In the force discounting task, in the [0; 600 ms] epoch after action onset, corresponding to the time during which the force was exerted ( S1 Fig ), 50/92 neurons showed a significant change in rate compared to pre-go signal rate (10 decreased and 40 increased; Fig 3B ), and the activation was clearly significant at the population level (t(91) = 15.29; p < 10 −26 ; Fig 3E ).
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The dispersion parameter is clearly significant ( φ ˆ = 9.26 ; p<2e-16), indicating that there is strong evidence of overdispersion in the data that needs to be captured.
This raises the question whether the observed alteration in mib1 ta52b mutant neural tube proportions may be a secondary consequence of this reduction in cell number? Our observations argue against this hypothesis: First, the injection of NICD promotes a partial but clearly significant (p = 1.14E-08) restoration of neural tube proportions (Fig. 8p,q ) while triggering only a minor and non-significant (p = 0.129) increase in neural tube cell number (Supplementary Fig.
The computed probability p(uncorrel) reveals that the correlation is clearly significant because the probability that r is equal to zero is far below 0.05 ( p = 5.31 × 10 −07 ).
This correlation was larger than the prespecified threshold of ρ = 0.30 and clearly significant with p < 2×10 -6 (Table 2 and Table 3 ).
This remarkable result is clearly significant (Fisher's exact test, P < 0.00001).
This difference is clearly significant (two-tailed Fisher exact test, p < 0.00001).
Beginning with occurrence as source language and LPI rank, we note that the correlation is positive, not exceptionally strong, but clearly significant ( R = 0.41, p = 3.9e-05).
These analyses demonstrated for example a clearly significant enrichment for ESRRA binding motifs (∼2-fold, P = 4.8E-5) ( Supplementary Data Sheet 1 ), suggesting that the transactivation activity of ESRRA may depend on the DNA methylation status of its binding motif.
Also, all the other measures showed clearly significant results resembling the associations with the ACarPA status (all p < 5.7 × 10 –5 , Supplementary Table S3 ).
The LRT statistic for dispersion is 85.87 and is clearly significant with one degree of freedom and p-value < 0.0001 (refer to Eq (10) ).
Heterogeneity was clearly significant for the pooled result of HbA1c ( df = 8, p < 0.0001, I 2 = 82%).
In addition to our crucial comparison of the two interference effects, the modulation of the load over the benefits observed for the valid condition was clearly significant, χ 2 (1) = 374.11, p < 0.0001; in fact, we observed (see Figure 7 ) a much larger modulation for the benefits (64 ms larger for high compared to low perceptual load), than for the costs (11 ms larger for high perceptual load).
Our results are consistent with those reported elsewhere, indicating reduced low back pain (VAS score) in 75% and reduced disease activity, which is clearly significant during the first 2–3 months and is maintained at ∼6 months according to the VAS score (−3.25, P < 0.0001), BASDAI (−1.86, P < 0.0001) and ASDAS (−1.0, P < 0.0001).
Overall, the full-null model comparison was clearly significant, χ 8 2 = 60.932 , p < 0.0001.
Regarding the total cholesterol levels, a clearly significant difference was observed between ApoE-KO and WT mice, independently of the diet, at every evaluated time point ( Figure 1B , p < 0.0001).
Regardless of such variability in RA patients, there was a clearly significant difference between both groups (RA mean 1.2 ± 3.18% [0–19.50%] vs. healthy control mean 0.07 ± 0.1% [0–0.59%], p < 0.0001, Fig. 3 b upper panel).
In Figure 2 as well as in Figure 3 of their study ( 1 ) they demonstrated a clearly significant difference between the TYM scores between controls and AD patients as well as between moderate AD and severe AD patients (both p < 0.0001).
For the asymmetric component of shape variation in the falls, differentiation among compass orientations was clearer, with less overlap of confidence ellipses for the CV scores (Figure 3d ) and clearly significant results in the permutation test (Goodall's F = 4.73, p < .0001; Pillai's trace = 0.152, p < .0001).
A difference from global connectivity is that in this case the difference between healthy and control subjects is clearly significant (p-value < 0.0001).
The only positive results were observed in a subgroup with a high rate of spontaneous mutation in CTCs, with a clearly significant RR (83 vs. 33%; p = 0.0002) [ 56 , 70 ]; Olaparib–Abiraterone.
A clearly significant difference between the two groups could be noted (F(1, 204) = 14.2; p = 0.0002).
Exploratory subgroup analysis showed that the prognostic impact of MPSol probability was clearly significant in the patients with neoadjuvant CCRT treatment ( n = 218, p = 0.00085), but it was not significant in those with definitive CCRT treatment ( n = 198, p = 0.51) ( Figure S5 ).
For model 3 predicting the behavioral factor II as a response, which was mainly comprised of the proportion of time tail wagging, licking the trainer’s hand or face, and the frequency of lips licking, we found a clearly significant full-null model comparison (c2 = 27.44, df = 6, p < 0.001).
The results of the multiple regression hierarchy showed that the joint impact of gender and age with regards to being healthy or unhealthy only explained 2.7% of the total variance (adjusted R2), although the equation is clearly significant (F 2,320 = 96.3, p < 0.001).