Barely Significant
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“close to significance”

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close to significancep = 0.0541.1× alpha
In contrast, mortality was significantly decreased by cetuximab treatment in univariate analysis (HR: 0.228, 95% CI: 0.054–0.968, p = 0.045) and was decreased with close to significance in multivariate analysis (HR: 0.233, 95% CI: 0.053–1.028, p = 0.054) (Table 3 ).
close to significanceP = 0·0541.1× alpha
Women who reported consuming at least two portions of seafood (white fish, oily fish or other seafood) per week had a significantly higher concentration of Se in both whole blood and toenails ( P = 0·001 for each); the significance disappeared after adjustment, but remained close to significance for whole-blood Se concentration ( P = 0·054).
close to significancep = 0.0541.1× alpha
When the RTPJ region for the first split was tested with the second split samples, the RRS association was significant (t[107] = 2.156, p = 0.033), and when the RTPJ region for the second split was tested with the first split samples, the RRS association was close to significance (t[106] = 1.952, p = 0.054).
close to significanceP = 0.0541.1× alpha
In contrast, the rate of progression in the nonsurgical group (13.2% and 17.1% in the non-matched and matched nonsurgical groups, respectively) was comparable to rates seen in our previous observational studies 20 , 22 The difference in the proportion of patients with progression to DCM was close to significance ( P = 0.054) compared to our non-matched non-surgical group.
close to significanceP = 0.0541.1× alpha
without bacteremia ( P > 0.4 for all, data not shown). var transcript levels and associations with parasite biomass, sequestered parasite load, or endothelial activation in severe malaria In all children with severe malaria (children with CM, SMA, or CM/SMA), there was no correlation of transcript levels of any var gene group with parasite biomass or sequestered parasite biomass (Table 4 ). Among endothelial activation markers, the only comparison that reached close to significance was the association between transcript levels reported by the DBLa2/1.1/2/4/7 primers and sVCAM-1 levels in severe malaria ( P = 0.054, when adjusted for multiple comparisons, Table 4 ).
close to significancep = 0.0541.1× alpha
The difference between Pediatrics and PCCM was close to significance but did not quite reach it (adjusted p = 0.054) (For details, see Table 3 ; Figure 5 ). 4 Discussion Antimicrobial resistance in bacteria not only increases the risk of nosocomial infections but also prolongs hospital stays, escalates drug consumption, and further amplifies the economic burden on patients ( 12 ).