In hippocampus, KYN, 3-HK levels were also significantly higher than MRL, with increases in 3-HAA and QA close to significance.
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“close to significance”
In the literature
The greater psychological openness for psychological help in the more youthful generation was confirmed in our study at a level close to significance.
The absence of significant variation in the ratio CHOL/HDL between EW and LW (although close to significance) and the maintenance of this ratio at a low level throughout winter [ 60 ] leads to the conclusion that the proportion of so-called “bad cholesterol” (LDL) might remain stable and low.
In multivariable analysis, skin color association with Hb Z score was no more significant but there was a relationship with area of origin, age at arrival, MCV, and the relationship with presence of parasites was close to significance (see Table 2 , Fig. 3 ).
Five genes showed similar transcript levels among the four experimental groups: BAX , CIRBP , NLRP5 , OCT4 , and STAR , while FSHR showed a difference close to significance between controls and the three treated groups ( Figure 4 ).
In group3 obese individuals had lower ghrelin levels than normal weight subjects, this issue also was observed in diabetic patients with P: 0.07, which is close to significance and appears to be significant in higher sample sizes.
Of note, however, the p -value originating from the comparison of symptoms between groups was close to significance for the frequency of asymptomatic and pauci-symptomatic individuals in the vaccinated groups compared to the non-vaccinated one, as expected.
IL-6 and IL-8 levels in blood decreased after smoking in healthy controls, a change that was close to significance when compared with the change in COPD patients.
However, all other pairwise comparisons were either significant or close to significance.
4 a, b illustrate cytokines/chemokines that are close to significance, but may show clinically relevant effect size.
No significant effect of the supplementation on salivary metanephrine itself was observed; however, it was close to significance level.
Further work will be required to validate our TREM2 findings, particularly those close to significance thresholds (i.e. interactions with sex and APOE -ε4).
Our relatively small sample size reduced the statistical power of secondary analyses; it would be interesting to see the effects of a larger sample on our results, especially in comparisons that came close to significance.
The comparison between the frequency of genotypes for the TLR7 rs179008 A/T polymorphism between the control and HTLV-1 groups did not show significant differences according to sex, although the frequency of the polymorphic allele (T) was greater in females in the HTLV-1 group, with a p value close to significance.
As a result, the significant group difference at T0‐T1 according to covariate adjustment and at T0‐T2 according to change are no longer significant, although the latter is still close to significance.
Changes in leptin and PAI-1 levels were reported at 12 months, with a 6-month P -value close to significance in the case of PAI-1.
35 Differences close to significance existed in aspects such as educational level, where one of the centers had a greater number of patients with university degrees, which could justify the lower HRQL of patients from the HUGC. 36 , 37 Despite the homogeneity of the inclusion criteria of both centers, patients had a higher degree of dyspnea, expectoration, wheezing, daytime drowsiness, fever, edema, the need to sleep in a sitting position, the pain, number of comorbidities, anxiety, depression, and dependence in the performance of daily activities in the HUGC versus the HCB.
However, the result of multivariate Cox regression was only close to significance in the Caucasian LUAD patients (Table 3 ).
Among females, morning vaccination resulted in a greater antibody response to the A/H1N1 strain and was close to significance for the B strain.
73 A meta-analysis of the few six prospective cohort studies in women showed no overall association between total milk intake and hip fracture risk, only in the three studies in men the pooled RR per daily glass of milk was 0.91 (close to significance with 95% confidence interval 0.81–1.01). 15 However, being aware of the differences in the quality of nutritional assessments, the result of this analysis has to be taken with caution.
The results were close to significance and in agreement with previous reports indicating that Neospora seropositivity can be very stable through time and infected cows can show a variable rate of repeat abortions. 19 Also, cows with a history of previous abortion were more likely to abort than cows with no prior history of abortion. 20 Hence, culling of seropositive animals with one abortion could be considered as an option for limiting the economic losses due to this parasitic infection.
NEWS was the only score which reached statistical significance regardless the aetiology ( p = 0.030 for respiratory, p = 0.036 for urinary, p = 0.044 for abdominal, p = 0.047 for miscellaneous and p = 0.041 for indeterminate infections) although MqSOFA, lactate assay and qSOFA were close to significance.
coli , and was close to significance for S. choleraesuis .
The CRL/placental volume ratio was positively associated with the nutritional score, with a p -value close to significance after full adjustment.
This low prevalence also explains why the accuracy of the Random Forest analysis was not significant (although close to significance).