Association of PIK3CA mutation status and gene signatures with Ki67 There was a borderline significant difference ( P = 0.051) in baseline Ki67 between PIK3CA WT and mutation samples, with patients with the mutation having lower levels of proliferation (Table 2 ).
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The difference-in-differences estimator result showed a 9% difference in clean cord care practices among the participants (p = 0.025), 12.2% in skin to skin care (p = 0.022), and borderline significant increase in early initiation of breastfeeding (10.5%, p = 0.051).
The relationship between comorbidity and self-care maintenance was borderline significant, indicating that with every unit increase in comorbidity score there was an increase in self-care maintenance score by 1 unit ( p = 0.051). 3.3.2.
When accuracy differences across the 4 subtypes (radiograph, clinical photo, schematic illustration, and mixed) were assessed using chi-square tests, subtype-level variability within each model was significant (Claude-4 Opus, P = .040; Gemini 2.5 Pro, P = .005) or borderline significant (ChatGPT-4o, P = .051), confirming that image subtype substantially influenced model performance.
In the present study, higher expression was detected in patients with MRD 0.1 to < 10% on day 15, and the difference in expression was significant for CD8+ ( P = 0.042) and borderline significant for CD4 + T lymphocytes ( P = 0.051).
Level of education was borderline significant (p = 0.051); with the tertiary educated more likely to recall the campaign, (AdjOR 1.36, 95%CI 0.99–1.86).
In this model, the association between shame and depression was borderline significant ( p = 0.051).
The differences in NCL expression were statistically significant between neuroblastoma and pre-B ALL ( p = 0.003), between neuroblastoma and the controls ( p < 0.001), and borderline significant between pre-B ALL and the controls ( p = 0.051).
The indirect effect of HbA1c on CAD severity through MPV was borderline significant (Sobel z = 1.95, p = 0.051; indirect standardised effect = 0.024, 95% CI: -0.001 to 0.051).
BMI showed a borderline significant effect ( p = 0.051), while sex ( p = 0.411) and height ( p = 0.816) did not significantly influence COP metrics.
No statistically significant difference was observed in VD parameters of the SCP and DCP ( P = 0.102–0.894); only a borderline significant decrease was found in the temporal SCP VD ( P = 0.051) in the post-COVID group.
There was a borderline significant difference in CN fiber width ( p = 0.051) and RNFL nasal inferior thickness ( p = 0.056).
Also, a borderline significant difference showed less patients with MACS-positive profile in group UT versus BT (24.45% versus 36.59%, p = 0.051).
Furthermore, the probability of reporting higher loneliness in January 2021 (T4) than in April 2020 (T0) was borderline significant ( p = .051).
Fluid gel with or without hrDecorin, significantly lowered levels of fibronectin IR to 31.6 ± 5.8% and 13.9 ± 5.3%, respectively, demonstrating borderline significant differences ( p = 0.051) between the two eye drop treatment groups.
When using 22C3 CPS ≥ 1 cut-off, NHG was significantly associated with PD-L1 IHC expression ( p = 0.045) and Ki-67 borderline significant ( p = 0.051; Additional file 3 : Table S3).
It was also surprising that there are borderline significant ( P = 0.051) differences reported between the groups for sexual function and sexual distress at 28 weeks, while their table 3 suggests otherwise when looking at sexual distress.
The difference in recurrence rate between patients with STUMP (6.3%) and the reclassified group (66.7%) was borderline significant (P = 0.051).
Huang et al only analyzed whethe RASSF1A promoter methylation was linked to tumor stage (five studies with 252 cases) and grade (four studies with 190 cases), showing that RASSF1A promoter methylation had a borderline significant correlation with tumor stage ( P =0.051) and a significant association with tumor grade ( P =0.001). 49 Our meta-analysis involving more patients suggested that RASSF1A promoter methylation was significantly linked to tumor grade (13 studies with 686 patients with RCC, P <0.001) and clinical stage (8 studies with 463 patients with RCC, P =0.001).
Central macular thickness was significantly lower in intravitreal dexamethasone implant–treated eyes than in topical carbonic anhydrase inhibitors–treated eyes at Months 1 and 7, whereas mean best-corrected visual acuity was better in eyes treated with topical carbonic anhydrase inhibitors at Month 12 (borderline significant P = 0.0510).
Multivariate Cox proportional hazard analysis showed a significant association of this SNP with myocardial infarction ( p = 0.013; Wald test) and a borderline significant association of rs2768759 and all-cause mortality ( p = 0.051; Wald test).
The third important finding of this study is that low eGFR was significantly associated with new-onset hypertension in the traditional definition population ( p < 0.001), whereas the association was only borderline significant in the new definition population ( p = 0.051).
However, when comparing individual sports, a borderline significant difference was observed (Q = 3.801, p = 0.051) between kickboxing (moderate increase in T levels, ES = 0.86) and taekwondo (small decrease in T levels, ES = - 0.58).
The difference in the frequency of responses between both groups was borderline significant (Chi 2 = 7.764, p = 0.051) with professionals from clinics indicating more often an increase in severity.
Conversely, in patients with collateral status grade 3, bridging therapy demonstrated no statistically significant association with functional independence (adjusted OR [95% CI]: 0.473 [0.121–1.842], P = 0.280), whereas the improvement in global functional outcomes showed borderline significant trend (adjusted common OR [95% CI]: 0.391 [0.150–0.991], P = 0.051) that did not reach the pre-specified statistical threshold (Table 4 and Fig. 2).