PGA decreased from 1.2 [1–2.7] at adalimumab initiation to 0.5 [0.1–1.4] ( p = 0.017; borderline significant) at 12 months.
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p=0.09
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There was also a borderline significant excess of endometrial cancer in the same age group, but no raised risk of ovarian cancer ( P =0.018 compared with the risk in the younger-onset diabetes patients).
Only race had an association with RFS that was borderline significant (adjusted p-value = 0.018) after correcting for multiple testing, suggesting the lack of prognostic prediction power of these conventionally used variables.
After full adjustment, the TyG index lost significance (continuous variable: OR = 1.24, P = 0.149; only Q3 group was borderline significant OR = 2.18, P = 0.018), and the ZJU index showed no statistical significance in all fully adjusted models (continuous variable: P = 0.291; highest group OR = 1.70, P = 0.112).
We tested for interaction between SES and ethnicity in relation to pattern scores and found a borderline significant interaction for the full-fat ( p = 0.018) and meat pattern ( p = 0.017), whereas no interaction was present for the snacking ( p = 0.324) and healthy ( p = 0.260) pattern.
3.1 AD and cortical thickness We found a borderline significant association between AD and the decreased CT in the posterior cingulate (IVW‐MR: β = −0.065, p = 0.018, p‐corrected = 0.551) and isthmus cingulate regions (IVW‐MR: β = −0.086, p = 0.003, p‐corrected = 0.188) (Figure 2 , Table S3 ). 3.2 AD and CA We found a borderline significant association between AD and the decreased SA in the supramarginal region (IVW‐MR: β = −0.047, p = 0.044, p ‐corrected = 0.714) and the increased SA in the isthmus cingulate regions (IVW‐MR: β = 0.053, p = 0.018, p ‐corrected = 0.714) (Figure 2 , Table S3 ).
A formal test showed that a model without sex differences did not worsen the fit of the model significantly, based on a p-value threshold of 0.01 but this test was borderline significant (p = 0.0195).
A borderline significant increase in serum β -carotene levels was found at D3 compared to PO ( P = 0.02) within the eEVAR group.
VAT had a borderline significant association with non-HDL cholesterol; P = 0.02, r 2 = 0.15, 0.03 (0.02–0.04) mmol/l increase for each 10 cm 3 increase in VAT.
Minimum arm pain and arm pain frequency were borderline significant between the NSE and PPA groups (p = 0.02).
Among females, the results for red meat were borderline significant and mediation was observed for BMI (mediation effect 2.29%, p = 0.02, q = 0.10) and WC (2.92%, p = 0.02, q = 0.10), but not for body fat % (mediation effect 2.43% p = 0.04, q = 0.20).
Univariate analysis of overall survival using the Cox model showed that stage ( P < .001), CA19-9 levels ( P = .004), and CRHR1 status ( P = .038) were significant factors, and the subsequent multivariate analysis revealed that of these, stage and postoperative CA19-9 levels were borderline significant factors ( P = .02 and .001, respectively) without multicollinearity ( Table 3 ).
1D ) were still borderline significant ( P = .02 and .05, respectively).
There was a borderline significant increase in square root‐transformed corrected height percentile over time (0.11 ± 0.046 (SD) [95% CIs 0.018, 0.20]; p = 0.020).
In the CU+ subgroup, there was a significant negative correlation between the global clustering coefficient and tau PET load in early metaVOI, which became borderline significant when we corrected for age and sex as covariates ( ρ = −0.62, P = 0.02, p adj = 0.05) ( Fig. 2 ).
For the study population, both young adults (ages 19–54 years; n = 100; TT = 61, G -allele carriers = 39) and older adults (ages 55+ years; n = 124, TT = 69, G -allele carrier = 55), carriage of the G -allele was associated with a borderline significant retention of FOXO3 expression as a function of age (Fig. 3a , younger participants: P = 0.02; Fig. 3b : P = 0.08).
Further, we observed a borderline significant association between ghrelin levels and post-vaccination antibody levels in overweight children (regression coefficient 0.009, p = 0.02) ( Table 3 ).
The LPL S447X variant showed borderline significant association with weight ( p = 0.02) with 447X homozygotes weighing almost 5 kg less than S447 homozygotes.
Although the difference in index between medium and high TCP samples was borderline significant (P = 0.02), the majority of medium TCP samples (78%) were classified as high TCP by the molecular profile.
There were significant differences in AST between the Half-FLU and FLU groups ( P = .0086), and between the FLU and Arg groups ( P < .0001), and borderline significant differences between the Half-FLU and Arg groups ( P = .02).
As shown in Table 1 , the total number of live piglets tended to be slightly higher in the control group compared to albumin-supplemented groups, although the difference was only borderline significant (KW p = 0.02; DSCF p ≥ 0.08).
Carriers of the rs356168-G allele demonstrated a borderline significant decrease of SNCA -mRNA levels in temporal brain tissues ( p = 0.02) compared to individuals homozygous for the ‘A’ allele.
A univariate analysis revealed that FKBPL was also a significant predictor of relapse free interval (RFI) within the ER positive patient group, but it was only borderline significant within the smaller tamoxifen treated patient group (HR = 1.32 95% CI 1.05–1.65, p = 0.02 and HR = 1.23 95% CI 0.99–1.54, p = 0.06, respectively).
Alcohol use and stressful life events (ie, relationship breakup) were also borderline significant ( P <0.02) with increased insomnia risk among male nonusers, but no association among female nonusers.
Subgroup analysis showed a borderline significant association between haplotype GCG and MMP9 levels (uncorrected p = 0.020 and corrected false discovery rate p = 0.073), but with no evidence of interaction.