0.0124) and time x genotype (F (23, 414) = 1.857, p = 0.0099) differences for REM sleep.
Pre-treatment with T increased IL8 production in response to MDP, which was reduced by TC and TCN but did not quite reach significance (Friedman test p = 0.0517, figure 6B ).
HSV-2 neutralization In Segment A, all CVL samples collected 24 hours after insertion of a single film exhibited 100% neutralization of HSV-2; however, the omnibus F test p -value for the ANOVA for HSV-2 neutralization did not quite reach significance ( p = 0.052) due to small sample size and neutralization activity in some of the baseline samples ( Fig 5B and S4 Fig ).
This apparent shift did not quite reach significance (Additional file 1 : Fig S1. midpoint of inactivation, p = 0.052; n.t. control −67.7 ± 2.4 mV, n = 18; β4siRNA −73.6 ± 2.6 mV, n = 20).
Cu also trended higher in the deep samples but did not quite reach significance ( p = 0.052).
As above, the main effects of Format match, F (1, 34) = 89.2, p < .001, and of Congruency, F (1, 34) = 51.3, p < .001, were significant, although the Format match × Congruency interaction did not quite reach significance, F (1, 34) = 4.06, p = .052 (although it was in the same direction as above).
In terms of the relationships between different outcomes, there are significant correlations between improvements in positive symptoms and a worsening in hopelessness ( R = −0.978, P = .022, N = 4), improvements in negative symptoms ( R = 0.830, P < .001, N = 23), and some evidence of improved functioning, but this did not quite reach significance ( R = 0.510, P = .052, 2 tailed, N = 15).
Unfortunately, in our original experiment, this difference did not quite reach significance in isolation (p = 0.053).
The ACL-RSI score was higher for the pediatric group compared to the adult group but did not quite reach significance (82% vs 77%, p = 0.053).
At the end of hypoxia, therefore, Ang II levels were still higher in untreated preterm animals compared with term animals ( P = 0.007) and the mean level in glucocorticoid‐exposed preterm piglets was lower than in untreated preterm animals, although this did not quite reach significance ( P = 0.053).
There was a suggestion that females were less likely to be category A recorders but this did not quite reach significance (Fisher exact test P = 0.053).
Reduction in perceptions of potential damage to relationships with patients did not quite reach significance [F (1,226) = 3.77, p = 0.054].
The Tspyl2 KO mice were marginally more active than WT controls, though this difference did not quite reach significance [ F (1, 78) = 4.13, p = 0.054].
Post-mortem Macroscopic Score There was an improved (lower) total macroscopic OA joint score in sheep that had received hUC-MSCs (11 ± 4) compared with the no cell control group (14 ± 6), but this did not quite reach significance ( P = 0.054; Fig. 3A ; Table S1 ).
The amyloid‐PGS was also significantly associated with A+ (OR = 0.492, P = 0.026), whereas the ptau‐PGS did not quite reach significance (OR = 3.218, P = 0.054).
In a tri-variate analysis with all three parameters, the influence of pAkt-IR did not quite reach significance (P = 0.054, Table 4 ).
However, this comparison did not quite reach significance in a non-parametric t -test ( U = 19, p = 0.054).
The amyloid‐PGS was also significantly associated with A+ (OR = 0.492, P = 0.026), whereas the ptau‐PGS did not quite reach significance (OR = 3.218, P = 0.054).
For cortical slices treated at ZT12, Student’s t-test indicated that there was a difference in the percentage of Grade 3 cells that did not quite reach significance ( p =0.0541) between control vs.
A similar trend was observed for τ 2 , but this did not quite reach significance (P = 0.055, t = 2.378, df = 6; One Sample T-test).
Although this difference did not quite reach significance (p=0.055), collectively the results indicate that T cell-dependent antibodies contribute to the overall protection induced against GAS-M1 following immunization with GAS-2W.M1. 3.3 The 2W Th cell epitope promotes an enhanced CD4 T cell IFN-γ response in GAS-2W.M1-immunized mice Children are more susceptible to superficial GAS infections than adults and this correlates with reduced IgG3 and IFN-γ production ( 20 ).
There was also a significant effect of MW181 on IL-6 levels in LPS-treated WT mice (F (2, 47) = 5,808; p = 0.0056); again, 20 mg/kg of MW181 inhibited IL-6 levels ( p = 0.0071), but the inhibition by MW181 at 5 mg/kg did not quite reach significance ( p = 0.055).